Research theme for competitive and other funds (27)：
2020 - 2023 KRAS mutations in lung cancer
2019 - 2023 The role of fusion genes in multistep progression of cancer
2019 - 2022 Specific immune responses against tumor antigens in long term survivors of cancer
2017 - 2022 The new method for detecting circulating tumor cells in lung cancerpatients
2016 - 2019 Two compartment model for lung cancer
2014 - 2018 Study on the novel molecular classification and individual therapy for pancreatic neuroendocrine carcinoma.
2013 - 2016 A novel model of signal transduction according to transcripts
2013 - 2015 Establishment of novel assay methods for translocation type gene alterations.
2011 - 2013 Elucidation of the molecular mechanisms and prognostic perspectives for ovarian cancer induced by iron overload due to endometriosis
2011 - 2011 肺癌のキナーゼ阻害剤治療の新しい展開・獲得耐性の克服と新規標的の探索
2009 - 2011 Analysis of lung adenocarcinoma according to molecular biological classification
2009 - 2011 MRM・MS and microRNA profiling analyses of blood samples and their clinical applications for development of molecular diagnostics
2008 - 2010 Molecular analysis of lung adenocarcinomas that do not have mutations in the EGFR pathway and development of therapeutic strategies against them
2007 - 2008 Analysis of EGFR and KRAS gene mutation in the early developmental phase of lung adenocarcinoma
2006 - 2007 Analyses of EGFR and related molecules for individulaization of geftinib treatment for lung cancer
2005 - 2006 Molecular classification of the lung cancer
2004 - 2005 Molecular and Clinical database and Molecular Staging for Lung Cancer
2003 - 2005 Integrated system of the tailor-made cancer treatment based on the expression profiling and bioinformatic analyses
2003 - 2004 肺腺癌のDNAメチル化による発現抑制と転移巣の解析
2000 - 2004 Multifaceted analysis of molecular pathogenesis of human lung cancers
2002 - 2003 Clinical significance of comprehensive expression analysis of cancer-related protein in non-small cell lung cancer using tissue microarray technology
2002 - 2002 腫瘍内多様性の解析と診断・治療への応用
2001 - 2002 肺がんの発生・進展への染色体不安定性の関与について
1997 - 1999 Genetic changes in the pathogenesis of lung cancer
1997 - 1998 Cyclin D1過剰発現リンパ腫の分子病理学的解析と臨床病態の解明
1997 - 1998 Functional Characterization of LIMK2 carrying LIM and PDZ Domains in the Developmental and Tumorigenic Process.
1996 - 1996 マントル細胞リンパ腫の生物学的および臨床病理学的解析
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Papers (756)：
Yuko Fujiwara, Ryou-U Takahashi, Motonobu Saito, Michinobu Umakoshi, Yoko Shimada, Kei Koyama, Yasushi Yatabe, Shun-Ichi Watanabe, Souichi Koyota, Yoshihiro Minamiya, et al. Oncofetal IGF2BP3-mediated control of microRNA structural diversity in the malignancy of early-stage lung adenocarcinoma. Proceedings of the National Academy of Sciences of the United States of America. 2024. 121. 36. e2407016121
Ken Asada, Syuzo Kaneko, Ken Takasawa, Kouya Shiraishi, Norio Shinkai, Yoko Shimada, Satoshi Takahashi, Hidenori Machino, Kazuma Kobayashi, Amina Bolatkan, et al. Multi-omics and clustering analyses reveal the mechanisms underlying unmet needs for patients with lung adenocarcinoma and identify potential therapeutic targets. Molecular cancer. 2024. 23. 1. 182-182
Hiroshi Ikeuchi, Yusuke Matsuno, Rika Kusumoto-Matsuo, Shinya Kojima, Toshihide Ueno, Masachika Ikegami, Rina Kitada, Hitomi Sumiyoshi-Okuma, Yuki Kojima, Kan Yonemori, et al. GLI1 confers resistance to PARP inhibitors by activating the DNA damage repair pathway. Oncogene. 2024
Mai Itoyama, Akihiro Ohara, Kazuki Yokoyama, Shun Yamamoto, Ken Kato, Yuichiro Tada, Ayumi Sugitani, Hirokazu Sugino, Yasushi Yatabe, Masahiko Kusumoto, et al. An autopsy case of pulmonary tumor thrombotic microangiopathy that developed during chemotherapy for salivary duct carcinoma of the parotid gland. Auris, nasus, larynx. 2024. 51. 5. 829-833
Shogo Nishino, Naoki Kojima, Hirokazu Sugino, Taisuke Mori, Yasushi Yatabe, Akihiko Yoshida. MUC5AC immunoreactivity in scattered tumor cells is useful for diagnosing CIC-rearranged sarcoma. Virchows Archiv : an international journal of pathology. 2024
2017 - Mary J. Matthews Pathology/Translational Research Award
2009 - Japan Lung Cancer Society Shinoi-Kawai Award
2003 - Japanese Society of Pathology Pathology Research Award
2003 - Japanese Cancer Association Incitement Award
2001 - Japanese Society of Pathology Young Investigator Award
Association Membership(s) (6)：
US-Canada Society of Pathology
, The International Association of Study of Lung Cancer
, THE JAPAN LUNG CANCER SOCIETY
, THE JAPANESE CANCER ASSOCIATION
, THE JAPANESE SOCIETY OF PATHOLOGY
, 日本臨床細胞学会
