Research field (2):
Structural biochemistry
, Biophysics
Research keywords (8):
生物物理学
, Wood Biomass
, Protein
, Virus
, Enzyme
, Molecular Biology
, Structural Biology
, Nucleic Magnetic Resonance
Research theme for competitive and other funds (3):
2022 - 2025 Development of cancer selective infectious virus vector that slows tumor growth
2019 - 2020 HIVのVifによる異なる2種類の「ヒト防御システム無力化手段」の同時阻害
2017 - 2020 Inactivation mechanism of HIV Vif protein using host cellular proteins against human anti-viral factor
Papers (7):
Kazuyuki Kumagai, Keisuke Kamba, Takuya Suzuki, Yuto Sekikawa, Chisato Yuki, Michiaki Hamada, Kayoko Nagata, Akifumi Takaori-Kondo, Li Wan, Masato Katahira, et al. Selection and characterization of aptamers targeting the Vif-CBFβ-ELOB-ELOC-CUL5 complex. Journal of biochemistry. 2024
Keisuke Kamba, Li Wan, Satoru Unzai, Ryo Morishita, Akifumi Takaori-Kondo, Takashi Nagata, Masato Katahira. Direct inhibition of human APOBEC3 deaminases by HIV-1 Vif independent of the proteolysis pathway. Biophysical Journal. 2023
Afaf Eladl*, Yudai Yamaoki*, Keisuke Kamba*, Shoko Hoshina, Haruka Horinouchi, Keiko Kondo, Shou Waga, Takashi Nagata, Masato Katahira (*: equally contributed). NMR characterization of the structure of the intrinsically disordered region of human origin recognition complex subunit 1, hORC1, and of its interaction with G-quadruplex DNAs. Biochemical and Biophysical Research Communications. 2023
Li Wan, Keisuke Kamba, Takashi Nagata, Masato Katahira. An insight into the dependence of the deamination rate of human APOBEC3F on the length of single-stranded DNA, which is affected by the concentrations of APOBEC3F and single-stranded DNA. Biochimica et Biophysica Acta (BBA) - General Subjects. 2020. 1864. 2. 129346-129346
Shou Waga, Yudai Yamaoki, Afaf Eladl, Keisuke Kamba, Shoko Hoshina, Haruka Horinouchi, Keiko Kondo, Takashi Nagata, Masato Katahira. NMR analysis on the binding sites of human origin recognition complex subunit 1 to G-quadruplex structure of DNA. The 14th International Symposium of Advanced Energy Science. 2023
Keisuke Kamba, Li Wan, Satoru Unzai, Ryo Morishita, Akifumi Takaori-Kondo, Takashi Nagata, Masato Katahira. HIV-1 Vif directly inhibit against human APOBEC3G deaminases independent of the ubiquitin-proteasome pathway. 23th ISMAR Conference. 2023
Keisuke Kamba, Li Wan, Satoru Unzai, Ryo Morishita, Akifumi Takaori-Kondo, Takashi Nagata, Masato Katahira. Additive effect of the interactions between the components of HIV-1-Vif: E3 ubiquitin ligase and human APOBEC3G may elevate the antiviral activity of APOBEC3G. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
2018/04 - 現在 Ritsumeikan University Pharmacy Part-time Lecturer
2016/06 - 現在 Kyoto University Institute of Advanced Energy Postdoctoral fellow
Awards (6):
2017 - 京都大学 平成28年度 京都大学 研究連携基盤 次世代研究者支援(後期)
2016/08 - The XXVIIth International Conference on Magnetic Resonance in Biological Systems Young InvestigatorAward Deamination mechanism coupled with sliding along single-stranded DNA of anti-HIV factor APOBEC3G as investigated by real-time NMR spectroscopy
THE SPECTROSCOPICAL SOCIETY OF JAPAN
, THE JAPANESE BIOCHEMICAL SOCIETY
, PROTEIN SCIENCE SOCIETY OF JAPAN
, THE NUCLEAR MAGNETIC RESONANCE SOCIETY OF JAPAN
, THE BIOPHYSICAL SOCIETY OF JAPAN
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN