Rchr
J-GLOBAL ID：201801008054519906   Update date: Nov. 20, 2024

Momoka Yamaguchi

ヤマグチ モモカ | Momoka Yamaguchi
Affiliation and department：
University of Shizuoka School of Pharmaceutical Sciences

About University of Shizuoka School of Pharmaceutical Sciences


Research field  (1)： Pharmacology
Research keywords  (6)： 薬理学 ,  肝線維化 ,  NASH ,  肝星細胞 ,  ブレス・プリント ,  肝類洞血流
Research theme for competitive and other funds  (15)：
  • 2024 - 2029 膵肝連関に着目した高血糖によるNASH 進展トリガーシグナルの解明
  • 2024 - 2028 筋線維芽細胞様肝星細胞を標的とするMASH治療薬開発に向けた細胞内シグナルスイッチ機構の解明
  • 2024 - 2027 ヒト呼気中揮発性有機物の構成解析に基づく肝線維化簡易診断法の確立に向けた基盤研究
  • 2023 - 2026 肝星細胞における液-液相分離を標的としたNASH進行スイッチ制御の確立
  • 2022 - 2025 NASH進行のスイッチとなる肝実質細胞-肝星細胞間相互作用制御の分子機構
Show all
Papers (14)：
  • Naoki Dohi, Momoka Yamaguchi, Kyosuke Iwami, Yukiko K. Kaneko, Shin-ya Saito, Tomohisa Ishikawa. Mouse liver blood flow is regulated by hepatic stellate cells in response to the sympathetic neurotransmitter norepinephrine. Life Sciences. 2024. 359. 123214-123214
  • Takayuki Oguma, Takanori Kanazawa, Yukiko K Kaneko, Ren Sato, Miku Serizawa, Akira Ooka, Momoka Yamaguchi, Tomohisa Ishikawa, Hiromu Kondo. Effects of phospholipid type and particle size on lipid nanoparticle distribution in vivo and in pancreatic islets. Journal of controlled release : official journal of the Controlled Release Society. 2024
  • Soshiro Kodera, Toshihide Kimura, Tomoki Nishioka, Yukiko K Kaneko, Momoka Yamaguchi, Kozo Kaibuchi, Tomohisa Ishikawa. GDP-bound Rab27a regulates clathrin disassembly through HSPA8 after insulin secretion. Archives of biochemistry and biophysics. 2023. 749. 109789-109789
  • Mai Kato, Momoka Yamaguchi, Akira Ooka, Ryota Takahashi, Takuji Suzuki, Keita Onoda, Yuko Yoshikawa, Yuta Tsunematsu, Michio Sato, Yasukiyo Yoshioka, et al. Non-target GC-MS analyses of fecal VOCs in NASH-hepatocellular carcinoma model STAM mice. Scientific reports. 2023. 13. 1. 8924-8924
  • Megumi Kaji, Yukiko K Kaneko, Stella Amarachi Ihim, Ran Kanoh, Moe Yamamoto, Momoka Yamaguchi, Tomohisa Ishikawa. Oral ingestion of Shiikuwasha extract suppresses diabetes progression in db/db mice by preserving β-cell mass. Frontiers in nutrition. 2023. 10. 1336133-1336133
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MISC (22)：
  • 柴田涼吾, 金子雪子, 山口桃生, 森野純鈴, 金沢貴憲, 石川智久. 植物由来エキソソーム様ナノ粒子が膵β細胞アポトーシスに及ぼす影響の検討. 日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会講演要旨集. 2023. 2023
  • 芹澤未来, 金沢貴憲, 金沢貴憲, 金子雪子, 佐藤蓮, 大岡央, 山口桃生, 飯岡真吾, 尾熊貴之, 石川智久, et al. 静脈投与による脂質ナノ粒子の膵島分布特性に及ぼすリン脂質および粒子径の影響. 日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会講演要旨集. 2023. 2023
  • 森野純鈴, 山口桃生, 岡部磨幸, 河合佑美, 金子雪子, 柴田涼吾, 大岡央, 金沢貴憲, 石川智久. 植物由来エキソソーム様ナノ粒子が肝星細胞の活性化制御および細胞への取り込みに及ぼす影響. 生体膜と薬物の相互作用シンポジウム講演要旨集. 2023. 44th
  • 岡部磨幸, 山口桃生, 大岡央, 森野純鈴, 柴田涼吾, 金沢貴憲, 金子雪子, 石川智久. Effects of plant-derived exosome-like nanoparticles on the activation of hepatic stellate cells. 日本薬学会年会要旨集(Web). 2023. 143rd
  • 柴田涼吾, 金子雪子, 山口桃生, 森野純鈴, 金沢貴憲, 石川智久. 膵β細胞アポトーシスに対する植物由来エキソソーム様ナノ粒子の効果の検証. 次世代を担う若手のための創薬・医療薬理シンポジウムプログラム・要旨集. 2023. 2023
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Lectures and oral presentations  (12)：
  • Treatment of hepatocytes with palmitic acid induces the release of extracellular vesicles with tropism to activated hepatic stellate cells
    (23rd International Conference on Cytochrome P450 (ICCP450) and the 38th Annual Meeting of the Japanese Society for the Study of Xenobiotics (JSSX) (2023 ICCP450/JSSX International Joint meeting) 2023)
  • Analysis of the mechanism underlying the DIF-1 effect on HSCs transdifferentiation
    (19th World Congress of Basic & Clinical Pharmacology 2023 2023)
  • Inhibition of adenosine receptors induces the inversion of prostaglandin E2 effects on hepatic stellate cell
    (19th World Congress of Basic & Clinical Pharmacology 2023 2023)
  • Caffeine induces the reversion of activated hepatic stellate cells via antagonizing adenosine receptors
    (2020)
  • Hepatic stellate cells contract and regulate sinusoidal blood flow in response to the sympathetic neurotransmitter, noradrenaline.
    (50th NIPS international symposium 2019)
ｍore...
Education (3)：
  • 2013 - 2017 University of Shizuoka
  • 2011 - 2013 University of Shizuoka Graduate School of Pharmaceutical Sciences
  • 2007 - 2011 University of Shizuoka School of Pharmaceutical Sciences
Professional career (1)：
  • 博士号(薬科学) (静岡県立大学)
Work history (1)：
  • 2017/04 - 現在 University of Shizuoka School of Pharmaceutical Sciences
Awards (2)：
  • 2024/07 - 日本薬学会東海支部 令和6年度東海支部学術奨励賞
  • 2023/12 - 静岡県立大学 学長表彰 教員活動評価における業績優秀者
Association Membership(s) (4)：
Shizuoka Experimental Animal Research Association ,  THE JAPANESE SOCIETY FOR THE RESEARCH OF HEPATIC CELLS ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE JAPANESE PHARMACOLOGICAL SOCIETY
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