Nagai Kosuke

ナガイコウスケ | Nagai Kosuke

Affiliation and department：
Job title：ポスドク
Homepage URL (1)： https://tu-dresden.de/med/mf/plid/forschung/Chavakis

Research field (3)： Conservative dentistry and endodontics , Oral medicine (pathology) , Oral medicine

Research keywords (2)：免疫学 , 細菌学

Research theme for competitive and other funds (6)：

2023 - 2024 低酸素誘導因子による炎症制御・創傷治癒メカニズムの解析
2019 - 2021 低酸素誘導性因子を用いた肺炎制御法の開発
2018 - 2020 炎症誘導能の網羅的解析に基づく新たな肺炎球菌の病原因子の同定
2018 - 2019 細菌性肺炎制御に向けた,コメ由来ペプチドの探索および機能解析
2018 - 2019 抗炎症タンパク質Del-1を用いた肺炎重症化抑制効果の検討

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Papers (21)：

Hui Wang, Xiaofei Li, Tetsuhiro Kajikawa, Jieun Shin, Jong-Hyung Lim, Ioannis Kourtzelis, Kosuke Nagai, Jonathan Korostoff, Sylvia Grossklaus, Ronald Naumann, et al. Stromal cell-derived DEL-1 inhibits Tfh cell activation and inflammatory arthritis. The Journal of clinical investigation. 2021
Kosuke Nagai, Hidetaka Ideguchi, Tetsuhiro Kajikawa, Xiaofei Li, Triantafyllos Chavakis, Jing Cheng, Phillip B Messersmith, Ellen Heber-Katz, George Hajishengallis. An injectable hydrogel-formulated inhibitor of prolyl-4-hydroxylase promotes T regulatory cell recruitment and enhances alveolar bone regeneration during resolution of experimental periodontitis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020. 34. 10. 13726-13740
Toshihito Isono, Hisanori Domon, Kosuke Nagai, Tomoki Maekawa, Hikaru Tamura, Takumi Hiyoshi, Katsunori Yanagihara, Eiji Kunitomo, Shoji Takenaka, Yuichiro Noiri, et al. Treatment of severe pneumonia by hinokitiol in a murine antimicrobial-resistant pneumococcal pneumonia model. PloS one. 2020. 15. 10. e0240329
日吉巧, 土門久哲, 前川知樹, 永井康介, 田村光, 高橋直紀, 吉田明弘, 寺尾豊, 多部田康一. Aggregatibacter actinomycetemcomitansによる歯周炎重症化メカニズムの解析. 日本歯周病学会会誌. 2019. 61. 春季特別. 124-124
Kosuke Nagai, Osamu Kimura, Hisanori Domon, Tomoki Maekawa, Daisuke Yonezawa, Yutaka Terao. Antimicrobial susceptibility of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis clinical isolates from children with acute otitis media in Japan from 2014 to 2017. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2019. 25. 3. 229-232

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MISC (12)：

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Lectures and oral presentations (10)：

The role of Azin2 in macrophage efferocytosis and resolution of inflammation
(3rd International Conference on Oral Mucosal Immunity and Microbiome 2023)
Azin2 promotes macrophage efferocytosis and resolution of inflammation
(17th International Conference on Innate Immunity 2022)
Immunization with pneumococcal EF-Tu enhances serotype-independent protection against <i>Streptococcus pneumoniae</i>
(第92回日本細菌学会 2019)
肺炎球菌性肺炎の病態発症メカニズムの解析と新規肺炎予防法への展開
(第51回新潟歯学会総会 2018)
Pneumococcal DNA-binding proteins released through autolysis induce inflammatory cytokine production via toll-like receptor 4
(第91回日本細菌学会 2018)

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Education (2)：

2015 - 2019 Niigata University Graduate School of Medical and Dental Sciences
2008 - 2014 Tohoku University Faculty of Dentistry Department of Dentistry

Work history (6)：

2023/01 - 現在 Japan Society for the Promotion of Science
2019/08 - 現在ドイツドレスデン工科大学医学部ポスドク
2019/05 - 2019/07 Niigata University Institute for Research Promotion
2019/04 - 2019/04 Niigata University Graduate School of Medical and Dental Sciences
2018/04 - 2019/03 米国ペンシルバニア大学歯学部客員研究員

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Awards (3)：

2023/10 - 3rd International Conference on Oral Mucosal Immunity and Microbiome Travel Award
2019/04 - 日本細菌学会優秀発表賞
2019/02 - 新潟歯学会新潟歯学会賞

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