Research theme for competitive and other funds (3)：
2021 - 2024 Molecular mechanisms of involvment of vanin-1 with kidney disease and its application to drug discovery
2000 - 2002 Search and development of antitumor sed compounds produced yb microorganisms from marine organisms
1998 - 1999 Development of antitumor lead compounds produced by microorganisms from marine organisms
Papers (39)：
Shizuyo Horiyama, Noboru Hayama, Hiroki Yoneyama, Yoshihide Usami, Jun Haginaka. Identification of novel metabolites of abiraterone in human serum and their metabolic pathways. Analytical Sciences. 2024. 40. 1. 67-74
Yoshihide Usami, Kimika Nakamura, Yoshino Mizobuchi, Koji Mizuki, Shinya Harusawa, Hiroki Yoneyama, Takeshi Yamada. Enantiomeric composition of natural pericosine A derived from Periconia byssoides and alpha-glycosidase inhibitory activity of (-)-enantiomer. CHIRALITY. 2022
Hiroki Yoneyama, Keiko Hosohata, Denan Jin, Iroha Yoshida, Miyui Toyoda, Ikuko Kitamura, Shinji Takai, Yoshihide Usami. Design, synthesis, and evaluation of new vanin-1 inhibitors based on RR6. Bioorganic and Medicinal Chemistry. 2022. 65
Yoshihide Usami, Yoshino Mizobuchi, Mai Ijuin, Takeshi Yamada, Mizuki Morita, Koji Mizuki, Hiroki Yoneyama, Shinya Harusawa. Synthesis of 6-Halo-Substituted Pericosine A and an Evaluation of Their Antitumor and Antiglycosidase Activities. Marine Drugs. 2022. 20. 7
Hiroki Yoneyama, Mano Adachi, Aoshi Morita, Maki Nakagawa, Miho Baba, Kanako Yamawaki, Noboru Hayama, Shinya Harusawa, Yoshihide Usami. Synthesis of 5,6-Dihydro-4 H -pyrrolo[1,2- b ]pyrazoles and Homologs from 5-Substituted 2-(Alkynyl)tetrazoles via Microwave-induced Intramolecular Nitrile Imine-Alkyne 1,3-Dipolar Cycloaddition. Synthesis (Germany). 2022. 55. 6. 945-958
