2017 - 2020 Examination of factors disturbed ADCC activity of NK cells to the solid tumor
2016 - 2019 Development of CAR-T immunotherapy targeting molecule X
2014 - 2016 Identification of the HSP70 peptide for the development of cancer immunetherapy
2013 - 2016 The development of new recognition system for cancer stem cell-like cell using RNA aptamer
2012 - 2015 Development of novel immunotherapy targetimg immune checkpoint blockade for recurrent breast cancer
2012 - 2015 Suppressive role of histamine in hepatic colorectal cancer matastasis
2012 - 2015 Development of immune therapy which targets pancreatic cancer stem cells
2011 - 2013 HMGB1 is a new immunological biomarker for prognosis in patients with digestive cancer.
2011 - 2013 Augmentation of ADCC activity according to FcR polymorphisms in patients with gastric cancer who receive monoclonal antibody therapy
2009 - 2011 Cancer Immunotherapy Targeting B7-DC/ B7-H1/ PD-1 interaction May Improve Tumor Microenviroment
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Papers (212):
Yuya Hirasawa, Yutaro Kubota, Emiko Mura, Risako Suzuki, Toshiaki Tsurui, Nana Iriguchi, Tomoyuki Ishiguro, Ryotaro Ohkuma, Masahiro Shimokawa, Hirotsugu Ariizumi, et al. Maximum Efficacy of Immune Checkpoint Inhibitors Occurs in Esophageal Cancer Patients With a Low Neutrophil-to-Lymphocyte Ratio and Good Performance Status Prior to Treatment. Anticancer research. 2024. 44. 8. 3397-3407
Masakazu Murayama, Masahiro Hosonuma, Atsuo Kuramasu, Sei Kobayashi, Akiko Sasaki, Yuta Baba, Yoichiro Narikawa, Hitoshi Toyoda, Junya Isobe, Eiji Funayama, et al. Isobutyric acid enhances the anti-tumour effect of anti-PD-1 antibody. Scientific reports. 2024. 14. 1. 11325-11325
Yuta Baba, Noriko Hida, Takehiko Sambe, Maasa Abe, Nobuyuki Kabasawa, Hirotaka Sakai, Kiyoshi Yoshimura, Tetsuya Fukuda. Efficacy of Venetoclax and Azacitidine in Acute Myeloid Leukemia Compared to Azacitidine Monotherapy: Real-World Experience. Anticancer research. 2024. 44. 5. 2003-2007
Toshiaki Tsurui, Yuya Hirasawa, Yutaro Kubota, Kiyoshi Yoshimura, Takuya Tsunoda. Anti-EGFR antibody monotherapy for colorectal cancer with severe hyperbilirubinemia: A case report. World journal of gastrointestinal oncology. 2024. 16. 2. 557-562