Rchr
J-GLOBAL ID:201801008500448929   Update date: Nov. 17, 2024

Hikosaka-kuniishi Mari

クニイシ マリ | Hikosaka-kuniishi Mari
Affiliation and department:
Job title: Assistant Professor
Homepage URL  (2): http://www.pha.u-toyama.ac.jp/research/laboratory/cellbiol/http://www.pha.u-toyama.ac.jp/en/research/laboratory/cellbiol/
Research field  (1): Immunology
Research keywords  (10): germinal center ,  TACI ,  TRAF5 ,  CD40 ,  stromal cell ,  lymph node ,  IgA ,  follicular dendritic cells ,  IgE ,  allergy
Research theme for competitive and other funds  (3):
  • 2022 - 2025 I型アレルギー疾患の制御にむけたFDCによるIgA抗体の産生制御機構の基礎的研究
  • 2019 - 2022 Follicular dendritic cellによるIgE産生制御機構の解明
  • 2017 - 2019 The mechanisms about the cell aggregation of IgE-producing cells
Papers (14):
  • Mari Hikosaka-Kuniishi, Chieri Iwata, Yusuke Ozawa, Sayaka Ogawara, Tomomi Wakaizumi, Riho Itaya, Ren Sunakawa, Ayaka Sato, Hodaka Nagai, Masashi Morita, et al. The Role of TNF Receptor-Associated Factor 5 in the Formation of Germinal Centers by B Cells During the Primary Phase of the Immune Response in Mice. Int. J. Mol. Sci. 2024. 25. 22. 12331
  • Doris Narki Tetteh, Kana Isono, Mari Hikosaka-Kuniishi, Hidetoshi Yamazaki. Neural Crest-Derived Mesenchymal Cells Support Thymic Reconstitution After Lethal Irradiation. European journal of immunology. 2024. e202451305
  • Naoki Tsunokuma, Doris Narki Tetteh, Kana Isono, Mari Kuniishi-Hikosaka, Motokazu Tsuneto, Kenichiro Ishii, Hidetoshi Yamazaki. Depletion of Neural Crest-Derived Cells Leads to Plasma Noradrenaline Decrease and Alters T Cell Development. The Journal of Immunology. 2023. 211. 10. 1494-1505
  • Hodaka Nagai, Mitsuki Azuma, Ayaka Sato, Nagito Shibui, Sayaka Ogawara, Yuta Tsutsui, Ayano Suzuki, Tomomi Wakaizumi, Aya Ito, Shimpei Matsuyama, et al. Fundamental Characterization of Antibody Fusion-Single-Chain TNF Recombinant Proteins Directed against Costimulatory TNF Receptors Expressed by T-Lymphocytes. Cells. 2023. 12. 12
  • Mari Hikosaka Kuniishi, Naoto Ishii, Takanori So. Role of tumor necrosis factor receptor-associated factor 5 in B- and T-lymphocytes. Exploration of Immunology. 2023. 40-55
more...
MISC (10):
  • 佐藤綾香, 東充輝, 永井穂高, 鈴木綾乃, 伊藤文, 守田雅志, 國石(彦坂)茉里, 宗孝紀. Structural and functional characterization of OX40 ligand proteins that regulate TNF receptor family molecule OX40 expressed by T-lymphocytes. 日本薬学会年会要旨集(Web). 2024. 144th
  • 東充輝, 斉藤弘晃, 若泉知美, 岩谷航洋, 小澤勇介, 守田雅志, 國石(彦坂)茉里, 宗孝紀. Does the higher levels of TRAF5 play an important role for suppression of TLR-driven Immunoglobulin M antibody production from B cells?. 日本薬学会年会要旨集(Web). 2024. 144th
  • 守田雅志, 松沢紗良, 國石(彦坂)茉里, 宗孝紀. Hyperactivation of NLRP3 inflammasome in ABCD1-deficient human astrocytoma U87 cells. 日本薬学会年会要旨集(Web). 2024. 144th
  • 國石(彦坂)茉里, 筒井雄太, 小林奏一朗, 東充輝, 真柄弘汰, 小河原さやか, 岩田千恵梨, 若泉知美, 守田雅志, 宗孝紀. The role of Traf5 in the IgA production by mouse mucosal tissues. 日本薬学会年会要旨集(Web). 2024. 144th
  • 東充輝, 斉藤弘晃, 岩谷航洋, 若泉知美, 今井若菜, 守田雅志, 國石(彦坂)茉里, 宗孝紀. Analysis of negative regulatory function of TRAF5 for immune cell receptors. 日本薬学会年会要旨集(Web). 2023. 143rd
more...
Lectures and oral presentations  (21):
  • TNF receptor-associated factor 5 promotes antibody production and germinal center formation mediated by CD40
    (The 1st Annual Meeting of the Japanese Cytokine Society (JCS2024) 2024)
  • Follicular dendritic cell-mediated enhancement of the differentiation into IgA+GL7+ cells
    (The 50th Annual Meeting of the Japanese Society for Immunology 2021)
  • エナメル質形成不全マウス(Amelx♂)及び象牙質形成不全マウス(DsppGFP/GFP)を用いたエナメル質及び象牙質の構造解析の試み
    (第2回 Winter Dental Meeting in Tsu(ウインターデンタルミーティングin津) 2021)
  • リンパ節ストローマ細胞 Follicular dendritic cellによるレチノイン酸を介したIgA 抗体制御機序の解明への試み
    (第2回 Winter Dental Meeting in Tsu(ウインターデンタルミーティングin津) 2021)
  • Amelx欠損及びDspp遺伝子欠損マウスの歯のCT解析
    (第48回三重歯科・口腔外科学会 2020)
more...
Education (4):
  • 2014 - 2017 Tottori University Graduate School of Medical Sciences
  • 2012 - 2014 Tottori University Graduate School of Medical Sciences
  • 2008 - 2012 Tottori University Faculty of Medicine School of Life Sciences
  • - 2008 広島大学附属福山高等学校
Professional career (1):
  • 博士(生命科学) (鳥取大学)
Work history (1):
  • 2017/04 - 2022/07 Mie University Graduate School of Medicine Department of Stem Cell and Developmental Biology
Awards (4):
  • 2016/12 - 日本免疫学会 Tadamitsu Kishimoto International Travel Award
  • 2016/02 - 鳥取大学大学院 鳥取大学大学院エンカレッジ・ファンド
  • 2015/02 - 鳥取大学大学院 鳥取大学大学院エンカレッジ・ファンド
  • 2014/12 - 日本免疫学会 Ursula and Fritz Melchers Travel Award
Association Membership(s) (3):
日本サイトカイン学会 ,  日本薬学会 ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY
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