Rchr
J-GLOBAL ID：201801009158622713   Update date: Jul. 16, 2024

Iribe Gentaro

イリベ ゲンタロウ | Iribe Gentaro
Affiliation and department：
Asahikawa Medical University Department of Physiology, Division of Integrative Cardiovascular Sciences

About Asahikawa Medical University Department of Physiology, Division of Integrative Cardiovascular Sciences


Job title： Professor
Research field  (2)： Clinical pharmacy ,  Physiology
Research keywords  (4)： mechano-electric coupling ,  心臓力学 ,  mechano-electric coupling ,  cardiac mechanics
Research theme for competitive and other funds  (25)：
  • 2021 - 2024 新規メカニカル負荷装置の開発を通した次世代メカノメディスンへの挑戦
  • 2021 - 2024 Force-Length Relationによる単離ヒト心筋細胞の機能評価
  • 2021 - 2024 心筋機械感受性制御におけるROSシグナリングの役割とその心不全治療への展開
  • 2020 - 2023 Investigation of NOX4-mediated mechanotransduction in mechanically-induced cardiac failure
  • 2017 - 2020 Physiological and pathophysiological role of NOX4 in cardiac mechano-transduction
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Papers (73)：
  • Komatsu Hiroaki, Kotani Yasuhiro, Kaihara Keiko, Naruse Keiji, Kasahara Shingo, Iribe Gentaro. Single cell mechanics of human cardiomyocytes assessed by cellular force-length relationships(タイトル和訳中). The Journal of Physiological Sciences. 2023. 73. Suppl.1. 108-108
  • Keiko Kaihara, Hiroaki Kai, Yumiko Chiba, Keiji Naruse, Gentaro Iribe. Stretch-induced reactive oxygen species contribute to the Frank-Starling mechanism. The Journal of Physiology. 2023
  • Yamaguchi Yohei, Kaneko Toshiyuki, Iribe Gentaro, Ohya Susumu. Myocardial TRPC6 modulates stretch-induced increase in contractility via Zn2+ mobilization. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2023. 97. 2-B-P-006
  • Kaihara Keiko, Naruse Keiji, Iribe Gentaro. マウス心室心筋細胞におけるNOX4-TRPV1相互作用の単一細胞力学に対する役割(Role of NOX4-TRPV1 interaction on single cell mechanics in mouse ventricular cardiomyocytes). The Journal of Physiological Sciences. 2022. 72. Suppl.1. 117-117
  • Sayaka Oda, Kazuhiro Nishiyama, Yuka Furumoto, Yohei Yamaguchi, Akiyuki Nishimura, Xiaokang Tang, Yuri Kato, Takuro Numaga-Tomita, Toshiyuki Kaneko, Supachoke Mangmool, et al. Myocardial TRPC6-mediated Zn2+ influx induces beneficial positive inotropy through β-adrenoceptors. Nature communications. 2022. 13. 1. 6374-6374
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MISC (28)：
  • KAIHARA Keiko, NARUSE Keiji, IRIBE Gentaro. Involvement of myocardial acute stretch-induced ROS production in development of heart failure. 日本生体医工学会大会プログラム・抄録集(Web). 2020. 59th
  • KAIHARA Keiko, IRIBE Gentaro, KAI Hiroaki, NARUSE Keiji. Single cell mechanics effects of NADPH oxidase (NOX) 4 in mouse ventricular cardiomyocytes. 生物物理(Web). 2018. 58. Supplement 1-2
  • Takahashi K, Oh H, Iribe G, Matsuura K, Naruse K. Application of mechanobiological engineering to regenerative and reproductive medicine. Trans JSMBE. 2017. 55. 4PM-Abstract. 340
  • Anastasia Khokhlova, Gentaro Iribe, Olga Solovyova. Transmural Differences in Preload-Dependency of CA(2+) Transients in Isolated Cardiomyocytes. BIOPHYSICAL JOURNAL. 2016. 110. 3. 99A-99A
  • 貝原恵子, 成瀬恵治, 入部玄太郎. 伸展刺激誘発性カルシウムスパーク増加におけるミトコンドリアの役割. 日本生理学雑誌. 2014. 76. 4 (Web)
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Books (4)：
  • Biological, Physical and Technical Basics of Cell Engineering.
    Springer 2018
  • Cardiac mechano-electric coupling and arrhythmias. 2nd edition
    Oxford University Press 2011
  • バイオテクノロジーシリーズ 細胞分離・操作技術の最前線
    (株)シーエムシー 2008
  • 細胞分離・操作技術の最前線
    シーエムシー出版 2008
Lectures and oral presentations  (30)：
  • Application of mechanobiological engineering to regenerative and reproductive medicine
    (第56回日本生体医工学会大会 2017)
  • TRPC3 participates in the angiotensin II type 1 receptor-dependent slow force response to stretch in mouse cardiomyocytes
    (7th International Workshop on Cardiac Mechano-Electric Coupling and Arrhythmia 2016)
  • TRPC3 participates in the angiotensin II type 1 receptor-dependent slow force response to stretch in mouse cardiomyocytes
    (The 45th European Muscle Conference 2016)
  • Localization of TRPC3 channels estimated by in-silico and cellular functional experiments
    (Experimental and Computational Biomedicine 2016)
  • Role of TRPC3 in a Slow Force Response to Stretch on Mice Cardiomyocytes
    (第8回アジア・オセアニア生理学会連合(FAOPS)2015年大会 2015)
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Education (1)：
  • - 2007 University of Oxford
Professional career (1)：
  • 博士(医学) (オックスフォード大学(英国))
Work history (5)：
  • 2019 - 現在 Asahikawa Medical University Dept. Physiology Professor
  • 2016 - 2019 - 岡山大学医歯薬学総合研究科 准教授
  • 2013 - 2016 岡山大学医歯薬学総合研究科 講師
  • 2013 - 2016 Senior Assistant Professor,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University
  • 2016 - - Associate Professor,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University
Committee career (3)：
  • 2015 - 日本生体医工学会 代議員
  • 2014 - 日本生理学会 評議員
  • 2009 - ヨーロッパ心臓病学会(European Society of Cardiology) フェロー(FESC)
Awards (1)：
  • 2005 - Sevier Poster Award
Association Membership(s) (4)：
日本生理学会 ,  ヨーロッパ心臓病学会(European Society of Cardiology) ,  米国生物物理学会(Biophysical Society) ,  日本生体医工学会
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