Research keywords (4):
Neuroimmunology
, Tissue regeneration and fibrosis
, Mucosal immunology
, Inflammatory bowel disease
Research theme for competitive and other funds (8):
2024 - 2027 Elucidation of Neuro-Immune Interactions in Inflammatory Bowel Disease and Development of Novel Treatments Using New Neural Tracing Methods
2023 - 2026 Elucidation of the gut-liver-brain axis in response to host-invading bacteria and the development of treatments for gastrointestinal immune diseases
2021 - 2024 炎症性組織レジリエンスと組織障害エントロピーの統合的理解と炎症収束学の創成
2021 - 2024 Elucidation of the entropy of tissue damage in digestive organs and development of new therapeutic approaches
2020 - 2023 宿主侵入菌に対する腸管免疫応答を介した消化器免疫難病の病態解明
2020 - 2023 Gene regulation in the gut T cells and IBD
2019 - 2022 Circadian clock and proliferative metabolism in the intestinal T lymphocytes
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Papers (132):
Sakamoto K., Okabayashi K., Seishima R., Shigeta K., Kiyohara H., Mikami Y., Kanai T., Kitagawa Y. Radiomics prediction of surgery in ulcerative colitis refractory to medical treatment. Techniques in Coloproctology. 2025. 29. 1. 113
Shih, HY, Sciumè, G., Mikami, Y. Epigenomic control of immunity: from mechanisms to therapeutic targets in inflammatory bowel diseases. INTERNATIONAL IMMUNOLOGY. 2025
Shigehara A., Kiyohara H., Teratani T., Nakamoto N., Mikami Y., Kanai T. Gut Microbiota and Interorgan Communication among the Gut, Brain, and Beyond. Internal medicine (Tokyo, Japan). 2025
Matsuoka, K., Motoya, S., Yamamoto, T., Matsuura, M., Fujii, T., Shinzaki, S., Mikami, Y., Arai, S., Oshima, J., Endo, Y., et al. Post-marketing surveillance of tofacitinib in patients with ulcerative colitis in Japan: a final report of safety and effectiveness data. JOURNAL OF GASTROENTEROLOGY. 2025. 60. 8. 979-989
Yamane, T., Masaoka, T., Ishii, C., Masuoka, H., Suda, W., Kurokawa, S., Kishimoto, T., Mikami, Y., Fukuda, S., Kanai, T. Factors Contributing to the Efficacy of Fecal Microbiota Transplantation for Diarrhea-Dominant Functional Bowel Disorders. DIGESTION. 2025. 1-11
Matsuoka K., Yamazaki H., Nagahori M., Kobayashi T., Omori T., Mikami Y., Fujii T., Shinzaki S., Saruta M., Matsuura M., et al. Correction: Association of ulcerative colitis symptom severity and proctocolectomy with multidimensional patient-reported outcomes: a cross-sectional study(Journal of Gastroenterology, (2023), 58, (751-765), 10.1007/s00535-023-02005-7). Journal of Gastroenterology. 2024. 59. 7. 644-646
Niemi M.E.K., Karjalainen J., Liao R.G., Neale B.M., Daly M., Ganna A., Pathak G.A., Andrews S.J., Kanai M., Veerapen K., et al. Erratum to: Mapping the human genetic architecture of COVID-19 (Nature, (2021), 600, 7889, (472-477), 10.1038/s41586-021-03767-x). Nature. 2023. 621. 7977. E7-E26
Masahiro Kanai, Shea J. Andrews, Mattia Cordioli, Christine Stevens, Benjamin M. Neale, Mark Daly, Andrea Ganna, Gita A. Pathak, Akiko Iwasaki, Juha Karjalainen, et al. A second update on mapping the human genetic architecture of COVID-19. Nature. 2023. 621. 7977. E7-E26
Matsuoka K., Fujii T., Okamoto R., Yamada A., Kunisaki R., Matsuura M., Watanabe K., Shiga H., Takatsu N., Bamba S., et al. Correction: Characteristics of adult patients newly diagnosed with Crohn’s disease: interim analysis of the nation-wide inception cohort registry study of patients with Crohn’s disease in Japan (iCREST-CD) (Journal of Gastroenterology, (2022), 57, 11, (867-878), 10.1007/s00535-022-01907-2). Journal of Gastroenterology. 2023. 58. 6. 602-603
Ishige T., Shimizu T., Watanabe K., Arai K., Kamei K., Kudo T., Kunisaki R., Tokuhara D., Naganuma M., Mizuochi T., et al. Correction to: Expert consensus on vaccination in patients with inflammatory bowel disease in Japan (Journal of Gastroenterology, (2023), 58, 2, (135-157), 10.1007/s00535-022-01953-w). Journal of Gastroenterology. 2023. 58. 4. 431-432
RESIDENT NON-CLASSICAL MONOCYTES ARE CRITICALLY IMPORTANT FOR TISSUE DESTRUCTION IN ARTHRITIS
(ANNALS OF THE RHEUMATIC DISEASES 2017)
Education (1):
2008 - 2012 Keio University Graduate School of Medicine
Professional career (1):
PhD (Medicine) (Keio University)
Work history (8):
2023/05 - 現在 Keio University Hospital IBD Centre Vice-Director
2021/10 - 現在 Keio University School of Medicine Division of Gastroenterology and Hepatology, Department of Internal Medicine, Associate Professor
2021/04 - 2021/09 Keio University School of Medicine Division of Gastroenterology and Hepatology, Department of Internal Medicine, Assistant Professor
2020/10 - 2021/03 Keio University School of Medicine Division of Gastroenterology and Hepatology, Department of Internal Medicine, Assistant Professor
2020/04 - 2020/09 Keio University School of Medicine Division of Gastroenterology and Hepatology, Department of Internal Medicine, Assistant Professor
2018/04 - 2020/03 Keio University School of Medicine Division of Gastroenterology and Hepatology, Department of Internal Medicine, Project Assistant Professor
2013/09 - 2018/03 National Institutes of Health National Institute of Arthritis and Musculoskeletal and Skin Diseases Postdoctoral Fellow/Supplemental Visiting Fellow
2008/04 - 2018/03 Keio University School of Medicine Division of Gastroenterology and Hepatology, Department of Internal Medicine, Assistant Professor
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Awards (6):
2025/06 - Kitasato Award
2021/12 - 日本免疫学会研究奨励賞
2021/01 - 慶應医学賞 ライジング・スター賞
2018/12 - 第55回日本消化器免疫学会総会 奨励賞
2016/10 - NIH Group Merit Award
2011 - Keio University School of Medicine, Sanshikai 三四会奨励賞