Research field (3):
Conservative dentistry and endodontics
, Oral medicine (pathology)
, Oral medicine
Research keywords (2):
免疫学
, 細菌学
Research theme for competitive and other funds (6):
2023 - 2024 低酸素誘導因子による炎症制御・創傷治癒メカニズムの解析
2019 - 2021 低酸素誘導性因子を用いた肺炎制御法の開発
2018 - 2020 炎症誘導能の網羅的解析に基づく新たな肺炎球菌の病原因子の同定
2018 - 2019 細菌性肺炎制御に向けた,コメ由来ペプチドの探索および機能解析
2018 - 2019 抗炎症タンパク質Del-1を用いた肺炎重症化抑制効果の検討
2018 - 2018 肺炎球菌の菌体内病原因子の検索-高齢者誤嚥性肺炎の分子制御を目指して-
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Papers (21):
Hui Wang, Xiaofei Li, Tetsuhiro Kajikawa, Jieun Shin, Jong-Hyung Lim, Ioannis Kourtzelis, Kosuke Nagai, Jonathan Korostoff, Sylvia Grossklaus, Ronald Naumann, et al. Stromal cell-derived DEL-1 inhibits Tfh cell activation and inflammatory arthritis. The Journal of clinical investigation. 2021
Kosuke Nagai, Hidetaka Ideguchi, Tetsuhiro Kajikawa, Xiaofei Li, Triantafyllos Chavakis, Jing Cheng, Phillip B Messersmith, Ellen Heber-Katz, George Hajishengallis. An injectable hydrogel-formulated inhibitor of prolyl-4-hydroxylase promotes T regulatory cell recruitment and enhances alveolar bone regeneration during resolution of experimental periodontitis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020. 34. 10. 13726-13740
Toshihito Isono, Hisanori Domon, Kosuke Nagai, Tomoki Maekawa, Hikaru Tamura, Takumi Hiyoshi, Katsunori Yanagihara, Eiji Kunitomo, Shoji Takenaka, Yuichiro Noiri, et al. Treatment of severe pneumonia by hinokitiol in a murine antimicrobial-resistant pneumococcal pneumonia model. PloS one. 2020. 15. 10. e0240329
The role of Azin2 in macrophage efferocytosis and resolution of inflammation
(3rd International Conference on Oral Mucosal Immunity and Microbiome 2023)
Azin2 promotes macrophage efferocytosis and resolution of inflammation
(17th International Conference on Innate Immunity 2022)
Immunization with pneumococcal EF-Tu enhances serotype-independent protection against <i>Streptococcus pneumoniae</i>
(第92回日本細菌学会 2019)