Rchr
J-GLOBAL ID：201801011606707851
Update date: Feb. 01, 2024
TZU SU MEI
ソ ミジ | TZU SU MEI
Affiliation and department：
Research field (3)：
Tumor biology
, Virology
, Immunology
Research keywords (4)：
自己免疫
, 免疫シグナル伝達
, 免疫制御・移植免疫
, 免疫監視・腫瘍免疫
Research theme for competitive and other funds (2)：
- 2022 - 2025 A novel mechanism of fibronectin/LILRB4 immune checkpoint in the regulation of the tumor microenvironment
- 2019 - 2022 The role of LILRB4 on MDSC-mediated immunosuppression in tumor environment
Papers (18)：
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Fumika Itagaki, Keita Nakatsuka, Haruka Sakai, Shota Endo, Mei-Tzu Su, Toshiyuki Takai. Fibronectin on target cells attenuates natural cytotoxicity of NK cells via myeloid immune checkpoint ILT3/LILRB4/gp49B. International Immunology. 2023. 35. 7. 339-348
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Shotaro Miyamoto, Takumi Chiba, So Itoi, Mei-Tzu Su, Toshiyuki Takai. LILRB4/gp49B Co-Localizes with Integrin via Fibronectin at Focal Adhesion Sites on Mast Cells. The Tohoku Journal of Experimental Medicine. 2023. 259. 4. 273-284
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Mei-Tzu Su, Karin Ono, Dai Kezuka, Shotaro Miyamoto, Yu Mori, Toshiyuki Takai. Fibronectin-LILRB4/gp49B interaction negatively regulates osteoclastogenesis through inhibition of RANKL-induced TRAF6/TAK1/NF-kB/MAPK signaling. International immunology. 2022
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So Itoi, Naoyuki Takahashi, Haruka Saito, Yusuke Miyata, Mei-Tzu Su, Dai Kezuka, Fumika Itagaki, Shota Endo, Hiroshi Fujii, Hideo Harigae, et al. Myeloid immune checkpoint ILT3/LILRB4/gp49B can co-tether fibronectin with integrin on macrophages. International immunology. 2022. 34. 8. 435-444
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Naoyuki Takahashi, So Itoi, Mei-Tzu Su, Shota Endo, Toshiyuki Takai. Co-localization of Fibronectin Receptors LILRB4/gp49B and Integrin on Dendritic Cell Surface. The Tohoku Journal of Experimental Medicine. 2022. 257. 3. 171-180
ｍore...
MISC (2)：
Education (1)：
Work history (3)：
- 2018/04 - 現在 東北大学加齢医学研究所
- 2017/07 - 2018/03 東北大学加齢医学研究所
- 2015/08 - 2017/04 National Taiwan University
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