TSUJINO hirofumi

Research field (1)： Pharmaceuticals - analytical and physicochemistry

Research keywords (2)：シトクロムP450 , ヘムタンパク質

Research theme for competitive and other funds (6)：

2019 - 2023 Redox control of disease-related metalloproteins and its application to drug development
2018 - 2022 Interpretability of Machine Learning-Assisted Control Methods through Stochastic Controllability Analysis
2015 - 2018 Origination of antibiotic drugs for tuberculosis based on the structural analyses of novel target proteins
2014 - 2018 Control systems that utilize interaction with environmental fluctuation
2014 - 2017 For discovery of new drugs; elucidation of correlation between reaction mechanisms and structural features in Ngb/Cgb

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Papers (58)：

Yuki Wada, Kwangkyun Jang, Hirokazu Ishii, Yuki Watakabe, Motosuke Tsutsumi, Makoto Sako, Tsunayoshi Takehara, Takeyuki Suzuki, Hirofumi Tsujino, Yasuo Tsutsumi, et al. Absorption, Fluorescence, and Two-Photon Excitation Ability of 5-o-Tolyl-11 (or 13)-o-tolylisoindolo[2,1-a]quinolines Prepared by Ring-Closing Metathesis and [2+3] Cycloaddition. Chemistry, an Asian journal. 2024. e202401073
Sota Manabe, Yuya Haga, Hirofumi Tsujino, Yudai Ikuno, Haruyasu Asahara, Kazuma Higashisaka, Yasuo Tsutsumi. Treatment of polyethylene microplastics degraded by ultraviolet light irradiation causes lysosome-deregulated cell death. Scientific Reports. 2024. 14. 1
Yudai Ikuno, Hirofumi Tsujino, Yuya Haga, Sota Manabe, Wakaba Idehara, Mii Hokaku, Haruyasu Asahara, Kazuma Higashisaka, Yasuo Tsutsumi. Polyethylene, whose surface has been modified by UV irradiation, induces cytotoxicity: A comparison with microplastics found in beaches. Ecotoxicology and environmental safety. 2024. 277. 116346-116346
Kazuho Ban, Shiho Nozaki, Takaaki Aijima, Shuki Oyama, Hirofumi Tsujino, Yusuke Kanematsu, Shuji Akai, Yoshinari Sawama. Furanyl bis(indolyl)methane as a palladium ion-selective chromogenic agent. Organic & biomolecular chemistry. 2024. 22. 14. 2734-2738
Hiroto Konishi, Yuya Haga, Moe Okumura, Hirofumi Tsujino, Kazuma Higashisaka, Yasuo Tsutsumi. Coculture with macrophages alters ferroptosis susceptibility of triple-negative cancer cells. Cell Death Discovery. 2024. 10. 1. 108-108

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MISC (8)：

東阪和馬, 芳賀優弥, 辻野博文, 堤康央. 微粒子曝露と脆弱な世代への健康影響 : 胎盤毒性/動態解析を例に-Health effects of fine particle exposure on vulnerable generations. Bio clinica = バイオクリニカ. 2022. 37. 1. 61-65
北本夏子, 芳賀優弥, 辻井勇気, 辻野博文, 辻野博文, 東阪和馬, 東阪和馬, 堤康央, 堤康央. The effect of cellular senescence caused by benzopyrene on cancer progression. 日本薬学会年会要旨集(Web). 2022. 142nd
Ying Lin, Kazuma Higashisaka, Takuya Shintani, Ayaka Maki, Sachiyo Hanamuro, Yuya Haga, Shinichiro Maeda, Hirofumi Tsujino, Kazuya Nagano, Yasushi Fujio, et al. Progesterone receptor membrane component 1 leads to erlotinib resistance, initiating crosstalk of Wnt/β-catenin and NF-κB pathways, in lung adenocarcinoma cells. Scientific reports. 2020. 10. 1. 4748-4748
井阪亮, 東阪和馬, 石田菜南, 坂橋優治, 山口慎太郎, 北原剛, 藤尾慈, 神出計, 辻野博文, 長野一也, et al. 近位尿細管の上皮間葉転換においてインテグリンリガンドが果たす役割の解明. 日本薬学会年会要旨集. 2020. 140年会. 26F-pm11S
Hidehiko Suzuki, Azusa Takahashi, Kyohei Matsushita, Xiangru Li, Hirofumi Tsujino, Akihiro Watari, Masuo Kondoh, Hiroshi Aoyama, Tadayuki Uno, Kiyohito Yagi. Preparation of a broad-specific claudin binder by using Clostridium perfringens enterotoxin. FASEB JOURNAL. 2012. 26

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Education (3)：

Work history (7)：

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Association Membership(s) (1)：

日本薬学会

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