Shinji Kohsaka

コウサカシンジ | Shinji Kohsaka

Affiliation and department：

Research field (1)： Genomics

Research theme for competitive and other funds (9)：

2022 - 2026 次世代トランスクリプトーム解析を用いた肺癌個別化医療開発
2021 - 2024 分子標的治療耐性化メカニズムの網羅的探索
2019 - 2024 Reprogramming of cancer stem cells by high-function hydrogels creates basis to establish novel cancer therapy
2019 - 2023 骨軟部腫瘍の「小胞体ストレス」機能解析に基づいた新規治療法開発
2019 - 2023 がんクリニカルシークエンス解析に基づいた「骨軟部腫瘍分子標的」の作用機序解明

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Papers (181)：

Kousuke Watanabe, Shinji Kohsaka, Kenji Tatsuno, Aya Shinozaki-Ushiku, Hideaki Isago, Hidenori Kage, Tetsuo Ushiku, Hiroyuki Aburatani, Hiroyuki Mano, Katsutoshi Oda. Analysis of quality metrics in comprehensive cancer genomic profiling using a dual DNA-RNA panel. Practical laboratory medicine. 2024. 39. e00368
Yukina Shirai, Toshihide Ueno, Shinya Kojima, Hiroshi Ikeuchi, Rina Kitada, Takafumi Koyama, Fumiyuki Takahashi, Kazuhisa Takahashi, Koichi Ichimura, Akihiko Yoshida, et al. The development of a custom RNA-sequencing panel for the identification of predictive and diagnostic biomarkers in glioma. Journal of neuro-oncology. 2024
Bunpei Miyazaki, Toshihide Ueno, Masanaka Sugiyama, Shinya Kojima, Ayumu Arakawa, Kayoko Tao, Kazuki Tanimura, Kouya Shiraishi, Shigehiro Yagishita, Shinji Kohsaka, et al. Promoter swapping of truncated PDGFRB drives Ph-like acute lymphoblastic leukemia. npj Precision Oncology. 2023. 7. 1
Nobuhiko Hasegawa, Takuo Hayashi, Hidetaka Niizuma, Kazutaka Kikuta, Jungo Imanishi, Makoto Endo, Hiroshi Ikeuchi, Keita Sasa, Kei Sano, Kaoru Hirabayashi, et al. Detection of Novel Tyrosine Kinase Fusion Genes as Potential Therapeutic Targets in Bone and Soft Tissue Sarcomas Using DNA/RNA-based Clinical Sequencing. Clinical orthopaedics and related research. 2023
Takeshi Hirose, Masachika Ikegami, Shinya Kojima, Akihiko Yoshida, Makoto Endo, Eijiro Shimada, Masaya Kanahori, Ryunosuke Oyama, Yoshihiro Matsumoto, Yasuharu Nakashima, et al. Extensive analysis of 59 sarcoma-related fusion genes identified pazopanib as a potential inhibitor to COL1A1-PDGFB fusion gene. Cancer science. 2023. 114. 10. 4089-4100

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MISC (41)：

Kazuya Takamochi, Kieko Hara, Takuo Hayahshi, Shinji Kohsaka, Fumiyuki Takahashi, Yoshiyuki Suehara, Kenji Suzuki. The clinical significance of PD-L2 expression in lung adenocarcinoma. CANCER SCIENCE. 2022. 113. 1011-1011
長谷川延彦, 高阪真路, 窪田大介, 末原義之, 高木辰哉, 石島旨章. Liquid biopsy in soft tissue and bone tumors. 別冊整形外科. 2021. 79
Taisei Kurihara, Yoshiyuki Suehara, Keisuke Akaike, Takuo Hayashi, Shinji Kohsaka, Nobuhiko Hasegawa, Tatsuya Takagi, Taketo Okubo, Youngji Kim, Takashi Yao, et al. Detection of Fusion Genes in Inflammatory Myofibroblastic Tumor/Inflammatory Pseudotumor by Nanostring-Based Screening System. LABORATORY INVESTIGATION. 2020. 100. SUPPL 1. 59-60
Taisei Kurihara, Yoshiyuki Suehara, Keisuke Akaike, Takuo Hayashi, Shinji Kohsaka, Nobuhiko Hasegawa, Tatsuya Takagi, Taketo Okubo, Youngji Kim, Takashi Yao, et al. Detection of Fusion Genes in Inflammatory Myofibroblastic Tumor/Inflammatory Pseudotumor by Nanostring-Based Screening System. MODERN PATHOLOGY. 2020. 33. SUPPL 2. 59-60
末原義之, 高阪真路, 林大久生, 佐々恵太, 栗原大聖, 佐野圭, 赤池慶祐, 金子和夫, 齋藤剛, 間野博行, et al. 軟部肉腫pazopanib著効因子12q13-14遺伝子変化に対する検証コホート. 日本整形外科学会雑誌. 2020. 94. 2

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Lectures and oral presentations (43)：

がんゲノム医療におけるリキッドバイオプシーの有用性と現状
(第62回日本臨床細胞学会総会春期大会 2021)
発がん関連遺伝子における生殖細胞系列バリアントのハイスループット機能解析法
(遺伝性腫瘍セミナー 2021)
Liquid型パネルとC-CATリポジトリの活用
(第18回日本臨床腫瘍学会学術集会 2021)
がん個別化医療の実現に向けた戦略的研究開発
(シンポジウム, AI技術が切り拓く新たなリウマチ学に向けた教育シンポジウム 2021)
がんゲノム医療の現況と展望
(第33回横浜市立大学がんプロ合同セミナー 2020)

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Awards (4)：

2019 - Incitement Award of the Japanese Association of Medical Science
2019 - The Young Scientists’ Prize of the Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology
2018 - Incitement Award of the Japanese Cancer Association
2014 - Incitement Award of the Japanese Association for Molecular Target Therapy of Cancer

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