Research theme for competitive and other funds (5):
2014 - 2016 Structure-function studies of bacterial mitoNEET system
2012 - 2015 Systemic and long term analysys of O2- hyperproduction mice
2012 - 2014 Structure-function of bacterial mitoNEET homologs
2012 - 2012 Effects of Change in Purine Metabolism on Accumulation of Aggregated Proteins in the Cell
2008 - 2010 Phasogenesis study of XOR mutant knock-in mouse.
Papers (18):
Teruo Kusano, Tomoko Nishino, Ken Okamoto, Russ Hille, Takeshi Nishino. The mechanism and significance of the conversion of xanthine dehydrogenase to xanthine oxidase in mammalian secretory gland cells. Redox Biol. 2023. 59. 102573
Sonia Nasi, Mariela Castelblanco, Véronique Chobaz, Driss Ehirchiou, Alexander So, Ilaria Bernabei, Teruo Kusano, Takeshi Nishino, Ken Okamoto, Nathalie Busso. Xanthine Oxidoreductase Is Involved in Chondrocyte Mineralization and Expressed in Osteoarthritic Damaged Cartilage. Frontiers in cell and developmental biology. 2021. 9. 612440
Kusano T, Ehirchiou D, Matsumura T, Chobaz V, Nasi S, Castelblanco M, So A, Lavanchy C, Acha-Orbea H, Nishino T, et al. Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth. Nature communications. 2019. 10. 1. 4904
Shinsuke Kato, Masako Kato, Teruo Kusano, Takeshi Nishino. New Strategy That Delays Progression of Amyotrophic Lateral Sclerosis in G1H-G93A Transgenic Mice: Oral Administration of Xanthine Oxidoreductase Inhibitors That Are Not Substrates for the Purine Salvage Pathway. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. 2016. 75. 12. 1124-1144