Shinohara Yuta

Affiliation and department：

Research field (3)： Biophysics , Biochemistry , Functional biochemistry

Research theme for competitive and other funds (5)：

2024 - 2029 chronoproteinology
2024 - 2029 Chronoproteinology: post-translational regulatory code counting 24 hours in the circadian clock
2020 - 2024 概日リズムの多重リン酸化を校正する酵素機能解析
2018 - 2020 Creation of autonomously oscillating phosphorylation in the mammalian circadian clock
2013 - 2015 合成生物学的アプローチによる哺乳類概日時計の温度補償性の理解

Papers (18)：

Kazuhiro Kon, Koji L Ode, Tomoyuki Mano, Hiroshi Fujishima, Riina R Takahashi, Daisuke Tone, Chika Shimizu, Shinnosuke Shiono, Saori Yada, Kyoko Matsuzawa, et al. Cortical parvalbumin neurons are responsible for homeostatic sleep rebound through CaMKII activation. Nature communications. 2024. 15. 1. 6054-6054
Yuta Otobe, Eui Min Jeong, Shunsuke Ito, Yuta Shinohara, Nobuhiro Kurabayashi, Atsu Aiba, Yoshitaka Fukada, Jae Kyoung Kim, Hikari Yoshitane. Phosphorylation of DNA-binding domains of CLOCK-BMAL1 complex for PER-dependent inhibition in circadian clock of mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 2024. 121. 23. e2316858121
Ryutaro Furukawa, Masaki Kuwatani, Jing-Jing Jiang, Yuki Tanaka, Rie Hasebe, Kaoru Murakami, Kumiko Tanaka, Noriyuki Hirata, Izuru Ohki, Ikuko Takahashi, et al. GGT1 is a SNP eQTL gene involved in STAT3 activation and associated with the development of Post-ERCP pancreatitis. Scientific reports. 2024. 14. 1. 12224-12224
Kaoru Murakami, Shimpei I Kubota, Kumiko Tanaka, Hiroki Tanaka, Keiichiroh Akabane, Rigel Suzuki, Yuta Shinohara, Hiroyasu Takei, Shigeru Hashimoto, Yuki Tanaka, et al. High-precision rapid testing of omicron SARS-CoV-2 variants in clinical samples using AI-nanopore. Lab on a chip. 2023. 23. 22. 4909-4918
Reiji Yamamoto, Satoshi Yamada, Toru Atsumi, Kaoru Murakami, Ari Hashimoto, Seiichiro Naito, Yuki Tanaka, Izuru Ohki, Yuta Shinohara, Norimasa Iwasaki, et al. Computer model of IL-6-dependent rheumatoid arthritis in F759 mice. International immunology. 2023. 35. 9. 403-421

ｍore...

Lectures and oral presentations (3)：

Timekeepers of the mammalian circadian clock regulate post-translational modifications.
(2023)
Design principles of temperature-compensated phosphorylation in the circadian clock.
(New Frontier in Protein Design & Engineering 2019)
Design principles of temperature-compensated phosphorylation in the mammalian circadian clock.
(2018)

Professional career (1)：

博士(工学) (大阪大学)

Work history (5)：

2021/10 - 現在 Hokkaido University Institute for Genetic Medicine
2018/04 - 2021/09 RIKEN
2015/04 - 2018/03 理化学研究所生命システム研究センター特別研究員
2013/04 - 2015/03 日本学術振興会特別研究員(DC2)
2012/04 - 2013/03 理化学研究所大学院生リサーチアソシエイト

Awards (3)：

2018/06 - 日本蛋白質科学会若手奨励賞
2018/03 - 理化学研究所研究奨励賞
2017/10 - 日本時間生物学会学術大会優秀ポスター賞

Association Membership(s) (4)：

THE BIOPHYSICAL SOCIETY OF JAPAN , THE JAPANESE BIOCHEMICAL SOCIETY , PROTEIN SCIENCE SOCIETY OF JAPAN , JAPANESE SOCIETY FOR CHRONOBIOLOGY

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