Research theme for competitive and other funds (13):
2021 - 2027 皮膚ミトコンドリア老化・初期化の自然免疫系によるコントロール
2023 - 2026 Elucidation of atopic dermatitis pathology through nucleic acid-independent single-cell microbiome analysis
2023 - 2025 Analysis of the association between polyamine production in the scalp bacterial flora and hair growth.
2020 - 2023 Novel method of skin metatranscriptome analysis for predicting the onset of skin disease
2018 - 2021 The development and functional regulation of tissue macrophages by resident mast cells
2017 - 2020 Novel method for controlling "Evolutionary risk management strategy" during genome evolution of pathogenic bacterial by skin microbiota
2016 - 2019 Establishment of skin microbe-host immunity analysis method based on understanding the concept of "superorganism"
2016 - 2019 The quest for immune checkpoint inhibitor biomarker derived from tumor exsosomes
2016 - 2018 経表皮C.albicans感染におけるTh17の獲得免疫系での役割の解析
2014 - 2018 Application for a new less-invasive, personalized 3-demensional epidermal model: Search for new responsible genes related to Atopic Dermatitis
2015 - 2017 Virome analysis of psoriasis based on the community shuffling model
2014 - 2016 Gene-based analysis of NETs-associated DNA in autoantibody-mediated diseases
2014 - 2016 Development of novel therapeutic targets for atopic dermatitis by controlling quorum-sensing in Staphylococcus aureus
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Papers (55):
Miki Kume, Hanako Koguchi-Yoshioka, Shuichi Nakai, Yutaka Matsumura, Atsushi Tanemura, Kazunori Yokoi, Shoichi Matsuda, Yuumi Nakamura, Naoya Otani, Mifue Taminato, et al. Downregulation of Semaphorin 4A in keratinocytes reflects the features of non-lesional psoriasis. 2024
Junpei Yamaguchi, Teruhisa Manome, Yasumasa Hara, Yuriko Yamazaki, Yuumi Nakamura, Masami Ishibashi, Akiko Takaya. Physalin H, physalin B, and isophysalin B suppress the quorum-sensing function of Staphylococcus aureus by binding to AgrA. Frontiers in Pharmacology. 2024. 15
Yuriko Yamazaki, Tomoka Ito, Masakazu Tamai, Seitaro Nakagawa, YUUMI NAKAMURA. The role of Staphylococcus aureus quorum sensing in cutaneous and systemic infections. Inflammation and Regeneration. 2024
山口隼平, 馬目照久, 原康雅, 原康雅, 山崎由里子, 松岡悠美, 石橋正己, 石橋正己, 高屋明子, 高屋明子, et al. Physalin H inhibits expression of the agr quorum sensing system without suppressing Staphylococcus aureus growth. 日本薬学会年会要旨集(Web). 2023. 143rd
松岡悠美, 高橋弘喜, 高屋明子. Development of novel therapeutic approach for systemic persister infections. 千葉大学真菌医学研究センター報告. 2023. 26
日本細菌学会
, THE JAPANESE SOCIETY FOR IMMUNOLOGY
, JAPANESE SOCIETY OF ALLERGOLOGY
, THE JAPANESE SOCIETY FOR INVESTIGATIVE DERMATOLOGY
, THE JAPANESE DERMATOLOGICAL ASSOCIATION