Shi Shoi

Affiliation and department：

Research field (4)： Systems genomics , Neuroscience - general , Neuroscience - general , Physiology

Research keywords (4)：神経科学 , Infectious diseases , Sleep , Theoretical biology

Research theme for competitive and other funds (10)：

2022 - 2029 Deciphering the mysteries of sleep:creating a global network of sleep neurobiologists
2023 - 2026 Understanding the mechanism of the sleep-wake cycle regulation in the cross-talk between molecules and cells
2023 - 2026 比較神経科学でひも解くREMレム睡眠の共通原理
2023 - 2025 環境的要因による睡眠表現型の多様化機序の理解
2020 - 2025 Glia decoding: deciphering information critical for brain-body interactions

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Papers (40)：

Takeshi Sawada, Yusuke Iino, Kensuke Yoshida, Hitoshi Okazaki, Shinnosuke Nomura, Chika Shimizu, Tomoki Arima, Motoki Juichi, Siqi Zhou, Nobuhiro Kurabayashi, et al. Prefrontal synaptic regulation of homeostatic sleep pressure revealed through synaptic chemogenetics. Science (New York, N.Y.). 2024. 385. 6716. 1459-1465
Kazuhiro Kon, Koji L Ode, Tomoyuki Mano, Hiroshi Fujishima, Riina R Takahashi, Daisuke Tone, Chika Shimizu, Shinnosuke Shiono, Saori Yada, Kyoko Matsuzawa, et al. Cortical parvalbumin neurons are responsible for homeostatic sleep rebound through CaMKII activation. Nature communications. 2024. 15. 1. 6054-6054
Naoki Okada, Yutaka Umemura, Shoi Shi, Shusuke Inoue, Shun Honda, Yohsuke Matsuzawa, Yuichiro Hirano, Ayano Kikuyama, Miho Yamakawa, Tomoko Gyobu, et al. "KAIZEN" method realizing implementation of deep-learning models for COVID-19 CT diagnosis in real world hospitals. Scientific reports. 2024. 14. 1. 1672-1672
Yimeng Wang, Siyu Cao, Daisuke Tone, Hiroshi Fujishima, Rikuhiro G. Yamada, Rei-ichiro Ohno, Shoi Shi, Kyoko Matsuzawa, Mari Kaneko, Maki Ukai-Tadenuma, et al. Post-synaptic competition between calcineurin and PKA regulates mammalian sleep-wake cycles. 2023
Ryo Kinoshita, Miho Sassa, Shogo Otake, Fumi Yoshimatsu, Shoi Shi, Ryo Ueno, Motoi Suzuki, Daisuke Yoneoka. Impact of airline network on the global importation risk of mpox, 2022. Epidemiology and infection. 2023. 151. e60

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MISC (6)：

バイエステロッチマリアネウス, 史蕭逸, 戸根大輔, 大出晃士, 藤島博史, 山田陸裕, 隅山健太, 上田泰己. Investigating roles of pore-loop cation channels for cortical neuronal synchrony and sleep quality and time. 時間生物学. 2023. 29. 2
米岡大輔, 野村周平, ギルモースチュアート, 斎藤英子, 田上悠太, 川島孝行, 史蕭逸, 江口哲史. コロナ禍における迅速サーベイランスを用いたビッグデータ解析における機械学習・統計学的方法論の整備. 大和証券ヘルス財団研究業績集. 2023. 46
小野宏晃, 史蕭逸, 上田泰己, 上田泰己. 睡眠と覚醒の科学第1回睡眠覚醒におけるCa²⁺依存的過分極経路機構. 睡眠医療. 2018. 12. 1. 91-96
大野怜一朗, 史蕭逸, 戸根大輔, 大出晃士, 洲崎悦生, 洲崎悦生, 上田泰己, 上田泰己. トリプルCRISPR法を用いた高効率な遺伝子ノックアウトマウス作出体制の実現. 日本実験動物技術者協会総会講演要旨集. 2016. 50th
史蕭逸, 洲崎悦生, 上田泰己. 脳の見える化-構造編細胞を見る脳の透明化と構造情報処理. Clin Neurosci. 2015. 33. 6. 639-642

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Patents (1)：

睡眠障害モデル非ヒト動物、睡眠障害評価用動物細胞、及びそれらを用いたスクリーニング方法

Lectures and oral presentations (13)：

Application of tissue-clearing method in sleep research
(The 3rd morphogenesis workshop 2020)
Identification of sleep genes by mathematical model and mouse genetics
(Synchronization phenomena on complex networks, from math to experiments -Special workshop for AIMR Advanced Target Projects- 2020)
Ca2+-dependent/-independent hyperpolarization pathway plays a role in sleep regulation -the first application of cubic in sleep research-
(Neuroscience 2019 2019)
Newly-identified sleep genes: The role of calcium dependent hyperpolarization pathway in sleep regulation
(World Sleep 2019 2019)
Understanding the role of Ca2+-dependent hyperpolarization pathway in sleep homeostasis
(NEURO2019 2019)

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Education (1)：

2013 - 2017 The University of Tokyo

Professional career (1)：

Ph.D. in Medicine (The University of Tokyo)

Work history (7)：

2022/03 - 現在 The University of Tokyo
2022/03 - 現在 University of Tsukuba International Institute for Integrative Sleep Medicine
2017/04 - 現在 RIKEN Center for Biosystems Dynamics Research
2020/04 - 2023/03 Keio University School of Medicine Department of Health Policy and Management
2020/10 - 2022/02 ERATO Ueda Biological Timing Project Group Leader

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Association Membership(s) (5)：

Society for Neuroscience (SfN) , European Sleep Research Society (ESRS) , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE PHARMACOLOGICAL SOCIETY , THE JAPAN NEUROSCIENCE SOCIETY

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