Wakuda Tomoyasu

ワクダトモヤス | Wakuda Tomoyasu

Affiliation and department：
Job title： Senior Assistant Professor

Research keywords (6)：統合失調症 , 自閉スペクトラム症 , 脳画像 , 分子精神医学 , neuroinflammation , ミクログリア

Research theme for competitive and other funds (13)：

2024 - 2027 活性化ミクログリアへの作用に着目した自閉スペクトラム症オキシトシン治療機序の解明
2020 - 2023 Multi-layer illustration of neuronal viability and microglial polarization in Alzheimer's disease
2020 - 2023 Exploration of serotonin-oxytocin interaction: Development of novel therapy on autism.
2019 - 2023 Involvement of alpha7 nicotinic acetylcholine receptors and neuroinflammation in the self-medicating effects of smoking in individuals with schizophrenia
2017 - 2020 In vivo imaging for pathological substance and neuroinflammation/neuroactivity and therapeutic strategy in Alzheimer's disease

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Papers (33)：

Tomoyasu Wakuda, Seico Benner, Yukari Uemura, Tomoko Nishimura, Masaki Kojima, Miho Kuroda, Kaori Matsumoto, Chieko Kanai, Naoko Inada, Taeko Harada, et al. Oxytocin-induced increases in cytokines and clinical effect on the core social features of autism: Analyses of RCT datasets. Brain, behavior, and immunity. 2024. 118. 398-407
Yasuhiko Kato, Masamichi Yokokura, Toshiki Iwabuchi, Chihiro Murayama, Taeko Harada, Takafumi Goto, Taishi Tamayama, Yosuke Kameno, Tomoyasu Wakuda, Hitoshi Kuwabara, et al. Lower Availability of Mitochondrial Complex I in Anterior Cingulate Cortex in Autism: A Positron Emission Tomography Study. The American journal of psychiatry. 2023. 180. 4. 277-284
Itaru Kushima, Masahiro Nakatochi, Branko Aleksic, Takashi Okada, Hiroki Kimura, Hidekazu Kato, Mako Morikawa, Toshiya Inada, Kanako Ishizuka, Youta Torii, et al. Cross-Disorder Analysis of Genic and Regulatory Copy Number Variations in Bipolar Disorder, Schizophrenia, and Autism Spectrum Disorder. Biological psychiatry. 2022. 92. 5. 362-374
Hidenori Yamasue, Masaki Kojima, Hitoshi Kuwabara, Miho Kuroda, Kaori Matsumoto, Chieko Kanai, Naoko Inada, Keiho Owada, Keiko Ochi, Nobutaka Ono, et al. Effect of a novel nasal oxytocin spray with enhanced bioavailability on autism: a randomized trial. Brain : a journal of neurology. 2022. 145. 2. 490-499
Chihiro Murayama, Toshiki Iwabuchi, Yasuhiko Kato, Masamichi Yokokura, Taeko Harada, Takafumi Goto, Taishi Tamayama, Yosuke Kameno, Tomoyasu Wakuda, Hitoshi Kuwabara, et al. Extrastriatal dopamine D2/3 receptor binding, functional connectivity, and autism socio-communicational deficits: a PET and fMRI study. Molecular psychiatry. 2022. 27. 4. 2106-2113

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MISC (9)：

和久田智靖, 中村佳夏, 横倉正倫, 加藤康彦, 竹林淳和. COVID-19大流行前後における浜松医科大学医学部附属病院の摂食障害入院患者数の推移. 日本児童青年精神医学会総会抄録(Web). 2023. 64th
和久田智靖, 横倉正倫, 中泉享子, 加藤康彦, 亀野陽亮, 桑原斉, 二ツ橋昌実, 吉川悦次, 間賀田泰寛, 尾内康臣, et al. 統合失調症におけるα7ニコチン性アセチルコリン受容体 [11C](R)-MeQAAを用いたPET脳画像の予備的研究. 精神神経学雑誌. 2019. 2019特別号. S470-S470
和久田智靖. Approach to treatment of psychiatric symptoms and involuntary movements in patients with anti-NMDA receptor encephalitis. 臨床精神薬理. 2017. 20. 4. 399-406
和久田智靖. 神経発達障害仮説に基づく統合失調症動物モデルからみた予防. 日本精神保健・予防学会学術集会プログラム・抄録集. 2015. 19th
和久田智靖, 栗田大輔, 竹林淳和, 岩田泰秀, 鈴木勝昭, 森則夫. 神経性無食欲症患者に対する身体管理マニュアルの心理的影響と副次的効果. 日本摂食障害学会学術集会プログラム・講演抄録集. 2014. 18th

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Work history (4)：

2016/02 - 現在 Hamamatsu University School of Medicine University Hospital
2010/12 - 2016/01 Hamamatsu University School of Medicine School of Medicine, Faculty of Medicine
2009/07 - 2010/11 Hamamatsu University School of Medicine University Hospital
2009/04 - 2009/06 Hamamatsu University School of Medicine University Hospital

Committee career (2)：

2021/11 - 現在日本総合病院精神医学会有床総合病院精神科委員
2019/06 - 現在日本生物学的精神医学会評議員

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