Rchr
J-GLOBAL ID:201801008035174132   Update date: Jun. 14, 2021

Kimura Hirokazu

Kimura Hirokazu
Research field  (2): Pathobiochemistry ,  Tumor biology
Research theme for competitive and other funds  (3):
  • 2018 - 2020 細胞膜受容体CKAP4のエクソソームへの輸送メカニズムと生理機能の解析
  • 2018 - 2019 抗CKAP4抗体を基軸とした新規がん治療法の開発
  • 2016 - 2018 Analysis of the translocation mechanism of CKAP4 to exosome
Papers (17):
  • Hirokazu Kimura, Ryota Sada, Naoki Takada, Akikazu Harada, Yuichiro Doki, Hidetoshi Eguchi, Hideki Yamamoto, Akira Kikuchi. The Dickkopf1 and FOXM1 positive feedback loop promotes tumor growth in pancreatic and esophageal cancers. Oncogene. 2021
  • Ryota Sada, Hirokazu Kimura, Yuko Fukata, Masaki Fukata, Hideki Yamamoto, Akira Kikuchi. Dynamic palmitoylation controls the microdomain localization of the DKK1 receptors CKAP4 and LRP6. Science signaling. 2019. 12. 608
  • Hirokazu Kimura, Hideki Yamamoto, Takeshi Harada, Katsumi Fumoto, Yoshihito Osugi, Ryota Sada, Natsumi Maehara, Hayato Hikita, Soichiro Mori, Hidetoshi Eguchi, et al. CKAP4, a DKK1 Receptor, Is a Biomarker in Exosomes Derived from Pancreatic Cancer and a Molecular Target for Therapy. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019. 25. 6. 1936-1947
  • Takeshi Harada, Shinji Matsumoto, Suguru Hirota, Hirokazu Kimura, Shinsuke Fujii, Yuuya Kasahara, Hidetoshi Gon, Toshihiko Yoshida, Tomoo Itoh, Naotsugu Haraguchi, et al. Chemically Modified Antisense Oligonucleotide Against ARL4C Inhibits Primary and Metastatic Liver Tumor Growth. Molecular cancer therapeutics. 2019. 18. 3. 602-612
  • Kajiwara C, Fumoto K, Kimura H, Nojima S, Asano K, Odagiri K, Yamasaki M, Hikita H, Takehara T, Doki Y, et al. p63-dependent Dickkopf3 expression promotes esophageal cancer cell proliferation via CKAP4. Cancer Research. 2018
more...
MISC (61):
Professional career (1):
  • 博士(医学) (大阪大学)
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page