ONO ATSUSI

オオノアツシ | ONO ATSUSI

Affiliation and department：

Research field (1)： Gastroenterology

Research theme for competitive and other funds (5)：

2022 - 2025 肝胆がんのゲノム不安定性と免疫機構の解明
2023 - 2025 “次世代型プレシジョンメディシン”を目指したNAFLDの病態解明と臨床応用
2022 - 2024 肝細胞癌における組織学的微小環境評価は免疫チェックポイント阻害剤効果予測に有用か
2020 - 2021 レンバチニブの肝癌免疫微小環境への影響についての検討
2017 - 2019 circulating tumor DNAを用いた肝癌の治療耐性獲得機序の解明

Papers (120)：

Masami Yamauchi, Atsushi Ono, Kei Amioka, Yasutoshi Fujii, Hikaru Nakahara, Yuji Teraoka, Shinsuke Uchikawa, Hatsue Fujino, Takashi Nakahara, Eisuke Murakami, et al. Lenvatinib activates anti-tumor immunity by suppressing immunoinhibitory infiltrates in the tumor microenvironment of advanced hepatocellular carcinoma. Communications medicine. 2023. 3. 1. 152-152
村上せらみ, 内田宅郎, 難波麻衣子, 藤井康智, 内川慎介, 藤野初江, 大野敦司, 中原隆志, 村上英介, 岡本渉, et al. 急性肝不全患者における血清炎症性サイトカインを含めた予後予測因子の検討. 肝臓. 2023. 64. Suppl.3. A854-A854
Ogawa, Yutaro, Nakahara, Takashi, Ando, Yuwa, Yamaoka, Kenji, Fujii, Yasutoshi, Uchikawa, Shinsuke, Fujino, Hatsue, Ono, Atsushi, Murakami, Eisuke, Kawaoka, Tomokazu, et al. Sodium-glucose cotransporter-2 inhibitors improve FibroScan-aspartate aminotransferase scores in patients with nonalcoholic fatty liver disease complicated by type 2 diabetes. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY. 2023. 35. 9. 989-996
Yosuke Tamura, Atsushi Ono, Hikaru Nakahara, Clair Nelson Hayes, Yasutoshi Fujii, Peiyi Zhang, Masami Yamauchi, Shinsuke Uchikawa, Yuji Teraoka, Takuro Uchida, et al. Association of Hepatobiliary Phase of Gadoxetic-Acid-Enhanced MRI Imaging with Immune Microenvironment and Response to Atezolizumab Plus Bevacizumab Treatment. Cancers. 2023. 15. 17
Serami Murakami, Takuro Uchida, Michio Imamura, Yosuke Suehiro, Maiko Namba, Yasutoshi Fujii, Shinsuke Uchikawa, Yuji Teraoka, Hatsue Fujino, Atsushi Ono, et al. Correlation between serum pro-inflammatory cytokine levels and the prognosis of the patients with acute liver failure. Journal of gastroenterology and hepatology. 2023

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MISC (28)：

Daiki Miki, Hiroshi Aikata, Hatsue Fujino, Atsushi Ono, Masami Yamauchi, Masataka Tsuge, Kazuaki Chayama. Genetic polymorphism in PNPLA3 is associated with hepatocellular carcinoma after hepatitis C virus eradication. CANCER SCIENCE. 2021. 112. 486-486
Atsushi Ono, Masami Yamauchi, Daiki Miki, Masataka Tsuge, Hiroshi Aikata, Kazuaki Chayama. Exploratory analysis of biomarkers associated with clinical outcomes in advanced HCC patients receiving lenvatinib. CANCER SCIENCE. 2021. 112. 530-530
Masami Yamauchi, Atsushi Ono, Daiki Miki, Masataka Tsuge, Hiroshi Aikata, Kazuaki Chayama. Tumor FGFR4 Level Predicts the Efficacy of Lenvatinib in Patients with Advanced Hepatocellular Carcinoma. CANCER SCIENCE. 2021. 112. 537-537
Tomokazu Kawaoka, Yuwa Ando, Masami Yamauchi, Yosuke Suehiro, Kenji Yamaoka, Yumi Kosaka, Yasutomo Fuji, Shinsuke Uchikawa, Kei Morio, Hatsue Fujino, et al. Reply from the authors. Hepatology Research. 2020. 50. 12. 1393
Tomokazu Kawaoka, Yuwa Ando, Masami Yamauchi, Yosuke Suehiro, Kenji Yamaoka, Yumi Kosaka, Yasutomo Fuji, Shinsuke Uchikawa, Kei Morio, Hatsue Fujino, et al. Microsatellite instability analysis using multiplex polymerase chain reaction with fluorescently labeled primers for amplification of five mononucleotide repeat markers Reply. HEPATOLOGY RESEARCH. 2020. 50. 12. 1393-1393

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Books (1)：

日本臨床最新肝臓病学
日本臨床 2015

Lectures and oral presentations (66)：

切除不能肝細胞癌に対するアテゾリズマブ+ベバシズマブ PD 症例におけるレンバチニブの治療成績について
(第45回日本肝臓学会西部会 2023)
B型慢性肝疾患患者における肝発癌予測因子としての血清 PreS1/HBsAg 比の有用性
(第45回日本肝臓学会西部会 2023)
SVR後の肝細胞癌サーベイランスにおけるaMAP,FIB-4,FIB-3の比較
(第45回日本肝臓学会西部会 2023)
切除不能肝細胞癌に対する薬物治療の変遷
(第120回日本消化器病学会中国支部例会 2023)
2型糖尿病合併 NAFLD に対する SGLT2阻害剤の有効性の検討
(第76回広島医学総会 2023)

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Work history (8)：

2019/04/01 - 2024/05/31 Hiroshima University Graduate School of Biomedical & Health Sciences Assistant Professor
2016/04/01 - 2019/03/31 Hiroshima University Hospital Department of Gastroenterology and Metabolism Assistant Professor
2016/10/01 - 2018/02/28 Icahn School of Medicine at Mount Sinai Hoshida Lab Postdoc fellow
2015/04/01 - 2016/03/31 Hiroshima University Hospital Department of Gastroenterology and Metabolism Medical Staff
2011/04/01 - 2012/03/31 Tranomon hospital Department of Hepatology medical staff

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Committee career (2)：

日本消化器病学会中国支部評議員
一般社団法人日本肝臓学会支部評議員

Awards (3)：

2015 - Liver Forum in Kyoto 研究奨励賞
日本消化器病学会 2020年度日本消化器関連学会・ポスター優秀演題賞 HCV排除後も持続するエピジェネティクス異常を介した発癌リスクの解析
日本消化器病学会 2020年度日本消化器関連学会・若手奨励賞 HCV排除後も持続するエピジェネティクス異常を介した発癌リスクの解析

Association Membership(s) (4)：

Japan Gastroenterological Endoscopy Society , the Japanese Society of Gastroenterology , the Japanese Society of Internal Medicine , the Japan Society of Hepatology

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