Research field (4)：
Immunology
, Oral medicine (pathology)
, Conservative dentistry and endodontics
, Allergies and connective tissue disease
Research theme for competitive and other funds (15)：
2025 - 2028 Spatiotemporal Analysis of the Proliferation and Differentiation Mechanisms of Gli1-Positive Stem Cells in the Periodontal Ligament During Orthodontic Tooth Movement
2018 - 2021 Dynamics of immune regulation in oral chronic inflammation and cancer, and their connection to systemic immunity
2017 - 2020 Role of VISTA in periodontitis
2014 - 2017 Analysis of characteristic immune regulation in the oral cavity
2014 - 2017 Roles of interleukin-33 in gingival Inflammation
2014 - 2017 Does Advanced Glycation End products (AGEs) is useful for risk management of implant treatment ?
2013 - 2016 Analyses for persistent inflammation in the skin and oral mucosa
2012 - 2014 Roles of interleukin-33 in gingival inflammation
2011 - 2014 Regulatory mechanisms in oral tissue-specific immune responses and tolerance
2010 - 2012 Involvement of Oral Mucosal Immune System in Sublingual Immunotherapy
2010 - 2011 T細胞に依存しない新たな補助シグナル分子機能の解明
2010 - 2011 The analysis of IL-33 inducible Th17 cells in allergic airway inflammation
2006 - 2007 チロシンキナーゼTxkによるマスト細胞のTh1/Th2応答の制御機構
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Papers (57)：
Kei Yamamoto, Yoshihiko Akashi, Kei Nakajima, Katsutoshi Kokubun, Tatsukuni Ohno, Kenichi Matsuzaka. Comparison of lymphocytic response to oral epithelial pre-neoplastic and inflammatory lesions. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY. 2026. 38. 2. 302-311
Nobuyuki Matsuura, Yuka Sendai, Minami Hasegawa, Mio Fukada, Natsuko Aida, Shoko Onodera, Kyotaro Koshika, Tatsukuni Ohno. Remimazolam Attenuates Lipopolysaccharide-Induced Inflammatory Responses in Macrophages. The Bulletin of Tokyo Dental College. 2026
Nobutaka Matsuura, Kazuyoshi Takeda, Yuka Sendai, Tatsuya Ichinohe, Nobuyuki Matsuura, Toshifumi Azuma, Ko Okumura, Tatsukuni Ohno. The translocator protein ligand Ro5-4864 inhibits RANKL-induced osteoclastogenesis in mice. Biomedical research (Tokyo, Japan). 2025. 46. 4. 167-176
Yuka Sendai, Kazuyoshi Takeda, Keisuke Ohta, Susumu Nakae, Kyotaro Koshika, Kei Kitamura, Makoto Higuchi, Tatsuya Ichinohe, Toshifumi Azuma, Ko Okumura, et al. Ro5-4864, a translocator protein ligand, regulates T cell-mediated inflammatory responses in skin. International Immunology. 2025. 37. 4. 221-234
Takafumi Numata, Masashi Ikutani, Ken Arae, Tatsukuni Ohno, Koki Okada, Takayuki Yoshimoto, Katsuko Sudo, Hajime Suto, Ko Okumura, Hirohisa Saito, et al. IL-10 promotes Th17 cell differentiation by enhancing STAT1-dependent IL-6 production via IgE-stimulated mast cells. Scientific reports. 2024. 14. 1. 26706-26706
石井武展, 薄場はるか, 大野建州, 溝口利英, 西井康. Neovascular network in the traction lateral periodontal ligament during tooth movement. 日本矯正歯科学会大会プログラム・抄録集. 2024. 83rd
薄場はるか, 石井武展, 大野建州, 溝口利英, 西井康. Cell surface receptors of Gli1-positive stem cells distributed around the periapical root of the tooth. 日本矯正歯科学会大会プログラム・抄録集. 2024. 83rd
