Rchr
J-GLOBAL ID:201801010967301039   Update date: Sep. 04, 2021

Watanabe Hirotaka

Watanabe Hirotaka
Affiliation and department:
Job title: 特任講師
Research field  (1): Neuroscience - general
Research keywords  (6): Synapse ,  iPSC ,  Genome editing ,  Animal model ,  Neurobiology ,  Alzheimer's disease
Research theme for competitive and other funds  (2):
  • 2017 - 2020 プレシナプスにおけるアルツハイマー病発症の分子機序解析
  • 2015 - 2017 Development of neuron-specific analytical method to elucidate the mechanism underlying AD pathogenesis
Papers (37):
  • Jongkyun Kang, Hirotaka Watanabe, Jie Shen. Protocols for assessing neurodegenerative phenotypes in Alzheimer's mouse models. STAR protocols. 2021. 2. 3. 100654-100654
  • Hirotaka Watanabe, Rei Murakami, Hideyuki Okano. Amyloid β (Aβ) ELISA of Human iPSC-Derived Neuronal Cultures. Methods in molecular biology (Clifton, N.J.). 2021
  • Sho Yoshimatsu, Mayutaka Nakajima, Aozora Iguchi, Tsukasa Sanosaka, Tsukika Sato, Mari Nakamura, Ryusuke Nakajima, Eri Arai, Mitsuru Ishikawa, Kent Imaizumi, et al. Non-viral Induction of Transgene-free iPSCs from Somatic Fibroblasts of Multiple Mammalian Species. Stem cell reports. 2021. 16. 4. 754-770
  • Tsukika Sato, Kent Imaizumi, Hirotaka Watanabe, Mitsuru Ishikawa, Hideyuki Okano. Generation of region-specific and high-purity neurons from human feeder-free iPSCs. Neuroscience letters. 2021. 746. 135676-135676
  • Hirotaka Watanabe, Kent Imaizumi, Tetsuo Cai, Zhi Zhou, Taisuke Tomita, Hideyuki Okano. Flexible and accurate substrate processing with distinct presenilin/γ-secretases in human cortical neurons. eNeuro. 2021
more...
MISC (3):
Lectures and oral presentations  (7):
  • Development of novel stem cell tool to examine physiological functions of presenilin/γ-secretase in human neurons
    (NEURO2019 2019)
  • Presenilin and Alzheimer’s.
    (Blue Ribbon Panel Meeting 2018)
  • The roles of γ-secretase and its substrates on the pathogenesis of neurodegenerative dementia.
    (National Institute of Genetics- the 1801st Biological Symposium 2015)
  • Generation and analysis of mouse models to examine the roles of γ-secretase and its substrates on the pathogenesis of neurodegenerative dementia.
    (The 35th Annual Meeting of the Japan Neuroscience Society 2013)
  • Generation and analysis of mouse models to examine the roles of γ-secretase and its substrates on the pathogenesis of neurodegenerative dementia.
    (The Gordon Research Conference: Neurobiology of Brain Disorders 2012)
more...
Professional career (1):
  • 医学博士 (東京大学)
Work history (4):
  • 2015/05 - 現在 Keio University School of Medicine Department of Physiology Project Assistant Professor
  • 2006/11 - 2015/04 Brigham and Women's Hospital Department of Neurology Instructor
  • 2002/04 - 2006/10 The University of Tokyo The Institute of Medical Science Division of Host-Parasite Interaction
  • 1996/04 - 2002/03 JAPAN TOBACCO INC. Pharmaceutical Frontier Institute
Association Membership(s) (3):
Japan Society for Dementia Research ,  Society for Neuroscience ,  Japan Neuroscience Society
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page