Iemura Kenji

イエムラケンジ | Iemura Kenji

Affiliation and department：
Job title： Assistant Professor

Research field (4)： Tumor biology , Genetics , Cell biology , Molecular biology

Research keywords (7)： Chromosomal instability , Cell devision , Cancer , Cell cycle , Mitosis , Chromosome , Chromosome segregation

Research theme for competitive and other funds (13)：

2023 - 2026 Mechanisms of chromosomal instability induction via extracellular factors
2023 - 2024 老化細胞における染色体不安定性発生機構の解明
2021 - 2024 Elucidation of the mechanism of cell-to-cell transmission of chromosomal instability
2021 - 2022 染色体不安定性がん細胞の増殖優位性獲得機構を抑制する薬理活性化合物の探索
2020 - 2022 Elucidation of the molecular mechanism required for the acquisition of growth advantage in CIN cancer cell

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Papers (24)：

Go Itoh, Yuma Fukushi, Kurara Takagane, Keisuke Kanetaka, Hitomi Suzuki, Yohei Kawasaki, Sei Kuriyama, Kenji Iemura, Kozo Tanaka, Akiteru Goto, et al. Effects of mitotically active polyploid giant cancer cells on chemoresistance through interaction with cancer-associated fibroblasts. British Journal of Cancer. 2025
Kailin Zhu, Guan Chen, Yueyi Ren, Kenji Iemura, Kozo Tanaka. Human fibroblasts from aged individuals exhibit chromosomal instability through replication stress caused by oxidative stress. npj Aging. 2025
Yujiro Yoshizaki, Yunosuke Ouchi, Dicky Kurniawan, Eisuke Yumoto, Yuki Yoneyama, Faiza Ramadhani Rizqullah, Hiyori Sato, Mirjam Hanako Sarholz, Toyoaki Natsume, Masato T Kanemaki, et al. CHAMP1 premature termination codon mutations found in individuals with intellectual disability cause a homologous recombination defect through haploinsufficiency. Scientific reports. 2024. 14. 1. 31904-31904
Sharmin Naher, Kenji Iemura, Satoshi Miyashita, Mikio Hoshino, Kozo Tanaka, Shinsuke Niwa, Jin-Wu Tsai, Takako Kikkawa, Noriko Osumi. Kinesin-like motor protein KIF23 maintains neural stem and progenitor cell pools in the developing cortex. The EMBO Journal. 2024. 44. 2. 331-355
Kenji Iemura, Kozo Tanaka. Assessment of Chromosome Oscillations in Mammalian Cells by Live Cell Imaging. Methods in Molecular Biology. 2024. 157-164

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MISC (50)：

湯本瑛亮, 家村顕自, 朽津芳彦, 田口友彦, 田中耕三. がん細胞における自然免疫分子STINGの分解依存的な制御機構の解明. 日本生化学会大会(Web). 2024. 97th
家村顕自, 田中耕三. がん細胞液性因子を介した染色体不安定性誘導機構(Mechanisms of CIN induction via cancer extracellular factors). 日本癌学会総会記事. 2023. 82回. 1136-1136
家村顕自, 田中耕三. 染色体不安定性に対するがん細胞の生存戦略(Survival strategies of cancer cells against chromosomal instability). 日本癌学会総会記事. 2022. 81回. J-1033
家村顕自, 田中耕三. 染色体分配における染色体オシレーションの役割. 生化学. 2022. 94. 3. 433-437
家村顕自, 田中耕三. Cancer secretome induces chromosomal instability. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th

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Lectures and oral presentations (3)：

Education (2)：

2009 - 2012 The University of Tokyo Graduate schools of Science
2007 - 2009 Nagahama Institute of Bio-Science and Technology Graduate schools of Bioscience

Professional career (1)：

Work history (6)：

2024/02 - 現在 Tohoku University
2016/02 - 現在 Tohoku University Institute of Development, Aging and Cancer Division of Cancer Control
2012/08 - 2016/01 Institute of Development, Aging and Cancer, Tohoku University
2012/05 - 2012/07 Institute of Development, Aging and Cancer, Tohoku University
2012/04 - 2012/05 The Institute of Medical Science, The University of Tokyo

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Committee career (1)：

Awards (5)：

Association Membership(s) (4)：

日本生化学会 , 日本細胞生物学会 , 日本癌学会 , 日本分子生物学会

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