Rchr
J-GLOBAL ID:201801011262824837   Update date: Feb. 01, 2024

Noriko Motoi

Noriko Motoi
Affiliation and department:
Job title: Deputy Director
Other affiliations (2):
  • National Cancer Center  Research Institute   Visiting Researcher
  • Saitama Medical University  Saitama Medical Center Pathology   Visiting Associate Professor
Research field  (1): Human pathology
Research keywords  (6): 人体病理学 ,  Morphology ,  Cancer genomics ,  Digital Pathology ,  Neuroendocrine tumor ,  Lung Cance
Research theme for competitive and other funds  (18):
  • 2021 - 2024 Development study on pathological predictive biomarkers for cancer treatment
  • 2018 - 2021 Study on pathological indicator to predict response of cancer immune therapy
  • 2018 - 2020 18980565: 未来のがん診療に資する革新的技術を導入したバイオマーカー測定の有用性を評価する大規模前向き観察研究
  • 2018 - 2020 18K07036: がん免疫療法効果予測に資する病理学的指標の探索
  • 2017 - 2019 17824685: 高悪性度神経内分泌肺癌切除例に対する術後補助化学療法の標準治療確立のための研究研究
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Papers (268):
  • Yasuhiko Haga, Yoshitaka Sakamoto, Keiko Kajiya, Hitomi Kawai, Miho Oka, Noriko Motoi, Masayuki Shirasawa, Masaya Yotsukura, Shun-Ichi Watanabe, Miyuki Arai, et al. Whole-genome sequencing reveals the molecular implications of the stepwise progression of lung adenocarcinoma. Nature communications. 2023. 14. 1. 8375-8375
  • Tomohiro Tanaka, Yasushi Goto, Masafumi Horie, Ken Masuda, Yuki Shinno, Yuji Matsumoto, Yusuke Okuma, Tatsuya Yoshida, Hidehito Horinouchi, Noriko Motoi, et al. Whole Exome Sequencing of Thymoma Patients Exhibiting Exceptional Responses to Pemetrexed Monotherapy. Cancers. 2023. 15. 16
  • Kazunori Aoki, Yukari Nishito, Noriko Motoi, Yasuhito Arai, Nobuyoshi Hiraoka, Tatsuhiro Shibata, Yukiko Sonobe, Yoko Kayukawa, Eri Hashimoto, Mina Takahashi, et al. Tumor-infiltrating Leukocyte Profiling Defines Three Immune Subtypes of NSCLC with Distinct Signaling Pathways and Genetic Alterations. Cancer research communications. 2023. 3. 6. 1026-1040
  • Hitomi Jo, Tatsuya Yoshida, Shigehiro Yagishita, Mayu Ohuchi, Yuji Matsumoto, Yuki Shinno, Yusuke Okuma, Yasushi Goto, Hidehito Horinouchi, Noboru Yamamoto, et al. Clinical Characteristics and Pharmacokinetics Change of Long-Term Responders to Antiprogrammed Cell Death Protein 1 Inhibitor Among Patients With Advanced NSCLC. JTO clinical and research reports. 2023. 4. 4. 100474-100474
  • Eiichi Morii, Yutaka Hatanaka, Noriko Motoi, Akihiko Kawahara, Shinji Hamakawa, Takeshi Kuwata, Tadasuke Nagatomo, Yoshinao Oda, Aikou Okamoto, Ryota Tanaka, et al. Guidelines for Handling of Cytological Specimens in Cancer Genomic Medicine. Pathobiology : journal of immunopathology, molecular and cellular biology. 2023. 1-23
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MISC (742):
  • 野呂林太郎, 本田一文, 本田一文, 長島健悟, 元井紀子, 功刀しのぶ, 松林純, 武内進, 白石英晶, 岡野哲也, et al. Establishment of biomarker for detecting the potential metastasis, and the effect of adjuvant chemotherapy in lung adenocarcinomas with stage I. 日本呼吸器学会誌(Web). 2021. 10
  • 市川 晶博, 藤田 雄, 保坂 悠介, 門田 宰, 川本 浩徳, 渡邉 直昭, 伊藤 晶彦, 橋本 典生, 皆川 俊介, 原 弘道, et al. 非小細胞肺癌におけるシャペロン介在性オートファジー(CMA)を介した化学療法耐性機序の検討. 日本呼吸器学会誌. 2020. 9. 増刊. 177-177
  • Akihiko Miyanaga, Mari Masuda, Noriko Motoi, Koji Tsuta, Yuka Nakamura, Nobuhiko Nishijima, Shunichi Watanabe, Hisao Asamura, Akihiko Tsuchida, Masahiro Seike, et al. Whole-exome and RNA sequencing reveals chromosomal rearrangements associated with the recurrence of pulmonary carcinoid. CANCER RESEARCH. 2020. 80. 16
  • 水野孝昭, 吉田達哉, 元井紀子, 松元祐司, 新野祐樹, 角南久仁子, 小山隆文, 大熊裕介, 後藤悌, 堀之内秀仁, et al. 胸部悪性腫瘍におけるがんゲノムプロファイリング検査(CGP)の実施可能性の検討. 日本肺癌学会総会号. 2020. 61st
  • 荒川さやか, 吉田達哉, 元井紀子, 新野祐樹, 大熊裕介, 後藤悌, 堀之内秀仁, 山本昇, 松元祐司, 谷田部恭, et al. 肺NUT carcinomaの臨床的特徴. 日本肺癌学会総会号. 2020. 61st
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Lectures and oral presentations  (9):
  • 肺腺がんの転移活性を評価し,術後補助化学療法の効果を予測するバイオマーカーの実用化に関する後ろ向き研究 多施設共同研究
    (日本呼吸器学会誌 2021)
  • IV期原発性肺癌に対してPembrolizumab治療後にsalvage手術を施行した1例
    (肺癌 2021)
  • 特徴的な組織像を呈したROS1陽性炎症性筋線維芽細胞腫瘍の1例
    (肺癌 2020)
  • 肺癌の個別化医療-病理の立場から
    (北海道臨床細胞学会会報 2018)
  • 肺癌PD-L1 IHC検査の大規模比較検討試験:LC-SCRUM-IBIS 第一報
    (日本肺癌学会総会号 2018)
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Education (2):
  • 1992 - 1996 Graduate School of Medicine and Faculty of Medicine, the University of Tokyo Department of Pathology
  • 1986 - 1992 Kyoto Prefectural University of Medicine
Professional career (1):
  • 博士(医学) (東京大学大学院医学系研究科病因・病理学専攻)
Work history (15):
  • 2023/04 - 現在 Saitama Cancer Center Center for Cancer Genomics Director
  • 2021/04 - 現在 National Cancer Center Research Institute Visiting Researcher
  • 2021/04 - 現在 Saitama Cancer Center Department of Pathology Deputy Director
  • 2020/10 - 現在 Saitama Medical University Saitama Medical Center Pathology Visiting Associate Professor
  • 2019/04 - 2021/03 National Cancer Center Hospital Department of Diagnostic Pathology Head
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Committee career (8):
  • 2022/12 - 現在 Japan Lung Cancer Socirty Committee for International relationship
  • 2021/06 - 現在 日本臨床細胞学会 学術委員会
  • 2019/04 - 現在 Japan Pathology Society Committe for educational program of molecular pathology
  • 2018/06 - 現在 Japanese Society for Clinical Cytology Working Group on the role of Cytology in the Era of Cancer Genomic Medicine
  • 2018/02 - 現在 日本肺癌学会 ゲノム時代における呼吸器細胞診検体処理の精度管理ワーキンググループ
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Awards (1):
  • 2017/10 - Japan Endocrine Pathology Society Kameya Memorial award Pathological study of neuroendocrine tumor of the lung and other organs
Association Membership(s) (11):
International Association for the Study of Lung Cancer ,  The Japan Endocrine Society ,  Japan Endocrine Pathology Society ,  Pulmonary Pathology Society ,  The Japan Pulmonary Pathology Society ,  International Academy of Pathology ,  United States and Canadian Academy of Pathology ,  THE JAPANESE CANCER ASSOCIATION ,  Japanese Society of Clinical Cytology ,  THE JAPAN LUNG CANCER SOCIETY ,  THE JAPANESE SOCIETY OF PATHOLOGY
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