Rchr
J-GLOBAL ID:201801007285677214   Update date: Jan. 31, 2024

Kusano Teruo

クサノ テルオ | Kusano Teruo
Affiliation and department:
Research field  (3): Pathobiochemistry ,  Molecular biology ,  Medical biochemistry
Research keywords  (9): タンパク質コンフォメーション変換 ,  金属タンパク質 ,  ヘムタンパク質 ,  ラクトペルオキシダーゼ ,  キサンチン酸化還元酵素 ,  Reactive oxygen species ,  metabolism ,  Molecular biology ,  Biochemistry
Research theme for competitive and other funds  (5):
  • 2014 - 2016 Structure-function studies of bacterial mitoNEET system
  • 2012 - 2015 Systemic and long term analysys of O2- hyperproduction mice
  • 2012 - 2014 Structure-function of bacterial mitoNEET homologs
  • 2012 - 2012 Effects of Change in Purine Metabolism on Accumulation of Aggregated Proteins in the Cell
  • 2008 - 2010 Phasogenesis study of XOR mutant knock-in mouse.
Papers (18):
  • Teruo Kusano, Tomoko Nishino, Ken Okamoto, Russ Hille, Takeshi Nishino. The mechanism and significance of the conversion of xanthine dehydrogenase to xanthine oxidase in mammalian secretory gland cells. Redox Biol. 2023. 59. 102573
  • Sonia Nasi, Mariela Castelblanco, Véronique Chobaz, Driss Ehirchiou, Alexander So, Ilaria Bernabei, Teruo Kusano, Takeshi Nishino, Ken Okamoto, Nathalie Busso. Xanthine Oxidoreductase Is Involved in Chondrocyte Mineralization and Expressed in Osteoarthritic Damaged Cartilage. Frontiers in cell and developmental biology. 2021. 9. 612440
  • Kusano T, Ehirchiou D, Matsumura T, Chobaz V, Nasi S, Castelblanco M, So A, Lavanchy C, Acha-Orbea H, Nishino T, et al. Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth. Nature communications. 2019. 10. 1. 4904
  • Shinsuke Kato, Masako Kato, Teruo Kusano, Takeshi Nishino. New Strategy That Delays Progression of Amyotrophic Lateral Sclerosis in G1H-G93A Transgenic Mice: Oral Administration of Xanthine Oxidoreductase Inhibitors That Are Not Substrates for the Purine Salvage Pathway. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. 2016. 75. 12. 1124-1144
  • Masahiro Yamaguchi, Ken Okamoto, Teruo Kusano, Yoko Matsuda, Go Suzuki, Akira Fuse, Hiroyuki Yokota. The Effects of Xanthine Oxidoreductase Inhibitors on Oxidative Stress Markers following Global Brain Ischemia Reperfusion Injury in C57BL/6 Mice. PLOS ONE. 2015. 10. 7. e0133980
more...
MISC (20):
Lectures and oral presentations  (65):
  • キサンチン酸化還元酵素の活性変換機構:臓器局在および生理作用
    (第95回日本生化学会大会 2022)
  • SDS-PAGE後にゲル内固定されたヒトアルカリホ スファターゼ触媒活性は回復するか?
    (第95回日本生化学会大会 2022)
  • 出血性ショックによる急性肺障害に対するキサンチンオキシダーゼ阻害薬の有効性
    (第50回日本救急医学会総会・学術集会 2022)
  • 出血性ショックによる急性肺障害に対するキサンチンオキシダーゼ阻害薬の効果
    (第36回日本Shock学会学術集会 2022)
  • 変性アルカリホスファターゼの牛乳による活性回復
    (第94回日本生化学会大会 2021)
more...
Work history (2):
  • 2006/04 - 現在 Nippon Medical School
  • 2001/04 - 2006/03 Nippon Medical School
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