Nakayama Koichi

Affiliation and department：
Job title： Professor

Research field (1)： Biomedical engineering

Research theme for competitive and other funds (43)：

2024 - 2029 腸オルガノイド細胞による立体構造体を用いた炎症性腸疾患に対する新たな治療法の確立
2024 - 2027 細胞のみで作製した3次元骨組織体を用いて広範囲骨欠損再建法の確立を目指す研究
2023 - 2027 Development of nextgeneration cellular artificial blood vessels for coronary artery bypass surgery using bio-3D printer
2023 - 2026 脂肪幹細胞での肛門機能低下の新規予防法開発と人工肛門括約筋による肛門機能再生研究
2023 - 2026 Development of cellular valve prosthesis using bio 3D printer technology

2022 - 2025 Basic research on the production of basic artificial organ skeletons and on the mass production and quality improvement

2022 - 2025 バイオ3Dプリンタを用いて広範囲骨欠損再建法の確立を目指す研究

2022 - 2025 iPS細胞由来中胚葉系細胞を用いて新たな靭帯再建法の確立を目指す研究

2021 - 2024 カーボンナノチューブを用いた自己細胞からなる人工管腔臓器の新たな作製技術の確立

2021 - 2024 補助人工心臓となりうる外科的に移植可能な三次元心筋細胞構造体の開発

2020 - 2024 Development of artificial blood vessel for lower limbs distal bypass using bio-3D printing technology and stem cell technology

2020 - 2023 短腸症候群に対する自己細胞のみからなる人工小腸による再生医療

2020 - 2023 Bio-fabrication of cerebral amyloid angiopathy model using Bio-3D printer and analysis of the pathophysiological mechanisms.

2020 - 2023 バイオ3Dプリンティング技術を応用した歯周組織再生型インプラントの開発

2020 - 2023 ブタ体内でヒト心筋組織を作製する手法の開発とその応用

2020 - 2023 スキャフォールドフリーの3次元構造体による機能を有する人工尿管の作成

2018 - 2023 Scaffold-free artificial trachea for tracheal deiseases

2018 - 2021 Drug response of scaffold-free cardiac constructs fabricated using bio-3D printing

2017 - 2021 Development of artificial blood vessel for coronary artery bypass using bio-3D printing technology and stem cell technology

2016 - 2021 Development of cardiovascular tissue using bio 3D printer, stem cell technology, and elucidation of cellular dynamics in tissue

2017 - 2020 Addition of human iPS-derived neural progenitors and endothelial cells influences the contractile function of cardiac spheroids.

2017 - 2020 Regenerative medicine for esophagus using a scaffold-free structure created with bio-three-dimensional printing technology

2017 - 2020 Bio-fabrication of cerebral amyloid angiopathy model using Bio-3D printer and analysis of the pathophysiological mechanisms.

2017 - 2020 Treatment of lymphedema with super microsurgery and bio-3D printing technique

2018 - 2019 バイオ3Dプリンタによる自己細胞凝集成熟能の機序解明と自己細胞由来心臓弁の開発

2017 - 2019 Novel method to visualize invasion and metastasis of pancreatic cancer using in vitro microenvironment model constructed by 3D bioprinter

2016 - 2019 バイオ3Dプリンタを用いた間葉系幹細胞構造体による腱・靱帯組織の再生技術の開発

2016 - 2018 Improvement of culture enviroment for scaffold-free cardiac construct

2015 - 2018 Development of the methods to fabricate a macro-scale liver tissue containinf the bile duct usgin 3D bioprinter

2015 - 2018 Osteochondral regeneration using allogenic implantation of somatic stem cell

2014 - 2017 Scaffold-free trachea and lung tissue engineering using bio-3D printing system

2014 - 2017 Development of vascular regenerative therapy using new tissue engineering

2013 - 2016 Development of new therapies for intractable diseases in pediatric surgery using stem cells from human exfoliated deciduous teeth

2013 - 2016 Development of regenerative therapy for cardiovascular organ from induced pluripotent stem cells using new tissue engineering

2012 - 2015 Development of new therapy for congenital metabolic disorders using functional three-dimensional liver structures constructed by stem cells from human exfoliated deciduous teeth

2011 - 2014 Osteochondral regeneration with scaffold free 3D-structure of swine adipose tissue-derived mesenchymal stem cells.

2011 - 2013 The evaluation of scaffold-free 3-D cardiac graft effect on heart failure model

2011 - 2013 Next generation prosthetic vascular graft with small diameters developed using new tissue engineering technology

2011 - 2012 Liver regeneration using stem cells from hteeth (SHED) for congenital metabol

2010 - 2012 Development of scaffold-free heart valve using autologous cell

2010 - 2012 Cardiac Regeneration using 3-Dimensional Cardiac Tissue

2010 - 2011 Cruciate injury model and cruciate regeneration with MSC by using of BPR system in micro-mini pig.

2007 - 2009 Development of cell based artificial joint

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Papers (112)：

Masahide Taguchi, Shohei Yoshimoto, Kanako Suyama, Satoko Sumi, Shirabe Ohki, Kayoko Ogata, Ryota Fujimoto, Daiki Murata, Koichi Nakayama, Kyoko Oka. Creating 3D constructs with cranial neural crest-derived cell lines using a bio-3D printer. Journal of Oral Biosciences. 2024
池口良輔, 青山朋樹, 野口貴志, 吉元孝一, 坂本大地, 岩井輝修, 藤田一晃, 宮崎雄大, 秋枝静香, 中山功一, et al. Bio 3D printerを用いた新しい神経導管. 日本整形外科学会雑誌. 2024. 98. 2. S643-S643
淘江宏文, 池口良輔, 青山朋樹, 野口貴志, 秋枝静香, 中山功一, 松田秀一. これからの人工神経 Bio 3D conduitの現状と今後の展望. 末梢神経. 2023. 34. 2. 220-220
池口良輔, 青山朋樹, 野口貴志, 吉元孝一, 坂本大地, 岩井輝修, 藤田一晃, 秋枝静香, 中山功一, 松田秀一. 創傷治癒に対する再生治療update バイオ3Dプリンターを用いた三次元神経導管による神経再生. 日本創傷治癒学会プログラム・抄録集. 2023. 53回. 50-50
池口良輔, 青山朋樹, 野口貴志, 吉元孝一, 坂本大地, 岩井輝修, 藤田一晃, 秋枝静香, 中山功一, 松田秀一. 創傷治癒に対する再生治療update バイオ3Dプリンターを用いた三次元神経導管による神経再生. 日本創傷治癒学会プログラム・抄録集. 2023. 53回. 50-50

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MISC (74)：

池口良輔, 池口良輔, 青山朋樹, 青山朋樹, 野口貴志, 吉元孝一, 坂本大地, 宮崎雄大, 秋枝静香, 中山功一, et al. 末梢神経損傷に対するバイオ3Dプリンターを用いた三次元神経導管による神経再生. 日本再生医療学会総会(Web). 2024. 23rd
池口良輔, 青山朋樹, 野口貴志, 安藤麻紀, 吉元孝一, 坂本大地, 岩井輝修, 宮崎雄大, 鳥井蓉子, 秋枝静香, et al. 末梢神経損傷に対するバイオ3Dプリンターを用いた三次元神経導管による神経再生. 日本再生医療学会総会(Web). 2023. 22nd
淘江宏文, 池口良輔, 青山朋樹, 野口貴志, 秋枝静香, 中山功一, 松田秀一. Bio 3D conduitの現状と今後の展望. 日本末梢神経学会学術集会プログラム・抄録. 2023. 34th
池口良輔, 青山朋樹, 野口貴志, 吉元孝一, 坂本大地, 岩井輝修, 藤田一晃, 宮崎雄大, 鳥井蓉子, 秋枝静香, et al. バイオ3Dプリンターを用いた三次元神経導管による神経再生治療. 脳循環代謝(Web). 2023. 35. 1
Amamoto S, Itoh M, Takahashi B, Kitsuka T, Uchihashi K, Murata D, Node K, Nakayama K, Kamohara K. Involvement of the PI3K/AKT Pathway in the Formation and Fusion of Spheroids Derived from Human Dermal Fibroblast for Tissue Engineering Technology. Cell and Tissue Biology. 2022. 16. 4. 312-329

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Books (1)：

Kenzan Method for Scaffold-Free Biofabrication
Springer Nature 2021

Education (2)：

- 2005 Kyushu University
- 1997 Kyushu University School of Medicine

Professional career (1)：

M.D.,Ph.D.

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