Research theme for competitive and other funds (10):
2023 - 2027 Novel pathogenesis and therapeutic strategy of autoimmunity based on immune-tuning molecules
2022 - 2025 免疫細胞フェノタイプによるシェーグレン症候群の個別化医療の構築
2020 - 2021 シェーグレン症候群に対する病期・病態対応型シームレス医療の構築
2019 - 2021 JAK/STATシグナル制御を標的としたシェーグレン症候群の新規治療戦略
2017 - 2020 疾患関連分子群の発現制御を基盤とするシェーグレン症候群治療法の開発
2015 - 2018 IP-10 を分子標的としたシェーグレン症候群の新規診断・治療法の開発
2012 - 2014 Salivary gland regeneration by anti-TNF regents
2009 - 2011 Sensitivity diagnosis of molecular target drugs for oral cancer
2007 - 2009 Apply to imatinib in oral cancer treatment
2007 - 2009 Analysis of Wnt signal pathway in the invasion and metastasis of oral squamous carcinoma cells and application to molecule target therapy
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Papers (85):
Keiko Aota, Koichi Kani, Shinji Ono, Kohei Naniwa, Yukihiro Momota, Makoto Fukui, Naozumi Ishimaru, Masayuki Azuma. Activation of Janus kinase 2 contributes to the autoimmune pathology in the salivary glands of patients with Sjögren's syndrome. Oral Science International. 2024
Keiko Aota. Medical and Oral Care in the 21st Century by the Department of Oral Medicine - A novel Therapeutic Strategy for Dry Mouth on the Basis of Molecular Mechanisms Involved in the Onset of the Disease -. Journal of Oral Health and Biosciences. 2024. 36. 2. 13-21
Tetsu Shimane, Kazuyuki Koike, Shigeyuki Fujita, Hiroshi Kurita, Emiko Tanaka Isomura, Daichi Chikazu, Naomi Kanno, Keiichi Sasaki, Satoshi Hino, Hideharu Hibi, et al. Positive impact of perioperative oral management on the risk of surgical site infections after abdominal surgery: Sixteen universities in Japan. Medicine. 2023. 102. 37. e35066-e35066
Shakya Supriya, Ryoko Ushikoshi-Nakayama, Tomoe Yamazaki, Daisuke Omagari, Keiko Aota, Hiroko Inoue, Naoyuki Matsumoto, Ichiro Saito. Effects of polyphenols in non-centrifugal cane sugar on saliva secretion: in vitro and in vivo experiments and a randomized controlled trial. Journal of clinical biochemistry and nutrition. 2023. 72. 2. 171-182
日本口腔ケア学会
, 日本口腔腫瘍学会
, 日本頭頸部癌学会
, The Japanese Cancer Association
, Japanese Stomatological Society
, Japanese Society of Oral and Maxillofacial Surgeons