SHIRAI TAKAHIRO

シライタカヒロ | SHIRAI TAKAHIRO

Affiliation and department：

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (2)：医薬化学 , 有機化学

Research theme for competitive and other funds (2)：

2021 - 2024 Chain walking制御による不飽和脂肪酸の位置選択的な官能基化反応の開発
2019 - 2021 Selective Synthesis of Regio-isomer of Unsaturated Fatty Acids by Controlling Chain Walking Reaction

Papers (11)：

Midori Kawasaki, Takahiro Shirai, Kenji Yatsuzuka, Ryuichi Shirai. Synthesis of Novel Pseudo-Enantiomeric Phase-Transfer Catalysts from Cinchona Alkaloids and Application to the Hydrolytic Dynamic Kinetic Resolution of Racemic 3-Phenyl-2-oxetanone. Chemical and Pharmaceutical Bulletin. 2024. 72. 10. 913-916
Takahiro Shirai, Shinnosuke Tani, Ryo Nakajima, Takuya Kumamoto. Palladium-Catalyzed Site-Selective Hydrogenation of Unactivated Alkenes Directed by 8-Aminoquinoline Amides. Chemical and Pharmaceutical Bulletin. 2024. 72. 10. 909-912
Takahiro Shirai, Ryo Nakajima, Takuya Kumamoto. Study of Palladium-Catalyzed Site and Regioselective Reductive Heck Hydroarylation of Unactivated Alkene. Chemical and Pharmaceutical Bulletin. 2024. 72. 10. 890-893
Takahiro Shirai, Shinnosuke Tani, Ryo Nakajima, Takuya Kumamoto. Chemoselective Hydrogenation of α,β-Unsaturated Anilides Catalyzed by Palladium-Hydrosilane System. Chemical and Pharmaceutical Bulletin. 2024. 72. 8. 772-774
Takahiro Shirai, Yusuke Migitera, Ryo Nakajima, Takuya Kumamoto. Palladium-Catalyzed Reductive Heck Hydroarylation of Unactivated Alkenes Using Hydrosilane at Room Temperature. The Journal of Organic Chemistry. 2024. 89. 4. 2787-2793

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MISC (3)：

Patents (2)：

Lectures and oral presentations (33)：

ヒドロシランを還元剤とする不活性な二重結合に対する還元的ヘック反応の開発
(第64回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会 2025)
新規シンコナアルカロイド由来キラル相間移動触媒によるトロパ酸β-ラクトンの不斉加水分解
(日本薬学会第145年会 2025)
ヒドロシランを還元剤に用いた温和な不活性アルケンの還元反応の開発
(日本薬学会第145年会 2025)
部位選択的、かつ位置選択的な不活性アルケンの還元的ヘック反応
(日本薬学会第145年会 2025)
ヒドロシランを水素源とする不活性な二重結合の位置選択的な水素化反応の開発
(第63回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会 2024)

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Education (7)：

2025 - 現在広島大学大学院医系科学研究科准教授
2020 - 2025 Hiroshima University
2018 - 2020 Research Foundation Itsuu Laboratory
2015 - 2018 University of tokyo Graduate school of Pharmaceutical Sciences
2015 - 2018 The University of Tokyo Graduate School of Pharmaceutical Sciences Department of Pharmaceutical Sciences

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Work history (2)：

2020/04/01 - 2025/03/31 Hiroshima University Graduate school of Biomedical and Health Sciences Department of Synthetic Organic Chemistry Assistant Professor
2018/04 - 2020/03 Research Foundation ITSUU Laboratory Department of Chemistry Researcher

Committee career (7)：

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Awards (1)：

Association Membership(s) (2)：

THE CHEMICAL SOCIETY OF JAPAN , THE PHARMACEUTICAL SOCIETY OF JAPAN

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