Rchr
J-GLOBAL ID:201801011260681630   Update date: Mar. 18, 2024

Yoshida Kazuki

Yoshida Kazuki
Affiliation and department:
Research field  (1): Pharmacology
Research keywords  (3): mast cell ,  extracellular ATP ,  P2 receptor
Research theme for competitive and other funds  (4):
  • 2022 - 2025 炎症性腸疾患におけるP2X4受容体の機能解析
  • 2019 - 2022 Establishment of therapeutic basis for allergic diseases targeting P2X4 receptor of mast cells
  • 2018 - 2022 イオンチャネル型受容体によるnRTKsの活性化調節機構の解明
  • 2018 - 2019 アレルギー性疾患におけるマスト細胞を中心としたP2X4受容体の機能解析
Papers (15):
  • Kazuki Yoshida, Masa-aki Ito, Isao Matsuoka. Enhancement of mast cells activation by ATP via P2X4 receptor. Journal of Pharmacological Sciences. 2024. 159. 1. 39-43
  • Norikazu Okuma, Masa-aki Ito, Tomoyoshi Shimizu, Atsuya Hasegawa, Shin’ya Ohmori, Kazuki Yoshida, Isao Matsuoka. Amplification of poly(I:C)-induced interleukin-6 production in human bronchial epithelial cells by priming with interferon-γ. Scientific Reports. 2023. 13. 1
  • Noriyuki Yamagiwa, Mika Komine, Fumi Hanaoka, Tomoya Nobuta, Kazuki Yoshida, Masaaki Ito, Isao Matsuoka. Exploratory study of oxatomide derivatives with high P2X7 receptor inhibitory activity. Bioorganic & Medicinal Chemistry Letters. 2022. 77. 129035-129035
  • Kazuki Yoshida, Shota Tanihara, Yuki Miyashita, Kosuke Obayashi, Masa-aki Ito, Kimiko Yamamoto, Toshiyashu Imai, Isao Matsuoka. P2X4 receptor stimulation enhances MrgprB2-mediated mast cell activation and pseudoallergic reactions in mice. Scientific Reports. 2022. 12. 1. 18613
  • Isao Matsuoka, Kazuki Yoshida, Masa-Aki Ito. Purinergic regulation of mast cell function: P2X4 receptor-mediated enhancement of allergic responses. Journal of pharmacological sciences. 2022. 150. 2. 94-99
more...
MISC (15):
  • 吉田一貴, 谷原祥太, 宮下友希, 大林晃右, 伊藤政明, 松岡功. P2X4 receptor signaling enhanced psuedallergyc response. 日本薬学会年会要旨集(Web). 2022. 142nd
  • 青木楓佳, 伊藤政明, 吉田一貴, 松岡功. Analysis of ATP-induced enhancement of interleukin 6 production in human glioblastoma. 日本薬学会年会要旨集(Web). 2022. 142nd
  • 秋吉玲未乃, 伊藤政明, 吉田一貴, 松岡功. Evaluation of mesenteric artery function in LPS-induced sepsis model mice. 日本薬学会年会要旨集(Web). 2022. 142nd
  • 大林昂右, 吉田一貴, 伊藤政明, 松岡功. Analysis of synergistic cytokine production induced by co-stimulation of ATP and PGE2 in mast cells. 日本薬学会年会要旨集(Web). 2022. 142nd
  • 大熊範和, 大熊範和, 伊藤政明, 吉田一貴, 松岡功. Synergistic effects of IFN-γ and poly(I:C) on cytokine production in human airway epithelial NCl-H292 cells. 日本薬学会年会要旨集(Web). 2022. 142nd
more...
Lectures and oral presentations  (21):
  • P2X4 receptor signaling enhance pseudallergic responses in mice
    (2022)
  • P2X4 receptor signaling potentiate Mas-relate G protein-coupled receptor B2-induced mast cell degranulation
    (2022)
  • P2X4受容体が結合組織型マスト細胞の脱顆粒反応に及ぼす影響
    (日本薬学会第141年会 2021)
  • プリン受容体を介するマスト細胞活性化メカニズムの解明
    (第64回日本薬学会関東支部大会 2020)
  • Effect of compound48/80 on antigen-dependent degranulation in BMMC
    (2020)
more...
Education (2):
  • 2013 - 2017 Takasaki University of Health and Welfare Graduate School Pharmacy Department of Pharmacy / Doctor degree
  • 2007 - 2013 Takasaki University of Health and Welfare Faculty of Pharmacy
Professional career (1):
  • 博士 ((薬学))
Work history (3):
  • 2023/04 - 現在 Takasaki University of Health and Welfare Faculty of Pharmacy
  • 2019/04 - 2023/03 Takasaki University of Health and Welfare Faculty of Pharmacy
  • 2017/04 - 2019/03 Takasaki University of Health and Welfare Faculty of Pharmacy
Awards (4):
  • 2022/03 - 日本薬学会 長井記念若手薬学研究者賞
  • 2022/03 - 日本薬理学会 年会優秀発表賞 P2X4受容体シグナルはMrgprB2を介したマスト細胞の活性化を増強する
  • 2020/09 - 日本薬学会関東支部 日本薬学会関東支部奨励賞 プリン受容体を介するマスト細胞活性化メカニズムの解明
  • 2017/03 - 日本薬学会 優秀発表賞 P2X7 受容体阻害薬 の担癌モデルマウス に対する効果
Association Membership(s) (3):
THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE JAPANESE PHARMACOLOGICAL SOCIETY
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