Rchr
J-GLOBAL ID：201801006982986946   Update date: Nov. 22, 2024

Kaji Kosuke

カジ コウスケ | Kaji Kosuke
Affiliation and department：
Nara Medical University

About Nara Medical University


Research field  (1)： Gastroenterology
Research keywords  (5)： hepatic encephalopathy ,  liver regeneration ,  cholangiocarcinoma ,  hepatocellular carcinoma ,  liver fibrosis
Research theme for competitive and other funds  (8)：
  • 2024 - 2026 Pathophysiological analysis and therapeutic development based on vWF-ADAMTS13 regulation for poor prognostic factors in liver cirrhosis
  • 2022 - 2025 血液凝固制御因子ADAMTS13による急性肝不全新規治療法とバイオマーカーの開発
  • 2021 - 2024 Novel Liver Cirrhosis Treatment by Drug Repositioning and Leaky Gut Control
  • 2021 - 2024 歯周病と慢性肝疾患病態の関連解明-新たな肝疾患進展予防施策の探索
  • 2021 - 2023 Development research of novel pathophysiology and therapy for hepatorenal syndrome in cirrhosis-Thrombotic microangiopathy and recombinant ADAMTS13 therapy-
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Papers (243)：
  • Fumimasa Tomooka, Koh Kitagawa, Akira Mitoro, Yukihisa Fujinaga, Norihisa Nishimura, Tadashi Namisaki, Takemi Akahane, Kosuke Kaji, Shohei Asada, Shinya Sato, et al. Unilateral drainage and chemotherapy prolong the patency of a plastic stent placed above the sphincter of Oddi in patients with malignant hilar biliary obstruction. DEN open. 2025. 5. 1. e404
  • Jun-Ichi Hanatani, Koh Kitagawa, Fumimasa Tomooka, Shohei Asada, Akira Mitoro, Yukihisa Fujinaga, Norihisa Nishimura, Shinya Sato, Akihiko Shibamoto, Yuki Fujimoto, et al. Impact of the COVID-19 pandemic on the treatment of acute cholangitis caused by choledocholithiasis: A single-center retrospective study in Japan. DEN open. 2025. 5. 1. e371
  • Aritoshi Koizumi, Kosuke Kaji, Norihisa Nishimura, Shohei Asada, Takuya Matsuda, Misako Tanaka, Nobuyuki Yorioka, Yuki Tsuji, Koh Kitagawa, Shinya Sato, et al. Effects of elafibranor on liver fibrosis and gut barrier function in a mouse model of alcohol-associated liver disease. World journal of gastroenterology. 2024. 30. 28. 3428-3446
  • Takahiro Kubo, Norihisa Nishimura, Kosuke Kaji, Fumimasa Tomooka, Akihiko Shibamoto, Satoshi Iwai, Junya Suzuki, Hideto Kawaratani, Tadashi Namisaki, Takemi Akahane, et al. Role of Epiregulin on Lipopolysaccharide-Induced Hepatocarcinogenesis as a Mediator via EGFR Signaling in the Cancer Microenvironment. International journal of molecular sciences. 2024. 25. 8
  • Shohei Asada, Kosuke Kaji, Norihisa Nishimura, Aritoshi Koizumi, Takuya Matsuda, Misako Tanaka, Nobuyuki Yorioka, Shinya Sato, Koh Kitagawa, Tadashi Namisaki, et al. Tofogliflozin Delays Portal Hypertension and Hepatic Fibrosis by Inhibiting Sinusoidal Capillarization in Cirrhotic Rats. Cells. 2024. 13. 6
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MISC (310)：
  • 浪崎正, 竹田惣一, 辻裕樹, 鍛治孝祐, 吉治仁志. 進行肝細胞癌に対する腸管透過性を指標としたアテゾリブマブ+ベバシズマブ併用療法の治療効果予測. 日本肝がん分子標的治療研究会プログラム・抄録集. 2024. 29th
  • 高谷広章, 高谷広章, 浪崎正, 村田晃児, 辻裕樹, 鍛治孝祐, 相澤茂幸, 森岡千惠, 野口隆一, 吉田太之, et al. ラジオ波焼灼療法におけるシステムによる治療効果と安全性の差違. 肝臓. 2023. 64. Supplement 1
  • 友岡文優, 鍛治孝祐, 北川洸, 西村典久, 久保貴裕, 芝本彰彦, 岩井聡始, 鈴木淳也, 辻裕樹, 藤永幸久, et al. Sulforaphane potentiates the cholangiocarcinoma inhibitory effect of gemcitabine via HDAC inhibition. 日本がん転移学会学術集会・総会プログラム抄録集. 2023. 32nd
  • 依岡伸幸, 浪崎正, 辻祐樹, 瓦谷英人, 鍛治孝祐, 吉治仁志. 難治性腹水濾過濃縮再静注法(CART)による血液凝固因子の回収. 日本門脈圧亢進症学会雑誌. 2023. 29. 3
  • 大矢裕一, 能崎優太, 能崎優太, 山咲茉名美, 永田拓也, 加藤匠真, 村瀬敦郎, 鍛治孝祐, 吉治仁志, 朝井章, et al. ヒアルロン酸被覆高分子ミセルを用いたドラッグデリバリーによる肝障害抑制. 日本DDS学会学術集会プログラム予稿集. 2023. 39th
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Books (11)：
  • 肝硬変治療マニュアル
    南江堂 2019
  • 内科学書 第9版
    中山書店 2019
  • The Evolving Landscape of Liver Cirrhosis Management
    シュプリンガー 2019
  • Alcoholic/Non-Alcoholic Digestive Diseases
    シュプリンガー 2019
  • 新・今日の処方
    南江堂 2019
ｍore...
Education (2)：
  • 2006 - 2010 Nara Medical University Medical Faculty
  • 1997 - 2003 Nara Medical University Medical Faculty Medical Department
Professional career (1)：
  • 医学博士 (奈良県立医科大学 消化器病態制御医学)
Work history (6)：
  • 2024/10 - 現在 奈良県立医科大学 消化器内科学講座 (消化器・代謝内科) 准教授
  • 2018/04 - 2024/09 Nara Medical University Third Department of Internal Medicine Lecturer
  • 2015/09 - 2018/03 Nara Medical University Third Department of Internal Medicine Assistant professor
  • 2012/11 - 2015/08 National Cancer Institute Laboratory of Experimental Carcinogenesis Research fellow
  • 2010/04 - 2012/10 Nara Medical University Third Department of Internal Medicine Postdoctoral fellow
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Awards (8)：
  • 2022/10 - 日本消化吸収学会 日本消化吸収学会 学会賞
  • 2019/06 - 日本肝がん分子標的治療研究会 第9回 沖田賞
  • 2018/05 - Cytoprotection研究会 第36回 奨励賞
  • 2016/11 - AASLD Presidential Poster of Distinction
  • 2015/11 - AASLD Presidential Poster of Distinction
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