Rchr
J-GLOBAL ID：201801012260883972   Update date: Sep. 13, 2024

Amo Taku

アモウ タク | Amo Taku
Affiliation and department：
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Research keywords  (4)： respiratory chain ,  neurodegenerative disease ,  Parkinson's disease ,  mitochondria
Research theme for competitive and other funds  (19)：
  • 2023 - 2026 ミトコンドリア呼吸鎖障害によるパーキンソン病ドパミン神経特異的変性の分子機構
  • 2022 - 2025 ミトコンドリアプロテオスタシスに着眼した凝集体形成機序の解明
  • 2020 - 2023 遺伝性パーキンソン病におけるドーパミン神経特異的ミトコンドリア機能障害の分子機構
  • 2019 - 2022 ミトコンドリア直接刺激によるメカノセンサの探索
  • 2018 - 2022 Identification of Parkinson's disease progression markers based on skeletal muscle-brain axis
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Papers (34)：
  • Kazuhiro Nomura, Shinichi Kinoshita, Nao Mizusaki, Yoko Senga, Tsutomu Sasaki, Tadahiro Kitamura, Hiroshi Sakaue, Aki Emi, Tetsuya Hosooka, Masahiro Matsuo, et al. Adaptive gene expression of alternative splicing variants of PGC-1α regulates whole-body energy metabolism. Molecular metabolism. 2024. 86. 101968-101968
  • Aya Ikeda, Hongrui Meng, Daisuke Taniguchi, Muneyo Mio, Manabu Funayama, Kenya Nishioka, Mari Yoshida, Yuanzhe Li, Hiroyo Yoshino, Tsuyoshi Inoshita, et al. CHCHD2 P14L, found in amyotrophic lateral sclerosis, exhibits cytoplasmic mislocalization and alters Ca2+ homeostasis. PNAS nexus. 2024. 3. 8. pgae319
  • Takahiro Takekiyo, Natsuki Yamada, Taku Amo, Chikako T. Nakazawa, Atushi Asano, Tohru Ichimura, Minoru Kato, Yukihiro Yoshimura. Dissolution of amyloid aggregates by direct addition of alkali halides. JOURNAL OF MOLECULAR LIQUIDS. 2023. 369
  • Takahiro Takekiyo, Natsuki Yamada, Taku Amo, Atsushi Asano, Yukihiro Yoshimura. Triiodide ion-induced inhibition of amyloid aggregate formation: A case study of α-synuclein. Journal of Molecular Liquids. 2022. 360
  • Takeshi Tokuyama, Hideki Uosaki, Ayumu Sugiura, Gen Nishitai, Keisuke Takeda, Shun Nagashima, Isshin Shiiba, Naoki Ito, Taku Amo, Satoshi Mohri, et al. Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation. iScience. 2022. 25. 7. 104582-104582
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MISC (10)：
  • Baba Megumi, Shinmura Aya, Takemura Koki, Simizu Keigo, Amo Taku, Tsukamoto Akira, Tada Shigeru. 1D14 Mitochondria dynamics in vascular endothelial cells under cyclic stretches. 2016. 2016. 28. "1D14-1"-"1D14-4"
  • 舩山学, 舩山学, 舩山学, 大江賢治, 大江賢治, 天羽拓, 古屋徳彦, 山口隼司, 斉木臣二, 李元哲, et al. 新規パーキンソン病原因遺伝子CHCHD2の単離. 日本ミトコンドリア学会年会要旨集. 2015. 15th. 80
  • Baba Megumi, Tsukamoto Akira, Shinmura Aya, Takemura Koki, Amo Taku, Ushida Takashi, Tada Shigeru. PS2-16 Mitochondria dynamics in human aortic endothelial cells under supra-physiologic level cyclic stretches(PS2: Poster Short Presentation II,Poster Session). Proceedings of the ... Asian Pacific Conference on Biomechanics : emerging science and technology in biomechanics. 2015. 2015. 8. 258-258
  • Taku Amo, Shigeto Sato, Shinji Saiki, Alexander M. Wolf, Masaaki Toyomizu, Clement A. Gautier, Jie Shen, Shigeo Ohta, Nobutaka Hattori. Mitochondrial membrane potential decrease caused by loss of PINK1 is not due to proton leak, but to respiratory chain defects. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS. 2012. 1817. S78-S78
  • 佐藤 栄人, 天羽 拓, 斉木 臣二, Wolf Alexander, 豊水 正昭, Gautier Clement, Shen Jie, 太田 茂男, 服部 信孝. PINK1ノックアウトMEFのミトコンドリア機能解析. 臨床神経学. 2011. 51. 12. 1223-1223
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Education (3)：
  • 2001 - 2004 京都大学大学院 工学研究科 合成・生物化学専攻 博士後期課程
  • 1999 - 2001 京都大学大学院 工学研究科 合成・生物化学専攻 修士課程
  • 1995 - 1999 Kyoto Univ.
Work history (7)：
  • 2020/10 - 現在 National Defense Academy
  • 2015/04 - 2020/09 National Defense Academy
  • 2009/10 - 2015/03 National Defense Academy
  • 2009/04 - 2009/09 JSPS Research Fellow - PD
  • 2007/04 - 2009/09 Nippon Medical School
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Association Membership(s) (3)：
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE JAPANESE SOCIETY OF MITOCHONDRIAL RESEARCH AND MEDICINE
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