Rchr
J-GLOBAL ID:201801007315622193
Update date: Mar. 06, 2024
Yamazaki Manabu
ヤマザキ マナブ | Yamazaki Manabu
Affiliation and department:
Research field (1):
Oral medicine (pathology)
Research keywords (4):
lipid metabolism
, apoptosis
, cell death
, oral cancer
Research theme for competitive and other funds (27):
- 2022 - 2025 腫瘍関連免疫抑制性細胞を標的とした口腔癌に対する新たな免疫療法の開発研究
- 2021 - 2024 細胞外基質環境下における腫瘍特異的なCD73誘導低酸素応答性増殖機構の解明
- 2021 - 2024 免疫学的アプローチによるびまん性浸潤口腔扁平上皮癌の制御に関する基礎的研究
- 2021 - 2024 死細胞貪食による口腔がん細胞活性化:脂質クオリティが果たす役割を探る
- 2021 - 2024 口腔扁平上皮癌の間質浸潤と側方上皮内進展:その相反的制御と分子基盤
- 2020 - 2023 自発性異常味覚の苦味の正体にせまる
- 2019 - 2022 Novel strategy for oral cancer targeting myeloid-derived suppressor cells
- 2019 - 2022 Basic research on multi-step tongue carcinogenesis model for realizing clinical sequence
- 2018 - 2021 Hypoxia-responsive CD73 promotes the growth and migration of pleomorphic adenoma cells
- 2018 - 2021 Novel strategy targeting myeloid cells-mediated invasion of oral cancer
- 2018 - 2021 Cell death-driven mechanisms for cancer progression: targeting the dying codes
- 2018 - 2021 Oral squamous cell carcinoma and cetuximab loop theory
- 2017 - 2020 Examination of five factors related to the diagnosis of phantogeusia.
- 2017 - 2019 Identification of novel targets and concepts for cancer therapy
- 2016 - 2019 Targeting strategy against myeloid suppressor cells in mouse model of aged oral cancer
- 2014 - 2019 Pathogenesis of chewing-related oral cancer in Myanmar: a molecular pathoepidemiological study
- 2015 - 2018 Hypoxia-responsive MYC promotes the survival and growth of pleomorphic adenoma cells in hypoxic conditions.
- 2015 - 2018 Phagocytosis of apoptotic cells by oral squamous cell carcinoma cells: a possible driving force for cancer progression
- 2015 - 2017 Molecular pathways and functional varieties of hemophagocytosis-induced keratinization in oral squamous cell carcinoma cells: from cell death to proliferation and invasion
- 2013 - 2017 Molecular patho-epidemiological study on the etiological background for oral superficial carcinoma among Asian ethnic groups
- 2013 - 2016 Proteome analysis of invasion starter molecules in oral squamous cell carcinoma
- 2013 - 2015 Upregulation of cancer cell functions by apoptotic cell engulfment
- 2012 - 2015 Survival of salivary pleomorphic adenoma cells under the hypoxia-responsive extracellular matrix biosynthesis
- 2011 - 2015 A molecular pathoepidemiological study on tobacco chewing-related oral cancer in Asian and African areas
- 2011 - 2012 Apoptotic cell engulfment by cancer cells
- 2010 - 2012 Molecular mechanisms of ghost cell formation and calcification in calcifying cystic odontogenic tumor (CCOT) cell lines
- 2007 - 2010 Pathogenesis of oral cancer due to chewing habits spread in Asia to East Africa
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Papers (88):
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Masaki Takamura, Yutaka Nikkuni, Takafumi Hayashi, Kouji Katsura, Hideyoshi Nishiyama, Manabu Yamazaki, Satoshi Maruyama, Jun-ichi Tanuma. Comparing the Diagnostic Accuracy of Ultrasonography, CT, MRI, and PET/CT in Cervical Lymph Node Metastasis of Oral Squamous Cell Carcinoma. Biomedicines. 2023. 11. 12. 3119-3119
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Satoshi Maruyama, Manabu Yamazaki, Tatsuya Abé, Jun Cheng, Takashi Saku, Jun-ichi Tanuma. Hypoxia-Induced Biosynthesis of the Extracellular Matrix Molecules, Perlecan and Fibronectin, Promotes the Growth of Pleomorphic Adenoma Cells In Vitro Models. Biomedicines. 2023. 11. 11. 2981-2981
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Toshiyuki Akimori, Manabu Yamazaki, Tatsuya Abé, Satoshi Maruyama, Kei Tomihara, Takeyasu Maeda, Jun-ichi Tanuma. Searching for new early detection markers of oral epithelial dysplasia and oral squamous cell carcinoma using oral liquid-based cytology. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 2023
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羽賀 健太, 山崎 学, 丸山 智, 阿部 達也, 小林 正治, 田沼 順一. 光干渉断層撮影を用いた3次元口腔癌モデルにおける癌浸潤の定量解析(Quantitative analysis of cancer cell invasion on 3D in vitro oral cancer models using optical coherence tomography). 日本癌学会総会記事. 2023. 82回. 970-970
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Nyein Nyein Chan, Manabu Yamazaki, Satoshi Maruyama, Tatsuya Abé, Kenta Haga, Masami Kawaharada, Kenji Izumi, Tadaharu Kobayashi, Jun-ichi Tanuma. Cholesterol Is a Regulator of CAV1 Localization and Cell Migration in Oral Squamous Cell Carcinoma. International Journal of Molecular Sciences. 2023. 24. 7. 6035
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MISC (78):
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泉健次, 内藤絵里子, 内藤絵里子, 井川和代, 羽賀健太, 小林亮太, 小林亮太, 齋藤夕子, 山崎学, 田沼順一, et al. 口腔癌と口腔粘膜に対する重粒子線照射の影響に関する3次元in vitroモデルを用いた研究. 日本口腔科学会学術集会プログラム・抄録集. 2023. 77th
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AMRIMOEZZ Yonesi, 冨原圭, 高塚団貴, 立浪秀剛, 山崎学, 高市真由, AMIRREZA Younesi, 山田慎一, 田沼順一, 野口誠. Rapamycin induces phenotypic alterations of oral cancer cells that facilitate antitumor T cell response. 日本口腔科学会学術集会プログラム・抄録集. 2023. 77th
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羽賀健太, 船山昭典, 長谷部大地, 佐久間英伸, 齋藤大輔, 新美奏恵, 曽束洋平, 山崎学, 田沼順一, 林孝文, et al. Extensive ameloblastic fibroma of the mandible in a middle-aged female. 日本口腔腫瘍学会総会・学術大会プログラム・抄録集. 2023. 41st
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内藤 絵里子, 高田 翔, 羽賀 健太, Suebsamarn Orakarn, Witsanu Yortchan, 小林 亮太, 鈴木 絢子, 山崎 学, 田沼 順一, 冨原 圭, et al. 口腔癌および口腔粘膜3次元in vitroモデルに対する重粒子線照射の影響に関する研究 異種放射線治療評価の標準化システムの構築. 新潟歯学会雑誌. 2022. 52. 2. 97-98
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内藤 絵里子, 小林 亮太, 羽賀 健太, 齊藤 夕子, 山崎 学, 田沼 順一, 井川 和代, 冨原 圭, 泉 健次. 正常口腔粘膜細胞と口腔癌細胞を用いた3次元in vitroモデル作製法とその応用. 日本口腔科学会雑誌. 2022. 71. 2. 61-61
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Education (2):
- 2002 - 2006 新潟大学大学院医歯学総合研究科 口腔病理学分野 大学院博士課程
- 1995 - 2001 Niigata University
Work history (5):
- 2023/04 - 現在 Niigata University Graduate School of Medical and Dental Sciences Associate Professor
- 2021/04 - 現在 新潟大学大学院 医歯学総合研究科 口腔病理学分野 講師
- 2009/07 - 現在 Niigata University Graduate School of Medical and Dental Sciences
- 2009/04 - 2009/06 Niigata University Graduate School of Medical and Dental Sciences
- 2006/04 - 2009/03 国立がん研究センター東病院 がん研究振興財団リサーチ・レジデント
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