Tatsunori Nishimura

Affiliation and department：

Research field (1)： Tumor biology

Research keywords (1)： cancer metabolism

Research theme for competitive and other funds (3)：

2019 - 2021 Analyisis of cancer microenvironment under inhibition of enzymes of mitochondrial one-carbon metabolism
2017 - 2019 Evaluation of efficacy for targeting enzymes of mitochondrial one-carbon metabolism for cancer treatment.
2017 - 2019 Evaluation of cancer treatments targeting enzymes of mitochondria one-carbon metabolism

Papers (29)：

Yuming Wang, Tsunaki Hongu, Tatsunori Nishimura, Yasuto Takeuchi, Hiroshi Takano, Takiko Daikoku, Ryoji Yao, Noriko Gotoh. Mitochondrial one-carbon metabolic enzyme MTHFD2 facilitates mammary gland development during pregnancy. Biochemical and biophysical research communications. 2023. 674. 183-189
李梦嬌, 西村建徳, 塩川大介, 矢野正雄, 石川聡子, 太田哲生, 田辺真彦, 多田敬一郎, 秋山徹, 島村徹平, et al. トリプルネガティブ乳がん幹細胞の起源ルミナル前駆細胞は、Na+ポンプFXYD3を利用し抗がん剤耐性を獲得する(FXYD3, a subunit of Na+K+ pump, determines the root of triple-negative breast cancer stem-like cells). 日本癌学会総会記事. 2022. 81回. P-2104
Jin Lee, Xiaoxi Chen, Yuming Wang, Tatsunori Nishimura, Mengjiao Li, Satoko Ishikawa, Takiko Daikoku, Junya Kawai, Arinobu Tojo, Noriko Gotoh. A novel oral inhibitor for one-carbon metabolism and checkpoint kinase 1 inhibitor as a rational combination treatment for breast cancer. Biochemical and Biophysical Research Communications. 2021. 584. 7-14
Yasuto Takeuchi, Natsuko Kimura, Takahiko Murayama, Yukino Machida, Daisuke Iejima, Tatsunori Nishimura, Minoru Terashima, Yuming Wang, Mengjiao Li, Reiko Sakamoto, et al. The membrane-linked adaptor FRS2β fashions a cytokine-rich inflammatory microenvironment that promotes breast cancer carcinogenesis. Proceedings of the National Academy of Sciences. 2021. 118. 43. e2103658118-e2103658118
Reheman Yiming, Yasuto Takeuchi, Tatsunori Nishimura, Mengjiao Li, Yuming Wang, Makiko Meguro-Horike, Takashi Kohno, Shin-ichi Horike, Asuka Nakata, Noriko Gotoh. MUSASHI-2 confers resistance to third-generation EGFR-tyrosine kinase inhibitor osimertinib in lung adenocarcinoma. Cancer Science. 2021

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MISC (6)：

Yasuto Takeuchi, Natsuko Kimura, Takahiko Murayama, Yukino Machida, Daisuke Iejima, Tatsunori Nishimura, Yuming Wang, Mizuki Yamamoto, Naoki Itano, Junichiro Inoue, et al. FRS2b fashions a cytokine-rich inflammatory microenvironment that promotes breast cancer carcinogenesis. CANCER SCIENCE. 2022. 113. 994-994
Li Mengjiao, Tatsunori Nishimura, Daisuke Shiokawa, Shimamura Teppei, Asako Sasahara, Masao Yano, Satoko Ishikawa, Tetsuo Ota, Keiichiro Tada, Koji Okamoto, et al. Single-cell RNAseq identifies subpopulations of drug resistant cancer stem-like cells in patient-derived breast cancer. CANCER SCIENCE. 2022. 113. 1325-1325
Mengjiao Li, Tatsunori Nishimura, Asako Sasahara, Masao Yano, Satoko Ishikawa, Tetsuo Ohta, Kei-ichiro Tada, Daisuke Shiokawa, Koji Okamoto, Noriko Gotoh. Single cell analysis revealed heterogeneity among patient-derived breast cancer stem-like cells. CANCER SCIENCE. 2021. 112. 696-696
Tatsunori Nishimura, Mengjiao Li, Daisuke Shiokawa, Teppei Shimamura, Asako Sasahara, Masao Yano, Satoko Ishikawa, Tetsuo Ohta, Kei-ichiro Tada, Kim Seong-Jin, et al. Identification of subpopulations in patient-derived breast cancer stem-like cells by using RNA sequencing. CANCER SCIENCE. 2021. 112. 173-173
村山貴彦, 西村建徳, 富永香菜, 中田飛鳥, 矢野正雄, 多田敬一郎, 池田和博, 岡本康司, 堀江公仁子, 井上聡, et al. がん関連繊維芽細胞由来液性因子によるがん幹細胞様細胞の維持. 生命科学系学会合同年次大会. 2017. 2017年度. [4P2T26-0944)]

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Books (2)：

乳腺オルガノイド
羊土社 2019
One-carbon metabolism
2016

Professional career (1)：

理学 (筑波大学)

Awards (2)：

日本分子生物学学会優秀ポスター賞
がんと代謝研究会優秀ポスター発表賞

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