Tajima Ken

Affiliation and department：

Research field (2)： Tumor diagnostics and therapeutics , Respiratory medicine

Research keywords (7)：細胞老化 , 抗がん剤耐性 , 上皮間葉転換 , ヒストンメチル化 , エピジェネティクス , 肺がん , 中皮腫

Research theme for competitive and other funds (15)：

2023 - 2029 可逆性分化モデルによる腫瘍内不均一性の解明と薬剤耐性克服
2023 - 2027 薬剤耐性クローンに着目した腫瘍内不均一性と薬剤耐性原理の解明
2023 - 2027 薬剤耐性クローンに着目した腫瘍内不均一性と薬剤耐性原理の解明
2023 - 2026 エピジェネティクスの再構成の追跡による老化細胞の分類構築と新規治療法開発への挑戦
2023 - 2026 肺癌における酸化ストレス応答系の新規破綻機序の解明と標的治療の探索

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Papers (46)：

Yosuke Miyashita, Ken Tajima, Kenta Izumi, Naohisa Matsumoto, Daisuke Hayakawa, Ikuko Takeda Nakamura, Isana Katayama, Adityo Wibowo, Hironari Matsuda, Wira Winardi, et al. Novel Approach to Overcome Osimertinib Resistance Using Bromodomain and Extra-Terminal Domain Inhibitors. Cancer science. 2025
Yoshihiro Masui, Takehito Shukuya, Shunichi Kataoka, Hitomi Shiozaki, Kana Kurokawa, Ikuko Nakamura, Taichi Miyawaki, Yoshika Koinuma, Tetsuhiko Asao, Ryota Kanemaru, et al. Second malignancy in advanced or recurrent non-small cell lung cancer after the advent of molecular targeted drugs and immunotherapy. Thoracic cancer. 2024
Yoshika Koinuma, Yoichiro Mitsuishi, Wira Winardi, Moulid Hidayat, Aditya Wirawan, Daisuke Hayakawa, Koichiro Kanamori, Naohisa Matsumoto, Takuo Hayashi, Naoko Shimada, et al. Anti-Müllerian hormone type II receptor protein expression in non-small cell lung cancer and the effect of AMH/AMHR2 signaling on cancer cell proliferation. Thoracic cancer. 2024
Naohisa Matsumoto, Ken Tajima, Fumiyuki Takahashi, Yoichiro Mitsuishi, Aditya Wirawan, Moulid Hidayat, Wira Winardi, Adityo Wibowo, Daisuke Hayakawa, Kenta Izumi, et al. Clinical potential of SKP2 as diagnostic marker and therapeutic target in small cell lung cancer. Respiratory investigation. 2024. 62. 5. 901-909
Kana Kurokawa, Tetsuhiko Asao, Takuo Hayashi, Satsuki Kishikawa, Koichiro Kanamori, Takehito Shukuya, Yosuke Miyashita, Ikuko Nakamura, Taichi Miyawaki, Ryota Kanemaru, et al. Trophoblast Cell Surface Antigen 2 Expression in Thymic Carcinoma: Brief Report. JTO clinical and research reports. 2024. 5. 7. 100693-100693

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MISC (24)：

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Professional career (1)：

博士 (順天堂大学)

Work history (1)：

2021/05 - 現在順天堂大学医学部・大学院医学研究科呼吸器内科准教授

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