Takada Hitomi

Affiliation and department：

Research field (2)： Gastroenterology , Developmental biology

Research keywords (5)：幹細胞分化制御 , 慢性炎症 , 消化器疾患 , organoid , pluripotent stem cells

Research theme for competitive and other funds (12)：

2022 - 2025 炎症が惹起する病的胃腺リモデリングの分子実態解明
2022 - 2024 難治性肺疾患の革新的治療技術の開発
2020 - 2023 胃臓器工学基盤技術の開発
2020 - 2022 Improvement of the lung tissue differentiation method and development of the gene therapy technology
2019 - 2022 Functional enhancement of MSCs based on analysis of expression profiles of secreted factors

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Papers (18)：

Hitomi Takada, Yohei Sasagawa, Mika Yoshimura, Kaori Tanaka, Yoshimi Iwayama, Tetsutaro Hayashi, Ayako Isomura-Matoba, Itoshi Nikaido, Akira Kurisaki. Single-cell transcriptomics uncovers EGFR signaling-mediated gastric progenitor cell differentiation in stomach homeostasis. Nature Communications. 2023
Takanobu Mashiko, Kunihisa Tsukada, Hitomi Takada, Szu-Hsien Wu, Koji Kanayama, Rintaro Asahi, Masanori Mori, Akira Kurisaki, Shinichi Oka, Kotaro Yoshimura. Genetic and cytometric analyses of subcutaneous adipose tissue in patients with hemophilia and HIV-associated lipodystrophy. AIDS Research and Therapy. 2022. 19. 1. 14-14
Koji Kanayama, Hitomi Takada, Natsumi Saito, Harunosuke Kato, Kahori Kinoshita, Takako Shirado, Takanobu Mashiko, Rintaro Asahi, Masanori Mori, Kensuke Tashiro, et al. Hair Regeneration Potential of Human Dermal Sheath Cells Cultured Under Physiological Oxygen. Tissue engineering. Part A. 2020. 26. 21-22. 1147-1157
Osamu Hashimoto, Masayuki Funaba, Kazunari Sekiyama, Satoru Doi, Daichi Shindo, Ryo Satoh, Hiroshi Itoi, Hiroaki Oiwa, Masahiro Morita, Chisato Suzuki, et al. Activin E Controls Energy Homeostasis in Both Brown and White Adipose Tissues as a Hepatokine. Cell reports. 2018. 25. 5. 1193-1203
Takanobu Mashiko, Hitomi Takada, Szu-Hsien Wu, Koji Kanayama, Jingwei Feng, Kensuke Tashiro, Rintaro Asahi, Ataru Sunaga, Kazuto Hoshi, Akira Kurisaki, et al. Therapeutic effects of a recombinant human collagen peptide bioscaffold with human adipose-derived stem cells on impaired wound healing after radiotherapy. Journal of tissue engineering and regenerative medicine. 2018. 12. 5. 1186-1194

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MISC (4)：

高田仁実, 笹川洋平, 芳村美佳, 田中かおり, 二階堂愛, 栗崎晃. 胃の恒常性維持を司る幹細胞分化制御機構の解析. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd
櫛笥博子, 高田仁実, 木田泰之. オミックスアプローチによる褐色脂肪の組織発生過程における代謝変換. 日本分子生物学会年会プログラム・要旨集(Web). 2014. 37th
高田仁実, 齋藤裕, 光山統泰, 木田泰之. DNAメチル化解析より明らかになった脂肪細胞分化過程における2つのステージ. 日本分子生物学会年会プログラム・要旨集(Web). 2014. 37th
Teruhiro Okuyama, Hitomi Takada, Masanori Taira. Regulation of the presumptive eye region-specific gene Pax6 by the co-activator XLCL2. ZOOLOGICAL SCIENCE. 2006. 23. 12. 1178-1178

Patents (1)：

がん幹細胞の増殖抑制剤

Books (2)：

My medicine with gastric organoids
2021
オルガノイドによる消化器研究胃オルガノイド作製と病態モデル
2019

Awards (2)：

2023 - 奈良先端科学技術大学院大学梅園賞
2018 - 池田理化池田理化再生医療研究奨励賞

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