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J-GLOBAL ID:201801008049373758   Update date: Jan. 30, 2024

Tanihara Fuminori

Tanihara Fuminori
Affiliation and department:
Research field  (1): Zoological sciences
Research keywords  (4): oocyte ,  gene editing ,  in vitro fertilization ,  pig
Research theme for competitive and other funds  (7):
  • 2022 - 2026 慢性腎臓病に起因する健康寿命減衰をリン(CPP)の除去により防ぎ止める橋渡し研究
  • 2021 - 2026 Generation of African Swine Fever virus-resistant pigs by applying the concept of gene editing technology
  • 2018 - 2023 気道・肺の障害・修復と再生におけるp53の役割~p53遺伝子改変ブタを用いた研究
  • 2019 - 2021 Generation of a pig model for the diabetic nephropathy using gene editing technology
  • 2018 - 2021 Production of immunodeficient micro-mini pig using genome editing technology.
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Papers (100):
  • Fuminori Tanihara, Maki Hirata, Zhao Namula, Manita Wittayarat, Lanh Thi Kim Do, Qingyi Lin, Koki Takebayashi, Hiromasa Hara, Megumi Nagahara, Takeshige Otoi. GHR-mutant pig derived from domestic pig and microminipig hybrid zygotes using CRISPR/Cas9 system. Molecular biology reports. 2023. 50. 6. 5049-5057
  • Thanh Van Nguyen, Lanh Thi Kim Do, Zhao Namula, Qingyi Lin, Nanaka Torigoe, Megumi Nagahara, Maki Hirata, Fuminori Tanihara, Takeshige Otoi. DEVELOPMENT AND GENOME MUTATION OF BOVINE ZYGOTES VITRIFIED BEFORE AND AFTER GENOME EDITING VIA ELECTROPORATION. Cryo-Letters. 2023. 44. 2. 118-122
  • Fuminori Tanihara, Maki Hirata, Zhao Namula, Lanh Thi Kim Do, Naoaki Yoshimura, Qingyi Lin, Koki Takebayashi, Tetsushi Sakuma, Takashi Yamamoto, Takeshige Otoi. Pigs with an INS point mutation derived from zygotes electroporated with CRISPR/Cas9 and ssODN. Frontiers in cell and developmental biology. 2023. 11. 884340
  • Fuminori Tanihara, Maki Hirata, Takeshige Otoi. GEEP Method: An Optimized Electroporation-Mediated Gene Editing Approach for Establishment of Knockout Pig Lines. Methods in molecular biology (Clifton, N.J.). 2023. 2637. 293-300
  • Koki Takebayashi, Manita Wittayarat, Qingyi Lin, Nanaka Torigoe, Bin Liu, Maki Hirata, Megumi Nagahara, Fuminori Tanihara, Takeshige Otoi. Efficiency of genetic modification in gene-knockout sperm-derived zygotes followed by electroporation of guide RNA targeting the same gene. Animal science journal = Nihon chikusan Gakkaiho. 2023. 94. 1. e13842
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MISC (7):
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Patents (1):
  • Cas9タンパク質を哺乳動物の受精卵に導入する方法
Professional career (1):
  • 博士(獣医学) (山口大学)
Work history (1):
  • 2020/10 - 現在 Jichi Medical University
Association Membership(s) (6):
THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE ,  SOCIETY FOR REPRODUCTION AND DEVELOPMENT ,  International Society for Transgenic Technologies ,  日本異種移植研究会 ,  日本ゲノム編集学会 ,  日本獣医学会
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