Natsumeda Manabu

Affiliation and department：

Research field (1)： Neurosurgery

Research theme for competitive and other funds (14)：

2022 - 2026 Investigation of development mechanism and preemptive medicine for IDH-mutant glioma based on genomic analysis of normal brain tissues
2024 - 2026 悪性リンパ腫における細胞内脂質輸送制御破綻の検証
2022 - 2025 Development of novel therapies for rare malignant brain tumors by drug screening using proprietary tumor cell lines
2021 - 2025 Chemo-sensitization of brain tumors by manipulation of SLFN11
2021 - 2024 Visualization of microenvironments of malignant glioma utilizing 7T-MRI and 3D tissue clearing technology

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Papers (110)：

Shoji Saito, Yuka Nakamura, Satoshi Miyashita, Tokiharu Sato, Kana Hoshina, Masayasu Okada, Hitoshi Hasegawa, Makoto Oishi, Yukihiko Fujii, Jakob Körbelin, et al. CRISPR/CasRx suppresses KRAS-induced brain arteriovenous malformation developed in postnatal brain endothelial cells in mice. JCI Insight. 2024. 9. 22
Shoji Saito, Yuka Nakamura, Satoshi Miyashita, Tokiharu Sato, Kana Hoshina, Masayasu Okada, Hitoshi Hasegawa, Makoto Oishi, Yukihiko Fujii, Jakob Körbelin, et al. CRISPR/CasRx suppresses KRAS-induced brain arteriovenous malformation developed in postnatal brain endothelial cells in mice. JCI insight. 2024. 9. 22
Takahiro Watanabe, Shinichi Noto, Manabu Natsumeda, Shinji Kimura, Fumie Ikarashi, Satoshi Tabata, Mayuko Takano, Yoshihiro Tsukamoto, Makoto Oishi. Improvements in activities of daily living among patients with brain tumors are associated with age, baseline physical function, duration of rehabilitation, and tumor recurrence but not type. International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation. 2024
Toshiya Kizaki, Masato Kanazawa, Takanobu Ishiguro, Manabu Natsumeda, Mari Tada, Hiroshi Shimizu, Kouichirou Okamoto, Makoto Oishi, Akiyoshi Kakita, Yukihiko Fujii, et al. Indications for a brain biopsy in neurological diseases of unknown etiology: The role of magnetic resonance imaging findings and liquid biopsy in yielding definitive pathological diagnoses. Journal of the neurological sciences. 2024. 463. 123150-123150
Yuki Tanaka, Manabu Natsumeda, Masayuki Ohashi, Rie Saito, Nayuta Higa, Toshiaki Akahane, Hideki Hashidate, Junko Ito, Satoshi Fujii, Atsushi Sasaki, et al. Primary spinal cord gliomas: Pathologic features associated with prognosis. Journal of neuropathology and experimental neurology. 2024

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MISC (161)：

木崎利哉, 金澤雅人, 石黒敬信, 棗田学, 岡本浩一郎, 大石誠, 柿田明美, 藤井幸彦, 小野寺理. 非腫瘍性疾患における脳生検の適応決定に有用な画像所見. 日本神経学会学術大会プログラム・抄録集. 2024. 65th
棗田学, 温城太郎, 高橋陽彦, 渡邉潤, 塚本佳広, 大石誠, 柿田明美, 瀧澤淳, 正木康史, 林康彦. 脳腫瘍診断におけるliquid biopsyの可能性中枢神経再発を来すsystemic diffuse large B cell lymphomaは高率にMYD88変異を有する. Brain Tumor Pathology. 2023. 40. Suppl. 069-069
棗田学. PCNSLの診断および治療最新のトピックスを交えて. Brain Tumor Pathology. 2023. 40. Suppl. 082-082
高橋陽彦, 棗田学, 塚本佳広, 清水宏, 岡本浩一郎, 峰晴陽平, 荒川芳輝, 大石誠, 柿田明美, 藤井幸彦. FGFR3-TACC3 fusionを伴うIDH野生型神経膠腫はCTで石灰化を高率に有する. Brain Tumor Pathology. 2023. 40. Suppl. 099-099
伊師雪友, ツァン・ヨンザン, ツァン・アリ, 佐々木貴浩, 渡邊潤, 阿部幸喜, 棗田学, 山口秀, 藤村幹, 橋詰倫太郎. AT/RTのEZH2およびBRD4を標的とした新規治療. Brain Tumor Pathology. 2023. 40. Suppl. 109-109

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Education (2)：

2007 - 2011 新潟大学医歯学総合研究科(神経病理学)
1997 - 2003 Niigata University Faculty of Medicine School of Medicine

Work history (3)：

2023/04 - 現在 Niigata University Brain Research Institute Advanced Neurological Disease Research Branch Specially Appointed Associate Professor
2013/04 - 2023/03 Niigata University Brain Research Institute
2013/09 - 2016/03 Johns Hopkins大学神経病理学分野 Postdoctoral fellow

Committee career (9)：

2024/05 - 現在日本脳神経外科コングレス運営委員
2024/03 - 現在国際神経放射線生物学会理事
2022/07 - 現在日本脳神経外科国際学会フォーラム運営委員
2022/04 - 現在日本分子脳神経外科学会世話人
2021/04 - 現在日本脳腫瘍病理学会評議委員

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Awards (6)：

2024/08 - 令和6年新潟大学優秀論文表彰受賞
2024/06 - 第28回有壬記念研究奨励賞
2015/03 - Johns Hopkins大学病理学部門Young Investigator Day 若手研究奨励賞
2012/07 - 第27回日本脳神経外科国際学会フォーラム最優秀発表賞
2010/08 - 第40回新潟神経学夏期セミナー中田瑞穂若手研究奨励賞

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Association Membership(s) (9)：

アメリカ脳腫瘍学会 , 日本Awake Surgery学会 , THE JAPANESE SOCIETY FOR PEDIATRIC NEUROSURGERY , THE JAPAN SOCIETY FOR CNS COMPUTED IMAGING , 日本分子神経外科学会 , 日本脳腫瘍学会 , THE JAPAN SOCIETY OF BRAIN TUMOR PATHOLOGY , THE JAPANESE CONGRESS OF NEUROLOGICAL SURGEONS , THE JAPAN NEUROSURGICAL SOCIETY

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