Rchr
J-GLOBAL ID:201801012380736060   Update date: May. 05, 2021

Hattori Shinichiro

Hattori Shinichiro
Research field  (1): Virology
Research theme for competitive and other funds  (2):
  • 2020 - 2023 HIVとHBVの逆転写酵素の構造比較・解析を基盤とした新規抗HBV薬開発への応用
  • 2012 - 2012 HIV感染モデルマウスを用いたHIV感染早期におけるNK細胞の動態解明
Papers (45):
  • Kenji Maeda, Nobuyo Higashi-Kuwata, Noriko Kinoshita, Satoshi Kutsuna, Kiyoto Tsuchiya, Shin-Ichiro Hattori, Kouki Matsuda, Yuki Takamatsu, Hiroyuki Gatanaga, Shinichi Oka, et al. Neutralization of SARS-CoV-2 with IgG from COVID-19-convalescent plasma. Scientific reports. 2021. 11. 1. 5563-5563
  • Seiya Yamayoshi, Atsuhiro Yasuhara, Mutsumi Ito, Osamu Akasaka, Morio Nakamura, Ichiro Nakachi, Michiko Koga, Keiko Mitamura, Kazuma Yagi, Kenji Maeda, et al. Antibody titers against SARS-CoV-2 decline, but do not disappear for several months. EClinicalMedicine. 2021. 32. 100734-100734
  • Shin-Ichiro Hattori, Nobuyo Higashi-Kuwata, Hironori Hayashi, Srinivasa Rao Allu, Jakka Raghavaiah, Haydar Bulut, Debananda Das, Brandon J Anson, Emma K Lendy, Yuki Takamatsu, et al. A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication. Nature communications. 2021. 12. 1. 668-668
  • Nobuyo Higashi-Kuwata, Sanae Hayashi, Hiroki Kumamoto, Hiromi Ogata-Aoki, Debananda Das, David Venzon, Shin-Ichiro Hattori, Haydar Bulut, Mai Hashimoto, Masaki Otagiri, et al. Identification of a novel long-acting 4'-modified nucleoside reverse transcriptase inhibitor against HBV. Journal of hepatology. 2020
  • Shin-Ichiro Hattori, Nobuyo Higshi-Kuwata, Jakka Raghavaiah, Debananda Das, Haydar Bulut, David A Davis, Yuki Takamatsu, Kouki Matsuda, Nobutoki Takamune, Naoki Kishimoto, et al. GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection. mBio. 2020. 11. 4
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MISC (18):
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Lectures and oral presentations  (2):
  • 極めて強力な抗HIV活性を発揮する新規プロテアーゼ阻害剤GRL-142/KU-241の同定及びそのSIVmac251感染サルにおける抗ウイルス効果
    (日本エイズ学会誌 2018)
  • HIV潜伏感染細胞を標的とした新規治療薬開発に有効なin vitro評価系の開発
    (日本エイズ学会誌 2017)
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