Horiuchi Keiko

ホリウチケイコ | Horiuchi Keiko

Affiliation and department：
Homepage URL (1)： http://dppir.com/

Research field (1)： Molecular biology

Research theme for competitive and other funds (5)：

2020 - 2023 Study of splicing factor ZRSR1 in spermatogenesis for therapeutic application
2013 - 2018 Dynamics of Molecular Pattern Recognition in Protein Interaction
2014 - 2016 Functional analysis of WTAP protein complex on alternative splicing
2008 - 2012 Dynamic Proteomics of Transcriptional and Nuclear Architecture
2008 - 2009 The Dynamics of a novel protein complex involved in RNA processing and cell cycle regulation

Papers (16)：

Hidefumi Suzuki, Kazuki Furugori, Ryota Abe, Shintaro Ogawa, Sayaka Ito, Tomohiko Akiyama, Keiko Horiuchi, Hidehisa Takahashi. MED26-containing Mediator may orchestrate multiple transcription processes through organization of nuclear bodies. BioEssays : news and reviews in molecular, cellular and developmental biology. 2023. e2200178
Isabel Gómez-Redondo, Eva Pericuesta, Paula Navarrete-Lopez, Priscila Ramos-Ibeas, Benjamín Planells, Noelia Fonseca-Balvís, Aida Vaquero-Rey, Raúl Fernández-González, Ricardo Laguna-Barraza, Keiko Horiuchi, et al. Zrsr2 and functional U12-dependent spliceosome are necessary for follicular development. iScience. 2022. 25. 2. 103860-103860
Keiko Horiuchi, Takeshi Kawamura, Takao Hamakubo. Wilms' Tumor 1-Associating Protein complex regulates alternative splicing and polyadenylation at potential G-quadruplex-forming splice site sequences. The Journal of biological chemistry. 2021. 101248-101248
Riuko Ohashi, Hajime Umezu, Ayako Sato, Tatsuya Abé, Shuhei Kondo, Kenji Daigo, Seijiro Sato, Norikazu Hara, Akinori Miyashita, Takeshi Ikeuchi, et al. Frequent Germline and Somatic Single Nucleotide Variants in the Promoter Region of the Ribosomal RNA Gene in Japanese Lung Adenocarcinoma Patients. Cells. 2020. 9. 11
Alén F, Gómez-Redondo I, Rivera P, Suárez J, Ramos-Ibeas P, Pericuesta E, Fernández-González R, Perez-Cerezales S, Horiuchi K, Orio L, et al. Sex-Dimorphic Behavioral Alterations and Altered Neurogenesis in U12 Intron Splicing-Defective Zrsr1 Mutant Mice. International journal of molecular sciences. 2019. 20. 14

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MISC (15)：

小林正稔, 大杉満, 笹子敬洋, 小林直樹, 岩根亜弥, 粟澤元晴, 岡崎由希子, 堀内恵子, 浜窪隆雄, 児玉龍彦, et al. Wilms’tumor1-associating protein(WTAP)の肥満・糖代謝への関与の検討. 糖尿病. 2012. 55. Supplement 1. S.188
小林正稔, 大杉満, 笹子敬洋, 粟澤元晴, 岡崎由希子, 堀内恵子, 浜窪隆雄, 児玉龍彦, 戸辺一之, 植木浩二郎, et al. Wilms’tumor1-associating proteinの肥満・糖代謝への関与の検討. 日本体質医学会雑誌. 2011. 73. 3. 230
小林正稔, 大杉満, 笹子敬洋, 堀内恵子, 浜窪隆雄, 戸辺一之, 植木浩二郎, 門脇孝. Wilms’ tumor1-associating proteinの肥満・糖代謝への関与の検討. 肥満研究. 2011. 17. Supplement. 149
堀内恵子, 川村猛, 浜窪隆雄. WTAP複合体の同定および機能解析(The role of WTAP complex on RNA processing and cellcycle regulation). 日本生化学会大会プログラム・講演要旨集. 2011. 84回. 4P-0412
榎本悟士, 川村猛, 岩成宏子, 太期健二, 堀内恵子, 南敬, 児玉龍彦, 浜窪隆雄. CDGAPはROBO1と相互作用して血管内皮細胞のSLIT2依存的な遊走に関与する。. 生化学. 2010. 83回・33回. ROMBUNNO.3P-0186-0186

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Education (3)：

2002 - 2005 The University of Tokyo
1998 - 2002 The University of Tokyo
1996 - 1998 東京大学理科II類

Professional career (1)：

Ph.D. (University of Tokyo)

Work history (8)：

2021/08 - 現在 Yokohama City University School of Medicine Medical Course Molecular Biology
2021/04 - 2021/07 Nippon Medical School
2018/04 - 2021/03 Nippon Medical School Institute for Advanced Medical Sciences Assistant professor
2014/07 - 2018/03 The University of Tokyo
2014/04 - 2017/09 Center for Genomic Regulaton, Barcelona, Spain

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