Rchr
J-GLOBAL ID：201801011917734356
Update date: Jun. 08, 2020
Miyazaki Yu
ミヤザキ ユウ | Miyazaki Yu
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Affiliation and department：
Osaka University Graduate School of Medicine Division of Medicine
About Osaka University Graduate School of Medicine Division of Medicine
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Job title：
Assistant Professor
Homepage URL (1)：
http://www.med.osaka-u.ac.jp/pub/rna/p_miyazaki.html
Research field (2)：
Neurology
, Neuroanatomy and physiology
Research keywords (3)：
Neurodegenerative diseases
, RNA metabolism
, Therapy development
Research theme for competitive and other funds (2)：
2018 - 挑戦的研究(萌芽)
2017 - 2018 研究活動スタート支援
Papers (14)：
Yu Miyazaki, Xiaofei Du, Shin-ichi Muramatsu, Christopher M. Gomez. An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron. SCIENCE TRANSLATIONAL MEDICINE. 2016. 8. 347
Madoka Iida, Masahisa Katsuno, Hideaki Nakatsuji, Hiroaki Adachi, Naohide Kondo, Yu Miyazaki, Genki Tohnai, Kensuke Ikenaka, Hirohisa Watanabe, Masahiko Yamamoto, et al. Pioglitazone suppresses neuronal and muscular degeneration caused by polyglutamine-expanded androgen receptors. HUMAN MOLECULAR GENETICS. 2015. 24. 2. 314-329
Genki Tohnai, Hiroaki Adachi, Masahisa Katsuno, Hideki Doi, Shinjiro Matsumoto, Naohide Kondo, Yu Miyazaki, Madoka Iida, Hideaki Nakatsuji, Qiang Qiang, et al. Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy. HUMAN MOLECULAR GENETICS. 2014. 23. 13. 3552-3565
Toshika Ohkawa, Shin'Ichiro Satake, Norihiko Yokoi, Yu Miyazaki, Tomohiko Ohshita, Gen Sobue, Hiroshi Takashima, Osamu Watanabe, Yuko Fukata, Masaki Fukata. Identification and Characterization of GABA(A) Receptor Autoantibodies in Autoimmune Encephalitis. JOURNAL OF NEUROSCIENCE. 2014. 34. 24. 8151-8163
Qiang Qiang, Hiroaki Adachi, Zhe Huang, Yue-Mei Jiang, Masahisa Katsuno, Makoto Minamiyama, Hideki Doi, Shinjiro Matsumoto, Naohide Kondo, Yu Miyazaki, et al. Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease. JOURNAL OF NEUROCHEMISTRY. 2013. 126. 1. 122-130
ｍore...
MISC (4)：
宮崎 雄. 難病の遺伝子治療の最前線 脊髄小脳失調症. 難病と在宅ケア. 2019. 24. 12. 12-15
宮崎 雄. トリプレットリピート病におけるRAN翻訳の関与. 医学のあゆみ. 2018. 267. 12
宮崎 雄, 祖父江 元. miRNA搭載ウイルスベクターによる球脊髄性筋萎縮症の治療展望. 神経内科. 2013
宮崎 雄, 祖父江 元. ウイルスによるmiR-196aの遺伝子導入はCELF2の発現抑制を介し球脊髄性筋萎縮症の表現型を改善する. ライフサイエンス新着論文レビュー. 2012
Patents (1)：
Developing a Novel miRNA-Mediated Therapeutic Approach for Spinocerebellar Ataxia Type 6 (“INVENTION”)
Lectures and oral presentations (4)：
miRNA-mediated Therapeutic Approaches for Neurodegenerative Diseases
(22nd US-Japan Cellular and Gene Therapy Conference 2019)
miRNA-mediated therapeutic approaches for neurodegenerative diseases.
(第59回日本神経学会学術大会 2018)
AAV-miRNAによる神経疾患の遺伝子治療
(第23回日本遺伝子細胞治療学会学術集会 2017)
Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2.
(第5回NAGOYAグローバルリトリート ブレークスルーリサーチアワード受賞記念講演 2013)
Education (2)：
2009 - 2012 Nagoya University Graduate School of Medicine Cellular Information Medicine
1998 - 2004 Nagoya University School of Medicine
Professional career (1)：
医学博士 (名古屋大学)
Work history (6)：
2017/04 - 現在 Osaka University Graduate School of Medicine
2014/05 - 米国シカゴ大学 神経内科学 ポスドク研究員
2012/10 - Nagoya University Graduate School of Medicine
2008/04 - 総合病院中津川市民病院 神経内科 医師
2006/04 - 名古屋第一赤十字病院 神経内科 医師
2004/04 - 名古屋第一赤十字病院 研修医
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Awards (3)：
2015/01 - National Ataxia Foundation Post-Doc Fellowship Award(米国)
2014/09 - Lilly Scientific Fellowship Program Award
2013/02 - Global COEブレークスルーリサーチアワード
Association Membership(s) (4)：
Society for Neuroscience
, THE JAPAN NEUROSCIENCE SOCIETY
, JAPANESE SOCIETY OF NEUROLOGY
, THE JAPANESE SOCIETY OF INTERNAL MEDICINE
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