INOUE DAISUKE

イノウエダイスケ | INOUE DAISUKE

Affiliation and department：
Job title： Assistant Professor

Research field (2)： Pharmaceuticals - health and biochemistry , Clinical pharmacy

Research keywords (4)： Formulations , Pharmacokinetics , Drug delivery system , Pharmaceutics

Research theme for competitive and other funds (7)：

2025 - 2028 脳内概日リズムに同調させた経鼻脳薬物送達法による神経炎症治療薬の開発
2025 - 2026 Gタンパク質共役型受容体を標的とするDNAアプタマー医薬の実用化
2022 - 2025 睡眠サイクルを考慮した経鼻脳薬物送達法の構築及び神経変性疾患治療戦略への応用
2019 - 2023 経鼻-脳実質内薬物送達法による中枢系疾患治療を指向した神経炎症抑制効果の検討
2017 - 2019 Mechanistic investigation of nose to brain drug delivery pathway and application of intranasal administration to drug therapy for CNS disorders

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Papers (31)：

Yoshihiro Seto, Shun Tokeshi, Daisuke Inoue, Fumiyasu Okazaki, Hideto To. Diurnal variations of neurokinin-1 receptor defines dosing time-dependent differences in antitumor effects of aprepitant in mice. Journal of Pharmacological Sciences. 2025. 158. 3. 193-198
Daisuke Inoue, Yoshihiro Seto, Hideto To. Nasal Residence Depending on the Administered Dosage Form: Impact of Formulation Type on the In Vivo Nasal Retention Time of Drugs in Rats. Pharmaceutics. 2025. 17. 7. 863
Yoshihiro Seto, Yuki Ohara, Manami Tachi, Mari Tomonari, Daisuke Inoue, Fumiyasu Okazaki, Yasuhiro Tsuji, Hideto To. Repeated Valproic Acid Administration Fundamentally Ameliorated Cisplatin-Induced Mechanical Allodynia in Rats. International Journal of Molecular Sciences. 2025. 26. 11. 4977
Daisuke Inoue, Ayari Yamashita, Hideto To. Development of In Vitro Evaluation System for Assessing Drug Dissolution Considering Physiological Environment in Nasal Cavity. Pharmaceutics. 2022. 14. 11. 2350
Daisuke Inoue, Ayari Yamashita, Hideto To. Formulation and In Vitro Characterization of a Vacuum-Dried Drug-Polymer Thin Film for Intranasal Application. Polymers. 2022. 14. 14. 2954

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MISC (2)：

Daisuke Inoue. Development of prediction system for drug absorption after intranasal administration incorporating physiologic functions of nose -Estimation of in vivo drug permeation through nasal mucosa using in vitro membrane permeability-. YAKUGAKU ZASSHI. 2021. 141. 11. 1235-1240
Daisuke Inoue. For Development of Nasal Formulations. Journal of Pharmaceutical Science and Technology, Japan. 2021. 81. 3. 231-235

Books (1)：

New Horizon of Middle-Molecule DDS Development
CMC Publishing CO.,LTD. 2022 ISBN:9784781316598

Lectures and oral presentations (3)：

鼻腔内生理機能を考慮した経鼻吸収予測システムの開発
(第71回日本薬学会関西支部大会 2021)
Nose-to-Brain Drug Delivery System for Nasal Formulation Development
(The 36th Annual Meeting of the Academy of Pharmaceutical Science and Technology, Japan (APSTJ) 2021)
動態学的評価に基づく鼻腔から脳脊髄液を介した脳実質への薬物送達機構の解析
(第36回日本DDS学会学術集会 2020)

Education (3)：

- 2013 Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Division of Pharmaceutical Sciences
- 2009 Okayama University Graduate School of Medicine , Dentistry and Pharmaceutical Sciences Pharmaceutical Sciences
- 2007 Shujitsu University School of Pharmacy

Professional career (1)：

Ph.D (Okayama University)

Work history (4)：

2022/02 - 現在 University of Toyama School of Pharmacy and Pharmaceutical Sciences Assistant Professor
2019/04 - 2022/01 Ritsumeikan University College of Pharmaceutical Sciences Assistant Professor
2013/10 - 2019/03 Shujitsu University School of Pharmacy Assistant professor
2009/04 - 2013/09 Shujitsu University School of Pharmacy Assistant professor

Committee career (13)：

2025/06 - 現在 Pharmaceutics (MDPI) Special Issue Editor: Advances and Challenges in Nasal Formulation Developments, 3rd Edition
2024/11 - 現在 Pharmaceutics (MDPI) Special Issue Editor: CNS Drug Delivery: Recent Advances and Challenges
2024/04 - 現在 International Journal of Molecular Sciences (MDPI) Special Issue Editor: Nose-to-Brain Drug Delivery: Opportunities and Challenges
2022/09 - 現在 MDPI Topical Advisory Panel Member of International Journal of Molecular Sciences
2022/04 - 現在日本薬剤学会英語セミナー委員

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Awards (9)：

2025/03 - 富山大学附属病院臨床研究開発推進センター 2024年度富山大学若手向け研究発表会研究奨励賞
2021/05 - 2021年度日本薬剤学会優秀論文賞
2021/05 - 2021年度日本薬剤学会旭化成創剤研究奨励賞
2021/01 - 2020年度日本薬学会関西支部奨励賞
2018/10 - 2018 International Meeting on 22nd MDO and 33rd JSSX Best Poster Award

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Association Membership(s) (6)：

American Association of Pharmaceutical Scientists , THE PHARMACEUTICAL SOCIETY OF JAPAN , THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS , THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM , THE ACADEMY OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, JAPAN , The Society of Polymer Science, Japan (SPSJ)

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