Wataru Shihoya

Affiliation and department：

Research field (1)： Structural biochemistry

Research theme for competitive and other funds (4)：

2022 - 2026 Structural analysis and drug development of GPCRs
2020 - 2023 非古典的ロドプシンの構造機能解析
2020 - 2022 TR-SFX study of non-canonical rhodopsin
2018 - 2020 Structural analysis of endothelin receptors in complex with G-proteins

Papers (32)：

Wataru Shihoya, Aika Iwama, Fumiya K Sano, Osamu Nureki. Cryo-EM advances in GPCR structure determination. Journal of biochemistry. 2024
Tamaki Izume, Ryo Kawahara, Akiharu Uwamizu, Luying Chen, Shun Yaginuma, Jumpei Omi, Hiroki Kawana, Fengjue Hou, Fumiya K. Sano, Tatsuki Tanaka, et al. Structural basis for lysophosphatidylserine recognition by GPR34. Nature Communications. 2024. 15. 1
Jagannath Maharana, Fumiya K Sano, Parishmita Sarma, Manish K Yadav, Longhan Duan, Tomasz M Stepniewski, Madhu Chaturvedi, Ashutosh Ranjan, Vinay Singh, Sayantan Saha, et al. Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors. Science (New York, N.Y.). 2024. 383. 6678. 101-108
Hidetaka S. Oshima, Fumiya K. Sano, Hiroaki Akasaka, Aika Iwama, Wataru Shihoya, Osamu Nureki. Optimizing Cryo-EM Structural Analysis of Gi-coupling Receptors via Engineered Gtand Nb35 Application. 2023
Wataru Shihoya, Fumiya K Sano, Osamu Nureki. Structural insights into endothelin receptor signalling. Journal of biochemistry. 2023. 174. 4. 317-325

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MISC (33)：

小林和弘, 川上耕季, 草木迫司, 郷野弘剛, 富田敦弘, 小林幹, 志甫谷渉, 山下恵太郎, 西澤知宏, 加藤英明, et al. PTH1受容体における内在性リガンドの認識機構と構造ダイナミクス. 日本生化学会大会プログラム・講演要旨集. 2022. 95回. 2T12a-07
Kawahara Ryo, Sano Fumiya, Uwamizu Akiharu, Chen Luying, Ohwada Tomohiko, Aoki Junken, Shihoya Wataru, Nureki Osamu. 代謝安定型作動薬とLysoPS受容体LPS1の構造解析(Cryo-EM structure of LysoPS Receptor LPS1 in complex with Metabolically Stable Agonist). 生物物理. 2022. 62. Suppl.1-2. S268-S268
Nakamura Sotaro, Yamazaki Hirohito, Shihoya Wataru, Nureki Osamu, Uemura Sotaro. ナノポア計測によるCALHM2チャネルダイナミクスの解明(Investigation of CALHM2 Channel Dynamics using Nanopore measurement). 生物物理. 2022. 62. Suppl.1-2. S334-S334
Akasaka Hiroaki, Tanaka Tatsuki, Sano Fumiya, Shihoya Wataru, Nureki Osamu. クライオ電子顕微鏡によるヒトLPA1受容体の構造解析(Cryo-EM structure of Human Lysophosphatidic Acid Receptor 1). 生物物理. 2022. 62. Suppl.1-2. S346-S346
Okamoto Hiroyuki, Miyauchi Hirotake, Inoue Asuka, Raimondi Francesco, Tsujimoto Hirokazu, Kusakizako Tsukasa, Shihoya Wataru, Yamashita Keitaro, Suno Ryoji, Nomura Norimichi, et al. クライオ電子顕微鏡によるヒト由来メラトニン受容体シグナル伝達複合体の立体構造解析(Cryo-EM structure of the human MT1-Gi signaling complex). 生物物理. 2022. 62. Suppl.1-2. S347-S347

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Professional career (1)：

創薬科学 (名古屋大学)

Awards (15)：

2022/12 - 一般社団法人化学情報協会 JAICI賞
2022/11 - The 15th International Symposium on VIP, PACAP and Related Peptides Akira Arimura Award
2022/11 - 日本生化学会令和4年度生化学会奨励賞
2022/05 - 令和4年度花王研究奨励賞
2022/04 - 令和4年度文部科学大臣若手科学者賞

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