Rchr
J-GLOBAL ID：201801007427363018   Update date: Nov. 25, 2024

Nishiyama Shuhei

ニシヤマ シュウヘイ | Nishiyama Shuhei
Affiliation and department：
Massachusetts General Hospital/Harvard Medical School Department of Neurology

About Massachusetts General Hospital/Harvard Medical School Department of Neurology


Job title： Research fellow
Research field  (1)： Neurology
Research keywords  (4)： Astrocyte ,  Multiple Sclerosis ,  Neuromyelitis Optica ,  Neurology
Research theme for competitive and other funds  (3)：
  • 2016 - 2019 Establishment of diagnosis and prognostic factors in cerebrospinal fluid based on the condition of inflammatory central nervous disease
  • 2014 - 2016 Molecular mechanism of astrocytic damage via endocytosis of AQP4 in Neuromyelitis optica
  • 2012 - 2014 The effect of NMO-IgG and complement against primary human astrocytes in culture.
Papers (99)：
  • Naoya Yamazaki, Tatsuro Misu, Yuki Matsumoto, Yoshiki Takai, Chihiro Namatame, Hirohiko Ono, Kimihiko Kaneko, Shuhei Nishiyama, Hiroshi Kuroda, Toshiyuki Takahashi, et al. The real-world impact of biologics for NMOSD: A retrospective single-center study compared with natural course and conventional treatments in Japanese. Multiple Sclerosis and Related Disorders. 2024. 92. 106176-106176
  • Shuhei Nishiyama, Jin Myong Seok, Amy E Wright, Itay Lotan, Takahisa Mikami, Natalia C Drosu, Natasha Bobrowski-Khoury, Monique R Anderson, Philippe A Bilodeau, Patrick Schindler, et al. Anti-aquaporin-4 immune complex stimulates complement-dependent Th17 cytokine release in neuromyelitis optica spectrum disorders. Scientific reports. 2024. 14. 1. 3146-3146
  • Tatsuro Misu, Yuki Matsumoto, Kimihiko Kaneko, Toshiyuki Takahashi, Yoshiki Takai, Hirohiko Ono, Chihiro Namatame, Shuhei Nishiyama, Juichi Fujimori, Hiroshi Kuroda, et al. Myelin oligodendrocyte glycoprotein antibody-associated disorders: An overview. Clinical and Experimental Neuroimmunology. 2023
  • Itay Lotan, Shuhei Nishiyama, Amy Wright, Jin Myoung Seok, Michael Levy. Electrophysiological and Histological Correlations of Optic Neuritis in the Dark Agouti Rat Model of Experimental Autoimmune Encephalomyelitis. Neuroscience. 2023. 524. 89-93
  • Pranay Srivastava, Shuhei Nishiyama, Sonia H Lin, Akriti Srivastava, Chienwen Su, Weiyi Peng, Michael Levy, Michael Schwarzschild, Yuehang Xu, Xiqun Chen. Peripheral MC1R activation modulates immune responses and is neuroprotective in a mouse model of Parkinson's disease. Research square. 2023
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MISC (123)：
  • 藤原一男, 松本勇貴, 三須建郎, 麦倉俊司, 高井良樹, 西山修平, 黒田宙, 高橋利幸, 藤盛寿一, 中島一郎, et al. 神経免疫疾患のエビデンスに基づく診断基準・重症度分類・ガイドラインの妥当性と患者QOLの検証 抗MOG抗体関連疾患と抗AQP4陽性視神経脊髄炎の頭部MRI画像における病変分布の比較検討. 神経免疫疾患のエビデンスに基づく診断基準・重症度分類・ガイドラインの妥当性と患者QOLの検証 令和2年度 総括・分担研究報告書(Web). 2021
  • Hiroshi Kuroda, Yoshiki Takai, Shuhei Nishiyama, Toshiyuki Takahashi, Tatsuro Misu, Ichiro Nakashima, Kazuo Fujihara, Masashi Aoki. Endothelial damage in patients with neuromyelitis optica spectrum disorder with aquaporin-4 IgG. MULTIPLE SCLEROSIS JOURNAL. 2020. 26. 9. NP77-NP78
  • Shuhei Nishiyama, Tatsuro Misu, Yoshiki Takai, Toshiyuki Takahashi, Ichiro Nakashima, Kazuo Fujihara, Masashi Aoki. Elevated cerebrospinal fluid-CRMP5 levels in acute phase of NMOSD with AQP4-IgG and the prognostic implication. MULTIPLE SCLEROSIS JOURNAL. 2020. 26. 9. NP77-NP77
  • 川嶋有朋, 福與なおみ, 竹澤佑介, 阿部裕, 植松貢, 植松有里佳, 高橋利幸, 西山修平, 黒田宙, 中島一郎, et al. 経過中抗AQP4抗体が再陽転化しその後再発したNMOSDの14歳女児例. 日本小児科学会雑誌. 2020. 124. 2
  • 川嶋 有朋, 福與 なおみ, 竹澤 佑介, 阿部 裕, 植松 貢, 植松 有里佳, 高橋 利幸, 西山 修平, 黒田 宙, 中島 一郎, et al. 一旦陰転化した抗体が陽転化した抗アクアポリン4抗体陽性患者. 脳と発達. 2020. 52. 1. 54-54
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Lectures and oral presentations  (13)：
  • 再発寛解型多発性硬化症に対してNatalizumabを使用した11例の検討
    (日本神経治療学会 2018)
  • CSF biomarker for NMOSD
    (PACTRIMS 2018 2018)
  • 抗MOG抗体関連疾患における血漿交換の有効性
    (東北免疫性神経疾患治療研究会 2018)
  • 再発寛解型多発性硬化症に対してNatalizumabを使用した11例の検討
    (日本神経免疫学会 2018)
  • Early pathological features in Fingolimod-associated PML with mild IRIS.
    (2018)
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Professional career (1)：
  • 医学博士 (東北大学)
Work history (3)：
  • 2020/07 - 現在 Massachusetts General Hospital/Harvard Medical School Department of Neurology Research fellow
  • 2014/04 - 2020/07 Tohoku University Hospital Neurology Assistant Professor
  • 2012/04 - 2014/03 Tohoku University Hospital Neurology Medical staff
Awards (5)：
  • 2018 - すばるの会(東北大学医学部神経内科同窓会) すばるの会論文賞
  • 2014 - European Charcot Foundation Young Investigators Awards for Multiple Sclerosis
  • 2013 - PACTRIMS MSJ-PACTRIMS Poster Award
  • 2011 - PACTRIMS Young Investigator Award
  • 2010 - Young Neuroimmunologist Award
Association Membership(s) (6)：
JAPANESE SOCIETY OF NEUROLOGICAL THERAPEUTICS ,  JAPANESE SOCIETY FOR APHERESIS ,  THE JAPANESE SOCIETY OF NEUROPATHOLOGY ,  THE JAPANESE SOCIETY OF NEUROIMMUNOLOGY ,  JAPANESE SOCIETY OF NEUROLOGY ,  THE JAPANESE SOCIETY OF INTERNAL MEDICINE
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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