Uruno Akira

ウルノアキラ | Uruno Akira

Affiliation and department：
Homepage URL (1)： http://www.dmbc.med.tohoku.ac.jp/official/index.html

Research field (5)： Basic brain sciences , Metabolism and endocrinology , Medical biochemistry , Nutrition and health science , Pathobiochemistry

Research keywords (5)： Alzheimer's disease , Nrf2 , Oxidative stress , Diabetes mellitus , Metabolism

Research theme for competitive and other funds (19)：

2020 - 2023 Glutathione regulations in Alzheimer's disease
2017 - 2020 Basic Research for Development of Chemical Surgery
2017 - 2020 Role of Nrf2 in Alzheimer's disease with diabetes mellitus
2017 - 2020 酸化ストレス増加が引き起こすインスリン抵抗性の病態解明とNrf2の役割(国際共同研究強化)
2017 - 2020 Nrf2を標的にした糖尿病に合併する認知症発症予防法の開発

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Papers (203)：

Ken Nagino, Yasutsugu Akasaki, Nobuo Fuse, Soichi Ogishima, Atsushi Shimizu, Akira Uruno, Yoichi Sutoh, Yayoi Otsuka-Yamasaki, Fuji Nagami, Jun Seita, et al. Integration of Digital Phenotyping and Genomics for Dry Eye Disease: Protocol for a Prospective Cohort Study. JMIR Research Protocols. 2025
Mami Ishikuro, Nobuo Fuse, Taku Obara, Aoi Noda, Genki Shinoda, Masatsugu Orui, Akira Uruno, Sayaka Yoshida, Naoko Takada, Shunsuke Fujioka, et al. Parental axial lengths and prenatal conditions related to child axial length: The TMM BirThree Cohort Study. AJO International. 2025. 2. 1
Sayuri Tokioka, Naoki Nakaya, Rieko Hatanaka, Kumi Nakaya, Mana Kogure, Ippei Chiba, Masato Takase, Kotaro Nochioka, Kai Susukita, Hirohito Metoki, et al. Association Between Sodium- and Potassium-Related Urinary Markers and the Prevalence of Atrial Fibrillation. Circulation journal : official journal of the Japanese Circulation Society. 2025
Masato Takase, Naoki Nakaya, Kozo Tanno, Mana Kogure, Rieko Hatanaka, Kumi Nakaya, Ippei Chiba, Sayuri Tokioka, Kotaro Nochioka, Takahiro Tabuchi, et al. Has the impact of cigarette smoking on mortality been underestimated by overlooking second-hand smoke? Tohoku medical megabank community-based cohort study. BMJ public health. 2025. 3. 1. e001746
Ken Nagino, Yasutsugu Akasaki, Nobuo Fuse, Soichi Ogishima, Atsushi Shimizu, Akira Uruno, Yoichi Sutoh, Yayoi Otsuka-Yamasaki, Fuji Nagami, Jun Seita, et al. Integration of Digital Phenotyping and Genomics for Dry Eye Disease: Protocol for a Prospective Cohort Study (Preprint). 2024

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MISC (73)：

石黒真美, 小原拓, 野田あおい, 篠田元気, 大類真嗣, 宇留野晃, 吉田清香, 高田菜生子, 藤岡俊亮, 西村尭幸, et al. 父母と小児の眼科的検査値の関連:三世代コホート調査. 日本疫学会学術総会講演集(Web). 2024. 34th
中谷直樹, 小暮真奈, 畑中里衣子, 中谷久美, 千葉一平, 菅野郁美, 小原拓, 中村智洋, 宇留野晃, 布施昇男, et al. 東北メディカル・メガバンク計画・地域住民コホート調査詳細三次調査(宮城)の進捗. 東北公衆衛生学会誌. 2022. 71. 28-28
小池海斗, 三枝大輔, 三枝大輔, 宇留野晃, 宇留野晃, 鈴木隆史, 鈴木隆史, 福内友子, 山岡法子, 芝大, et al. Lipidomic variations by the oxidative stress in the space flight. 質量分析総合討論会講演要旨集. 2022. 70th
小池海斗, 三枝大輔, 三枝大輔, 宇留野晃, 宇留野晃, 鈴木隆史, 鈴木隆史, 福内友子, 山岡法子, 芝大, et al. Lipidomic Variations by the Oxidative Stress in the Space Flight. Journal of the Mass Spectrometry Society of Japan. 2022. 70. 4
Furukawa Yoshihiro, Saigusa Daisuke, Kano Kuniyuki, Uruno Akira, Saito Ritsumi, Ito Motoo, Matsumoto Megumi, Aoki Jyunken, Yamamoto Masayuki, Nakamura Tomoki. High-resolution imaging mass spectrometry of CHN compounds in meteorites: organic synthesis in the early solar system. Abstracts of Annual Meeting of the Geochemical Society of Japan. 2022. 69. 190

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Books (3)：

Molecular Nutrition and Diabetes, 1st Edition.
Elsevier Science B.V. 2015
クッシング症候群診療マニュアル
診断と治療社 2009
Control and Diseases of Sodium Dependent Transporter Proteins and Ion Channels.
Elsevier Science B.V. 2000

Lectures and oral presentations (7)：

Nrf2を標的としたアルツハイマー病の治療戦略
(第4回医薬品開発研究センターシンポジウム「脳と創薬」 2021)
The multiple functions of Nrf2 in diabetes mellitus and obesity
(The Environmental Response V 2019)
The Keap1-Nrf2 system and oxidative damage in diabetes mellitus
(第61回日本糖尿病学会年次学術集会 2018)
Nrf2による代謝恒常性維持機構の解明
(第396回東北医学会例会)
糖尿病におけるKeap1-Nrf2系の役割
(第89回日本生化学会大会)

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Education (2)：

1998 - 2004 Tohoku University Graduate School of Medicine
1992 - 1998 Tohoku University School of Medicine

Professional career (1)：

博士(医学) (東北大学)

Work history (7)：

2017/10 - 現在東北大学大学院東北メディカルメガバンク機構准教授
2016/10 - 2017/09 東北大学大学院東北メディカルメガバンク機構講師
2012/04 - 2016/09 Tohoku University Graduate School of Medicine
2010/04 - 2012/03 Tohoku University Graduate School of Medicine
2007/04 - 2010/03 Tohoku University Graduate School of Medicine

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Awards (9)：

2018 - 平成29年度宮城県医師会医学奨励賞
2018 - 平成29年度坂田賞
2018 - 東北大学医学部奨学賞金賞
2017 - 日本生化学会東北支部奨励賞
2011 - 匂坂記念賞

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Association Membership(s) (5)：

THE JAPAN SOCIETY OF HUMAN GENETICS , 日本内科学会 , 日本内分泌学会 , 日本分子生物学会 , 日本生化学会

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