Rchr
J-GLOBAL ID：201801011769435239   Update date: Jan. 30, 2024

Murata Kazumoto

Murata Kazumoto
Affiliation and department：
自治医科大学 感染・免疫学講座ウイルス学部門

About 自治医科大学 感染・免疫学講座ウイルス学部門


Job title： 教授
Research field  (1)： Virology
Research theme for competitive and other funds  (13)：
  • 2022 - 2025 免疫賦活およびウイルス宿主免疫抑制機構の抑制によるB型肝炎治療の開発
  • 2017 - 2020 Basic study for HBV clearance using cytokines induced by nucleotide analogues
  • 2014 - 2017 Factors for favorable acquirement of anti-HBsAb by HBV vaccination in healthy adults
  • 2013 - 2016 The mechanism of mitochondrial injury and iron overload induced hepatocarcinogenesis in the post hepatic virus.
  • 2011 - 2014 Response and specific function of IFN-lambda3 against infectious diseases
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Papers (211)：
  • Shigeo Nagashima, Putu Prathiwi Primadharsini, Takashi Nishiyama, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto. Development of a HiBiT-tagged reporter hepatitis E virus and its utility as an antiviral drug screening platform. JOURNAL OF VIROLOGY. 2023
  • Masaharu Takahashi, Satoshi Kunita, Tsutomu Nishizawa, Hiroshi Ohnishi, Putu Prathiwi Primadharsini, Shigeo Nagashima, Kazumoto Murata, Hiroaki Okamoto. Infection Dynamics and Genomic Mutations of Hepatitis E Virus in Naturally Infected Pigs on a Farrow-to-Finish Farm in Japan: A Survey from 2012 to 2021. VIRUSES-BASEL. 2023. 15. 7
  • Kazumoto Murata, Masashi Mizokami. Possible biological mechanisms of entecavir versus tenofovir disoproxil fumarate on reducing the risk of hepatocellular carcinoma. Journal of gastroenterology and hepatology. 2023. 38. 5. 683-691
  • Putu Prathiwi Primadharsini, Shigeo Nagashima, Toshinori Tanaka, Suljid Jirintai, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto. Development and Characterization of Efficient Cell Culture Systems for Genotype 1 Hepatitis E Virus and Its Infectious cDNA Clone. VIRUSES-BASEL. 2023. 15. 4
  • Satoshi Takakusagi, Hitoshi Takagi, Yuichi Yamazaki, Takashi Kosone, Shigeo Nagashima, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto. Chronic hepatitis E in an elderly immunocompetent patient who achieved a sustained virologic response with ribavirin treatment. Clinical journal of gastroenterology. 2023. 16. 2. 206-215
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MISC (35)：
  • 須藤大輔, 吉田昌, 大竹孝明, 一石英一郎, 佐藤貴一, 村田一素, 鈴木裕, 高後裕. Effect of vonoprazan on Clinical Course of endoscopic submucosal dissection in the patients with gastric tumors. 潰瘍. 2020. 47
  • 村田一素, 前仲勝実, 溝上雅史. B型肝炎治療 2018 核酸アナログ製剤によるIFN-λ誘導とそれを標的としたB型肝炎治療薬の探索. Mebio. 2018. 35. 1. 80-87-87
  • Nao Nishida, Masaya Sugiyama, Hiromi Sawai, Sohji Nishina, Aiko Sakai, Keisuke Kakisaka, Keisuke Hino, Ryo Sumazaki, Yasuhiro Takikawa, Kazumoto Murata, et al. HLA-DRB1-DQB1 haplotypes and BTNL2 gene associate with response to a hepatitis B vaccine. HEPATOLOGY. 2017. 66. 796A-797A
  • Naohiko Masaki, Masaaki Korenaga, Mikio Yanase, Yuichi Nozaki, Shintaro Mikami, Yoshihiko Aoki, Masatoshi Imamura, Kazumoto Murata, Tatsuya Kanto, Masashi Mizokami. Effects of interferon-free treatment on serum cholesterol levels are different between the two sofosbuvir-based regimens in chronic HCV-infected patients. HEPATOLOGY. 2016. 64. 981A-981A
  • Kazumoto Murata, Akihiro Matsumoto, Masaya Sugiyama, Eiji Tanaka, Taisuke Inoue, Minoru Sakamoto, Nobuyuki Enomoto, Masao Honda, Shuichi Kaneko, Hiroyuki Gatanaga, et al. Induction of IFN-lambda 3 as an Additional Effect of Nucleotide, Not Nucleoside, Analogs: A New Potential Target for Hepatitis B Virus Infection. HEPATOLOGY. 2016. 64. 306A-306A
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Education (1)：
  • - 1988 Jichi Medical University Faculty of Medicine
Work history (1)：
  • 2020/04 - 現在 Jichi Medical University Division of Virology, Department of Infection and Immunity Professor
Association Membership(s) (5)：
American Association for the Study of Liver Diseases ,  日本消化器内視鏡学会 ,  日本内科学会 ,  日本消化器病学会 ,  日本肝臓学会
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