Rchr
J-GLOBAL ID：201801013024712730   Update date: Apr. 30, 2025

Kurosaka Hiroshi

Kurosaka Hiroshi
Affiliation and department：
Osaka University Department of Orthodontics and Dentofacial Orthopedics

About Osaka University Department of Orthodontics and Dentofacial Orthopedics


Job title： Associate Professor
Research field  (2)： Oral medicine ,  Developmental dentistry
Research keywords  (8)： Developmental Biology ,  Rare Disease ,  Orthodontics ,  Craniofacial development ,  Cranial neural crest ,  Genetics ,  Cleft lip and/or Palate ,  Craniofacial defect
Research theme for competitive and other funds  (34)：
  • 2024 - 2028 New Strategies for Regeneration of the Mandibular Condylar Cartilage: Elucidating the Characteristics and Regulatory Mechanisms of Stem Cells and the Stem Cell Niche
  • 2024 - 2026 DNAバーコード標識化技術を深化させた全方位型シングルセルグライコミクスの実現
  • 2023 - 2026 遺伝子パネルを用いたプレシジョン・デンティストリーの構築と新規治療法の探索
  • 2023 - 2026 Development of a treatment method for maxillofacial dysplasia caused by parathyroid hormone (PTH) signaling disorder
  • 2023 - 2026 Development of a treatment method for maxillofacial dysplasia caused by parathyroid hormone (PTH) signaling disorder
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Papers (118)：
  • Tomoya Murotani, Hiroshi Kurosaka, Sayuri Yamamoto, Aikawa Tomonao, Susumu Tanaka, Takashi Yamashiro. Orthodontic-Surgical Approach for Treating Skeletal Class II Malocclusion with Severe Mandibular Hypoplasia in Williams Syndrome. 2025. In press
  • Rena Okawa, Tamami Kadota, Hiroshi Kurosaka, Hirofumi Nakayama, Marin Ochiai, Yuko Ogaya, Takuo Kubota, Takashi Yamashiro, Kazuhiko Nakano. Japanese nationwide dental survey of hypophosphatasia reveals novel oral manifestations. Scientific Reports. 2025. 15. 1
  • Yuka Yoshida, Toshihiro Inubushi, Mika Yokoyama, Priyanka Nag, Jun-ichi Sasaki, Ayaka Oka, Tomoya Murotani, Renshiro Kani, Yuki Shiraishi, Hiroshi Kurosaka, et al. <i>Slc26a2</i>-mediated sulfate metabolism is important in tooth development. Disease Models & Mechanisms. 2024. 17. 12
  • Hiroshi Kurosaka, Takashi Kimura, Jia-Yi Dong, Meishan Cui, Satoyo Ikehara, Kimiko Ueda, Hiroyasu Iso, Takashi Yamashiro. Higher risk of respiratory infections and otitis media in cleft lip and/or palate patients: the Japan Environment and Children’s Study. Environmental Health and Preventive Medicine. 2024. 29. 66
  • Shujie Liu, Lin Xu, Makoto Kashima, Rika Narumi, Yoshifumi Takahata, Eriko Nakamura, Hirotoshi Shibuya, Masaru Tamura, Yuki Shida, Toshihiro Inubushi, et al. Expression analysis of genes including Zfhx4 in mice and zebrafish reveals a temporospatial conserved molecular basis underlying craniofacial development. Developmental Dynamics. 2024. 254. 3. 257-271
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MISC (103)：
  • 伊藤 慎将, 森田 知里, 辻本 貴行, 黒坂 寛, 山城 隆. 原発性萠出不全症候群(PFE)の原因遺伝子解析. 日本矯正歯科学会大会プログラム・抄録集. 2024. 83回. 154-154
  • 石井 瞳, 黒坂 寛, 嘉ノ海 龍三, 山城 隆. Bone anchored maxillary protractionによる顎骨形態の変化について. 日本矯正歯科学会大会プログラム・抄録集. 2024. 83回. 155-155
  • 白石 優季, 犬伏 俊博, 長田 奈幹, 黒坂 寛, 山口 智美, 古庄 知己, 山城 隆. 筋拘縮型エーラスダンロス症候群患者の歯科的特徴と病態解明への取り組み. 日本矯正歯科学会大会プログラム・抄録集. 2024. 83回. 240-240
  • 黒坂 寛, 白石 優季, 伊藤 慎将, 森田 千里, 犬伏 俊博, 山城 隆. TFAP2A遺伝子の病的バリアントを同定したBranchio-Oculo-Facial Syndromeの顎顔面所見. 日本矯正歯科学会大会プログラム・抄録集. 2024. 83回. 276-276
  • 廣瀬 匠, 黒坂 寛, 村田 有香, 田中 晋, 山城 隆. 上顎両側犬歯の埋伏と下顎の著しい偏位に対して犬歯の牽引と外科的矯正治療を用いて良好な顔貌と咬合を獲得した症例. Clinical and Investigative Orthodontics (Japanese Edition). 2024. 83. 1. 8-15
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Patents (1)：
Books (1)：
  • Orthodontics for Dental Students
    Ishiyaku Publishers, Inc 2019
Lectures and oral presentations  (46)：
  • Diagnosis and orthodontic treatment planning for orthognathic surgery involving distraction osteogenesis
    (The 83rd Annual Meeting of the Japanese Orthodontic Society 2024)
  • Etiology of rare congenital craniofacial defects
    (2024)
  • 先天性顎顔面形成不全の発症メカニズム
    (広島大学 学際的研究研究推進部会 発生・発達・成長期医療グループセミナー 2024)
  • 鼻上顎複合体、咽頭の先天異常の原因となる分子メカニズム
    (第64回 日本先天異常学会学術集会 2024)
  • Orthodontic Management of Complications in Orthognathic Surgery
    (The 34th Annual Meeting of the Japanese Society for Jaw Deformities 2024)
ｍore...
Education (4)：
  • 2005 - 2007 Kyoto University Department of Biophysics, Graduate School of Science
  • 2003 - 2007 GRADUATE SCHOOL OF MEDICINE DENTISTRY AND PHARMACEUTICAL SCIENCES Department of Orthodontics
  • 2004 - 2005 RIKEN CDB Evolutionary Regeneration Biology Group
  • 1997 - 2003 Okayama University Department of Dentistry
Professional career (1)：
  • PhD (Okayama University)
Work history (7)：
  • 2022/04 - 現在 Graduate School of Dentistry, Osaka University Department of Orthodontics and Dentofacial Orthopedics Associate Professor
  • 2017/09 - 2022/03 Osaka University Dental Hospital Department of Orthodontics Lecturer
  • 2014/08 - 2017/08 Graduate School of Dentistry, Osaka University Department of Orthodontics and Dentofacial Orthopedics Assistant Professor
  • 2013/07 - 2014/07 University of Missouri-Kansas City Department of Orthodontics and Dentofacial Orthopedics Adjunct Assistant Professor
  • 2011/02 - 2014/07 Stowers Institute for Medical Research Craniofacial Development Lab (Trainor lab) Postdoctoral Research Associate
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Committee career (9)：
  • 2023/10 - 現在 日本先天異常学会 Congenital Anomalies, Associate Editor
  • 2023/04 - 現在 日本先天異常学会 幹事
  • 2020/01 - 現在 日本先天異常学会 将来計画検討委員会
  • 2020/01 - 現在 日本先天異常学会 評議員
  • 2018/07 - 現在 未診断疾患イニシアチブ(IRUD) 臨床専門分科会メンバー(歯科)
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Awards (21)：
  • 2024/07 - 大阪大学歯学部附属病院 病院長賞
  • 2023/05 - Poster award The function of retinoid signaling in establishing anteroposterior patterning in embryonic maxilla
  • 2022/07 - 大阪大学大学院歯学研究科 研究科長賞
  • 2021/11 - 第80回日本矯正歯科学会学術大会&第5回国際会議 優秀演題賞 Baraitser-Winter syndrome を引き起こすACTBの新規変異同定と機能解析
  • 2021/08 - The61st The Japanese Teratology Society Annual Meeting Excellent presentation award
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Association Membership(s) (9)：
日本先天異常学会 ,  JAPANESE STOMATOLOGICAL SOCIETY ,  THE JAPAN SOCIETY OF HUMAN GENETICS ,  The Japanese Society for Jaw Deformities ,  JAPANESE CLEFT PALATE ASSOCIATION ,  International Association of Dental Research ,  JAPANESE ASSOCIATION FOR ORAL BIOLOGY ,  JAPANESE ORTHODONTIC SOCIETY ,  Angle Midwest E.H. Angle Society (Active Member at Large)
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