Research field (2)：
Radiology
, Bioorganic chemistry
Research theme for competitive and other funds (11)：
2024 - 2027 Evaluation of a PET imaging ligand for microglia in Alzheimer's diseases
2023 - 2026 Synthesis of functional PET probes targeting enzymes specifically expressed in glioma
2023 - 2026 脳内に発現するTLR4を標的としたPETイメージング製剤の開発
2023 - 2025 Development of an in vivo cell tracking method using biological orthogonal reactions and PET
2021 - 2024 Development of PET imaging of brain immunity as a biomarker for drug development to treat neurodegenerative diseases
2021 - 2023 Development of brain PET imaging using bioorthogonal reactions
2019 - 2022 In vivo investigation of neuroinflammation of AD with PET molecular imaging
2019 - 2022 Development of DNA aptamer PET ligands targeting toll-like receptor 4
2018 - 2021 PET imaging of microglia, a novel drug target for neurodegenerative diseases
2018 - 2021 アルツハイマー病治療薬としての 非環式レチノイドのポテンシャル探索
2013 - 2016 Development of PET probes of neuroprotective molecular components in oriental medicines
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Papers (26)：
Hisaka Kurita, Naoki Hirasawa, Saori Yabe, Ayu Okuda, Takanori Murakami, Kazuki Ohuchi, Aya Ogata, Hiroki Yoshioka, Akiyoshi Kakita, Isao Hozumi, et al. MicroRNA-5572 Is Associated with Endoplasmic Reticulum Stress Responses in Low Zinc Treated and SOD1 G85R-Transfected HEK293 Cells. Biological & pharmaceutical bulletin. 2024. 47. 10. 1717-1725
Fumihiko Yasuno, Yasuyuki Kimura, Aya Ogata, Hiroshi Ikenuma, Junichiro Abe, Hiroyuki Minami, Takashi Nihashi, Kastunori Yokoi, Saori Hattori, Nobuyoshi Shimoda, et al. Trait-anxiety and glial-related neuroinflammation of the amygdala and its associated regions in Alzheimer's disease: A significant correlation. Brain, behavior, & immunity - health. 2024. 38. 100795-100795
Yosuke Tsukiboshi, Yurie Mikami, Hanane Horita, Aya Ogata, Azumi Noguchi, Satoshi Yokota, Kenichi Ogata, Hiroki Yoshioka. Protective effect of Sasa veitchii extract against all-trans-retinoic acid-induced inhibition of proliferation of cultured human palate cells. Nagoya Journal of Medical Science. 2024
Takayuki Sakai, Aya Ogata, Hiroshi Ikenuma, Takashi Yamada, Saori Hattori, Junichiro Abe, Shinichi Imamura, Masanori Ichise, Mari Tada, Akiyoshi Kakita, et al. A novel PET probe to selectively image heat shock protein 90α/β isoforms in the brain. EJNMMI radiopharmacy and chemistry. 2024. 9. 1. 19-19
Hiroki Yoshioka, Yosuke Tsukiboshi, Hanane Horita, Hisaka Kurita, Aya Ogata, Kenichi Ogata, Hyogo Horiguchi. Sasa veitchii extract alleviates phenobarbital-induced cell proliferation inhibition by upregulating transforming growth factor-beta 1. Traditional and Kampo Medicine. 2024
High brain permeability of 11C-labeled peretinoin, guiding to expose drug’s novel CNS activity
(13th World Federation of Nuclear Medicine and Biology 2022)
First-in-Human PET imaging of [11C]NCGG401 for colony-stimulating factor 1 receptor
(13th World Federation of Nuclear Medicine and Biology 2022)
2016/04 - 2017/03 Aichi Institute of Technology Faculty of Engineering, Department of Applied Chemistry
2016/01 - 2016/03 Gifu University Faculty of Engineering
2014/04 - 2015/12 Gifu University
2011/04 - 2014/03 豊田合成株式会社
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Committee career (1)：
2023/09 - 現在 日本生化学会中部支部 第3グループ幹事
Awards (5)：
2024/05 - (岐阜医療科学大学) 令和6年度研究奨励賞
2023/04 - (岐阜医療科学大学) 令和5年度研究奨励賞
2023/04 - 第31回日本医学会総会 6NCリトリートポスターセッション JH本部長賞
2022/08 - 第7回NCGG (国立長寿医療研究センター) サマーリサーチセミナー優秀賞
2009/11 - The Joint Symposium of 5th annual meeting Oligonucleotide Therapeutics society and the 19th Antisense Symposium Poster Award (Nucleic Acids Research Award, Antisense Award)
Association Membership(s) (5)：
AMERICAN CHEMICAL SOCIETY
, 日本核酸医薬学会
, THE CHEMICAL SOCIETY OF JAPAN
, 日本生化学会
, JAPANESE SOCIETY OF NUCLEAR MEDICINE
