Rchr
J-GLOBAL ID:201801012652482356   Update date: Nov. 18, 2024

Sakamoto Eijiro

Sakamoto Eijiro
Affiliation and department:
Job title: Senior Assistant Professor
Research field  (2): Oral medicine (pathology) ,  Metabolism and endocrinology
Research keywords  (5): Osteocytes ,  bone and mineral metabolism ,  advanced glycation end-products ,  diabetes mellitus ,  periodontitis
Research theme for competitive and other funds  (6):
  • 2024 - 2027 上皮細胞のピロトーシス様細胞死抑制による歯周炎発症予防法の開発
  • 2024 - 2027 インフラマソームプライミングを指標とした歯周病と全身疾患の分子生物学的関連解析
  • 2017 - 2020 糖尿病患者の口腔保健行動アセスメントシートを用いた看護支援プログラムの開発
  • 2019 - 2020 糖尿病関連歯周炎における骨細胞ギャップ結合を介した細胞間情報伝達機構の解明
  • 2016 - 2019 最終糖化産物とリポ多糖による骨細胞スクレロスチンの発現調節と骨代謝への影響
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Papers (33):
  • Eijiro Sakamoto, Yukiko Kitase, Alexander J Fitt, Zewu Zhu, Kamal Awad, Marco Brotto, Kenneth E White, Steven S Welc, Clemens Bergwitz, Lynda F Bonewald. Both enantiomers of β-aminoisobutyric acid BAIBA regulate Fgf23 via MRGPRD receptor by activating distinct signaling pathways in osteocytes. Cell reports. 2024. 43. 7. 114397-114397
  • 尾崎 幸生, Elazegui Ralph, 前 めぐみ, 大平 真之, 一瀬 早紀, 上田 明日香, 山下 恭徳, 坂本 英次郎, 柳口 嘉治郎, 吉村 篤利. 人口歯石によるラット実験的歯周炎の骨吸収促進について. 日本歯周病学会会誌. 2023. 65. 秋季特別. 128-128
  • Rie Kido, Jun-Ichi Kido, Yasufumi Nishikawa, Eijiro Sakamoto, Yoritoki Tomotake, Hiromichi Yumoto. Diagnosis of inflammatory peri-implant diseases using an immunochromatographic assay for calprotectin in peri-implant crevicular fluid. International journal of implant dentistry. 2021. 7. 1. 106-106
  • Yuji Inagaki, Jun-Ichi Kido, Yasufumi Nishikawa, Rie Kido, Eijiro Sakamoto, Mika Bando, Koji Naruishi, Toshihiko Nagata, Hiromichi Yumoto. Gan-Lu-Yin (Kanroin), Traditional Chinese Herbal Extracts, Reduces Osteoclast Differentiation In Vitro and Prevents Alveolar Bone Resorption in Rat Experimental Periodontitis. Journal of clinical medicine. 2021. 10. 3
  • Eijiro Sakamoto, Yuka Hiroshima, Jun-ichi Kido, Yasufumi Nishikawa, Koji Naruishi, Rie Kido, Hiromichi Yumoto. Various roles of calprotectin in periodontal disease and its possibility as a diagnostic marker for periodontal disease. Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology). 2020. 62. 4. 193-199
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MISC (9):
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Lectures and oral presentations  (39):
  • Advanced glycation end-products inhibit cell to cell communication in osteocytes with diabetes
    (2024)
  • Advanced glycation end-products inhibit pannexin3 expression in osteocytes under the diabetic condition
    (ASBMR annual meeting 2024 2024)
  • b-aminoisobutyric acid, BAIBA elevates Fgf23 expression in osteocytes through distinct mechanisms
    (ASBMR annual meeting 2022 2022)
  • The L/S enantiomer of beta aminoisobutyric acid, BAIBA, induces FGF23 expression in osteocytes in vivo, in isolated primary osteocytes and IDG-SW3 cells through the MRGPRD/Gs/cAMP/-catenin signaling pathway
    (ASBMR annual meeting 2021 2021)
  • S100A9 は MAPK および STAT3 経路を介して骨細胞における IL-6 と RANKL の発現を調節する
    (第150回春季日本歯科保存学会学術大会 2019)
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Awards (2):
  • 2020/02 - 日本歯科保存学会 日本歯科保存学会奨励賞 終末糖化産物と LPS は骨細胞由来スクレロスチンを介し骨芽細胞分化を抑制する
  • 2016/09/18 - Japan Academy of Diabetes Education and Nursing 第21回日本糖尿病教育・看護学会学術集会 JADEN21 AWARD JADEN 21st AWARD
Association Membership(s) (3):
American Society for Bone and Mineral Research ,  Japanese Society of Conservative Dentistry ,  Japanese Society of Periodontology
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