Research theme for competitive and other funds (18)：
2022 - 2025 Machine-learning prediction of the protein plasticity regions related to denaturation and aggregation
2019 - 2022 Development of bio-degradative composite resin containing alpha-1,3-glucan and enzyme for its recycling
2016 - 2019 Understanding of the molecular mechanism of chitinolysis by Paenibacillus sp. str. FPU-7 and the bacterial cell surface display system.
2013 - 2016 Elucidation of the catalytic mechanism of bacterial cell-surface-expressed chitinase ChiW and chitin oligosaccharide production by using the high transglycosylation activity of ChiW.
2011 - 2013 Cold adaptation of thermostable enzymes by surface loops' mutagenesis
2010 - 2012 Anti-oxidative mechanism mediated by the yeast Mpr1 that acetylates proline catabolism intermediate and its application
2009 - 2010 Development of novel regulators for controlling glutathione biosynthesis
2008 - 2009 植物孔辺細胞に局在する電位依存性K^+チャネルの構造と機能
2007 - 2008 Structural studies on bifunctional glutathione synthetic enzyme inorder to develop a new drug for chemotherapy
2006 - 2008 Anti-oxidative mechanism mediated by the yeast acetyltransferase Mpr1 and its application for breeding of useful yeasts
2006 - 2007 植物孔辺細胞に局在する電位依存性K^+チャネルの構造と機能
2003 - 2005 Structural and functional analysis and its application of the yeast novel N-asetylransferase that detoxifies a proline analogue
2003 - 2004 Structural analysis on the ligand specificity of γ-glutamylcysteine synthetase
2001 - 2002 ファイトケラチン合成酵素の構造及び機能解析
2000 - 2002 Crystal structure and reaction mechanism of urate oxidase from Bacillus sp.
1999 - 2000 Time-resolved X-ray crystallographic studies of enzyme reaction
Gengo Kashiwazaki, Marina Sumida, Sho Oda, Ryo Watanabe, Ryota Naka, Akihiro Nishikawa, Ryo Omikawa, Noriko Tsuchida, Takashi Kitayama, Takao Hibi. A boron dipyrromethene-derivative fluorescent probes for β-cyclodextrin and maltooligotose hydrophobicity recognition. Carbohydrate Polymer Technologies and Applications. 2024
Takafumi Itoh, Tomoki Ogawa, Takao Hibi, Hisashi Kimoto. Characterization of the extracellular domain of sensor histidine kinase NagS from Paenibacillus sp. str. FPU-7: nagS interacts with oligosaccharide binding protein NagB1 in complexes with N, N′-diacetylchitobiose. Bioscience, Biotechnology, and Biochemistry. 2024. 88. 3. 294-304
Gengo Kashiwazaki, Ryo Watanabe, Akihiro Nishikawa, Koyori Kawamura, Takashi Kitayama, Takao Hibi. A selective hybrid fluorescent sensor for fructose detection based on a phenylboronic acid and BODIPY-based hydrophobicity probe. RSC advances. 2022. 12. 24. 15083-15090
Niphawan Panti, Vipavee Cherdvorapong, Takafumi Itoh, Takao Hibi, Wassana Suyotha, Shigekazu Yano, Mamoru Wakayama. Functional analysis of α-1,3-glucanase domain structure from Streptomyces thermodiastaticus HF3-3. The Journal of general and applied microbiology. 2021. 67. 3. 85-91
Takafumi Itoh, Misaki Yaguchi, Akari Nakaichi, Moe Yoda, Takao Hibi, Hisashi Kimoto. Structural characterization of two solute-binding proteins for N,N'-diacetylchitobiose/N,N',N''-triacetylchitotoriose of the gram-positive bacterium, Paenibacillus sp. str. FPU-7. Journal of structural biology: X. 2021. 5. 100049-100049
Colorimetric High-Throughput Microplate Assay of Xylose Isomerase and Its Application to Improve the Enzyme Activity.
NOVA SCIENCE PUBLISHERS, INC. 2019
1988 - 1993 Kyoto University Graduate School of Agriculture
Professional career (1)：
博士(農学) (京都大学)
Work history (6)：
2019/04 - 現在 Fukui Prefectural University Faculty of Biotechnology
2011/04 - 現在 Fukui Prefectural University Faculty of Biotechnology Professor
2007/04 - 2011/03 Fukui Prefectural University Faculty of Biotechnology
2005/04 - 2007/03 Fukui Prefectural University Faculty of Biotechnology
1996/04 - 2005/03 Fukui Prefectural University Faculty of Biotechnology
1993/04 - 1996/03 花王株式会社 食品科学研究所
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Association Membership(s) (5)：
THE VITAMIN SOCIETY OF JAPAN
, CHEM-BIO INFORMATICS SOCIETY
, THE JAPANESE BIOCHEMICAL SOCIETY
, THE CRYSTALLOGRAPHIC SOCIETY OF JAPAN
, JAPAN SOCIETY FOR BIOSCIENCE
