Research keywords (9)：
translational alteration and diseases
, RNA
, ribosome
, eIF5-mimic protein (5MP)
, translational profiling
, Molecular dynamics analyses of RNA complexes
, translation initiation factor
, translation initiation
, translation (protein synthesis)
Research theme for competitive and other funds (2)：
2023 - 2029 non-AUG translation: Understanding the mechanism of human disease etiology through "wobble" in start codon selection
2020 - 2023 新規癌遺伝子5MP1によるnon-AUG翻訳制御の生物学的役割に関する研究
Papers (65)：
Takeru Kameda, Daniel K. Saha, Sourav Ray, Yuichi Togashi, Katsura Asano. Protocol for calculating binding free energy of RNA:RNA interactions through molecular dynamics simulations using adaptive biasing force technique. STAR Protocols. 2024. 5. 3. 103223-103223
Charles Jourdan F. Reyes, Katsura Asano. Between Order and Chaos: Understanding the Mechanism and Pathology of RAN Translation. Biological and Pharmaceutical Bulletin. 2023. 46. 2. 139-146
Chingakham Ranjit Singh, Naoki Tani, Akira Nakamura, Katsura Asano. Mass spectrometry analysis of affinity-purified cytoplasmic translation initiation complexes from human and fly cells. STAR protocols. 2022. 3. 4. 101739-101739
Charles Jourdan Reyes, Katsura Asano, Peter K Todd, Christine Klein, Aleksandar Rakovic. Repeat-Associated Non-AUG Translation of AGAGGG Repeats that Cause X-Linked Dystonia-Parkinsonism. Movement disorders : official journal of the Movement Disorder Society. 2022. 37. 11. 2284-2289
Chingakham Ranjit Singh, Rahul Jaiswal, Carlos R Escalante, Katsura Asano. Label-free protocol to quantify protein affinity using isothermal titration calorimetry and bio-layer interferometry of a human eIF5-mimic protein. STAR protocols. 2022. 3. 3. 101615-101615
Takashi Nagata, Hisashi Yoshida, Satoru Unzai, Takeshi Urano, Katsura Asano, Eiji Obayashi. Interactions between eukaryotic initiation factors implicated during ribosomal scanning and start codon recognition. The 56th Annual Meeting of the NMR Society of Japan, Tokyo Metropolitan Univ., Hachioji, 2017.11.14-16. 2017
Chelsea Moore, Sarah Gillaspie, Ji Wan, Eric Aube, Abbey Anderson, Chingakham Singh, Michael Witcher, Ivan Topisirovic, Shu-Bing Qian, Katsura Asano. Role of eIF5-mimic protein 1 (5MP1) for translational control in cancer. CANCER RESEARCH. 2017. 77
Obayashi, E, Urano, T, Asano, K, Katahira, M, Nagata, T. Structural and biochemical studies on eIF1 with eIF3c and eIF5; rearrangement of subunit interaction for accurate recognition of AUC start codon. The 6th International Symposium of Advanced Energy Science~Towards the Realization of Zero-Emission Energy~. 2015
Encyclopedia of systems biology
Springer 2013 ISBN:9781441998620
Translational control in biology and medicine
Cold Spring Harbor Laboratory Press 2006 ISBN:0879697679
Education (2)：
1989 - 1994 The University of Tokyo Graduate School of Science
1984 - 1989 The University of Tokyo Faculty of Science Department of Biophysics and Biochemistry
Professional career (3)：
Ph. D. (The University of Tokyo)
Master of Science (The University of Tokyo)
Bachelor of Science (The University of Tokyo)
Work history (6)：
2020/04 - 現在 Hiroshima University
2014/07 - 現在 Kansas State University Division of Biology
2006/07 - 2014/06 Kansas State University, Manhattan, KS Division of Biology,
2001/01 - 2006/06 Kansas State University, Manhattan, KS Division of Biology
1996/04 - 2000/12 Laboratory of Eukaryotic Gene Regulation, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD
1994/04 - 1996/03 Department of Biological Chemistry, School of Medicine, University of California, Davis, CA
