Katagiri Toyomasa

カタギリトヨマサ | Katagiri Toyomasa

Affiliation and department：
Homepage URL (1)： http://www.genome.tokushima-u.ac.jp/dgm/

Research field (2)： Pathobiochemistry , Tumor biology

Research keywords (4)：癌抑制遺伝子 , 分子標的 , ゲノム医科学 , 分子腫瘍学

Research theme for competitive and other funds (18)：

2024 - 2027 乳癌患者由来オルガノイド・動物モデルの臨床的有用性の検証と新規治療開発への応用
2023 - 2026 Mutant p53 - Cancer Immunology Research from the DDX31 axis
2022 - 2025 Development of biomarkers and new treatments for metastatic breast cancer by eribulin
2020 - 2025 Elucidating mechanisms of therapeutic resistance in breast cancer and the development of innovative therapeutic approach utilizing tumor suppressor activity
2017 - 2022 Analysis of sorting zones involved in protein quality control in the endoplasmic reticulum

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Papers (174)：

Daishiro Kobayashi, Masaya Denda, Junya Hayashi, Kota Hidaka, Yutaka Kohmura, Takaaki Tsunematsu, Kohei Nishino, Harunori Yoshikawa, Kento Ohkawachi, Kiyomi Nigorikawa, et al. Sulfoxide-Mediated Cys-Trp-Selective Bioconjugation that Enables Protein Labeling and Peptide Heterodimerization. ChemistryEurope. 2024. 2. 3-4
Jirapat Namkaew, Jun Zhang, Norio Yamakawa, Yoshimasa Hamada, Kazue Tsugawa, Miho Oyadomari, Masato Miyake, Toyomasa Katagiri, Seiichi Oyadomari. Repositioning of mifepristone as an integrated stress response activator to potentiate cisplatin efficacy in non-small cell lung cancer. Cancer letters. 2024. 582. 216509-216509
Hitomi Sudo, Atsushi B Tsuji, Aya Sugyo, Yosuke Harada, Satoshi Nagayama, Toyomasa Katagiri, Yusuke Nakamura, Tatsuya Higashi. Head-to-head comparison of three chelates reveals DOTAGA promising for 225 Ac labeling of anti-FZD10 antibody OTSA101. Cancer science. 2023. 114. 12. 4677-4690
Atsushi Saito, Yasunao Kamikawa, Taichi Ito, Koji Matsuhisa, Masayuki Kaneko, Takumi Okamoto, Tetsuro Yoshimaru, Yosuke Matsushita, Toyomasa Katagiri, Kazunori Imaizumi. p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS. Cell reports. 2023. 42. 5. 112479-112479
Makoto Takeuchi, Toshihiko Nishisho, Shunichi Toki, Shinji Kawaguchi, Shunsuke Tamaki, Takeshi Oya, Yoshihiro Uto, Toyomasa Katagiri, Koichi Sairyo. Blue light induces apoptosis and autophagy by promoting ROS-mediated mitochondrial dysfunction in synovial sarcoma. Cancer medicine. 2023. 12. 8. 9668-9683

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MISC (132)：

Abdullah S. Ili, Yosuke Matsushita, Yasuko Takahashi, Masato Komatsu, Kazuma Kiyotani, Yasuo Miyoshi, Junko Honda, Shozo Ohsumi, Mitsunori Sasa, Toyomasa Katagiri. Identification and characterization of novel susceptibility genes in hereditary Japanese familial breast cancer. CANCER SCIENCE. 2022. 113. 362-362
Yosuke Matsushita, Masato Komatsu, Kazuma Kiyotani, Takeshi Niinuma, Hiromu Suzuki, Tetsuro Yoshimaru, Atsushi Tajima, Issei Imoto, Junko Honda, Yoichi Furukawa, et al. Epigenetic alteration of SALL3 contributes to chemoresistance in triple-negative breast cancer. CANCER SCIENCE. 2022. 113. 752-752
大高章, 粟飯原圭祐, 吉丸哲郎, 片桐豊雅. Development of anti-breast cancer peptides using stapling technology. Drug Delivery System. 2020. 35. 3
安養寺啓太央, 粟飯原圭佑, 吉丸哲郎, 西川祐輔, 小松正人, 重永章, 片桐豊雅, 大高章. Development of Long-lasting Stapled Peptides Targeting BIG3-PHB2 Interaction in Breast Cancer Cell. 日本薬学会年会要旨集(CD-ROM). 2020. 140th (Web)
加藤廉平, 布川朋也, 吉丸哲郎, 松下洋輔, 尾野雅哉, 大豆本圭, 加藤陽一郎, 片桐豊雅, 小原航. 腎癌の癌化過程における新規癌特異分子PRELID2の機能解析. 日本泌尿器科学会総会. 2019. 107回. AOP-090

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Lectures and oral presentations (145)：

筋層浸潤性膀胱癌・多段階進展機構におけるDDX31の重要性
(泌尿器科分子・細胞研究会プログラム・抄録集 2024)
乳がん細胞におけるO型糖鎖修飾を介したIRE1の恒常的活性化機構の解明と新規治療戦略の可能性
(日本生化学会大会プログラム・講演要旨集 2023)
全ゲノム塩基配列決定により明らかとなった日本人家族性乳癌の新たな潜在的感受性遺伝子(Whole-exome sequencing reveals new potential susceptibility gene for Japanese familial breast cancer)
(日本癌学会総会記事 2023)
BIG3-PHB2の相互作用を標的とすることで、HER2陽性乳がんのトラスツズマブ耐性を克服できる(Targeting BIG3-PHB2 interaction overcomes trastuzumab-resistance in patients with HER2-positive breast cancer)
(日本癌学会総会記事 2023)
ゴルジ体-小胞体連携による持続的小胞体ストレス応答を通じたがん微小環境制御機構と新規創薬開発(Tumor microenvironmental control via persistent ER stress response by Golgi-ER collaboration and new therapeutics)
(日本癌学会総会記事 2023)

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Education (3)：

1998 - Osaka University Faculty of Medicine
1989 - 1991 Kagawa University Graduate School of Agriculture
1985 - 1989 Kagawa University Faculty of Agriculture

Professional career (1)：

医学博士 (大阪大学)

Work history (11)：

2023/04 - 現在 National Institutes of Biomedical Innovation, Health and Nutrition National Institutes of Biomedical Innovation
2023/04 - 2024/03 徳島大学先端酵素学研究所ゲノム医科学分野教授
2020/04 - 2023/03 Institute of Advanced Medical Sciences
2016/04 - 2023/03 徳島大学先端酵素学研究所ゲノム制御学分野教授
2012/04 - 2016/03 徳島大学疾患プロテオゲノム研究センターゲノム制御学分野教授

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