OHKURA Naoto

Affiliation and department：
Homepage URL (1)： http://researchers.adm.niigata-u.ac.jp/html/200001010_ja.html

Research field (1)： Conservative dentistry and endodontics

Research keywords (6)：アスコルビン酸 , Prostaglandin E2 , Transporter , Odontoblast , The conservative treatment of the pulp , Dental pulp regeneration

Research theme for competitive and other funds (11)：

2021 - 2024 歯髄の創傷治癒・再生過程におけるGli1陽性幹細胞の動態と分化誘導機構の解明
2021 - 2024 Comprehensive study on establishment of pulp regenerative therapy based on the scientific evidences
2019 - 2022 ヒト歯髄の創傷治癒過程におけるM2マクロファージとシュワン細胞の相互作用の解明
2019 - 2020 The clarification of the pulp generation mechanism to improve the odontoblast differentiation by the transporter of ascorbic acid.
2016 - 2020 A study on the mechanisms of induction and differentiation of stem cells during wound healing and regeneration of dentin-pulp complex

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Papers (49)：

Yoshio Yahata, Keisuke Handa, Naoto Ohkura, Motoki Okamoto, Jun Ohshima, Shusaku Itoh, Nobuyuki Kawashima, Toshinori Tanaka, Nobuya Sato, Yuichiro Noiri, et al. Autologous concentrated growth factor mediated accelerated bone healing in root-end microsurgery: A multicenter randomized clinical trial. Regenerative therapy. 2023. 24. 377-384
Rosa Baldeon-Gutierrez, Naoto Ohkura, Kunihiko Yoshiba, Nagako Yoshiba, Aiko Tohma, Ryosuke Takeuchi, Razi Saifullah Ibn Belal, Naoki Edanami, Shintaro Takahara, Susan Gomez-Kasimoto, et al. Wound-healing Processes After Pulpotomy in the Pulp Tissue of Type 1 Diabetes Mellitus Model Rats. Journal of Endodontics. 2023
Naoto Ohkura, Hwa Kyung Nam, Fei Liu, Nan Hatch. Cranial Neural Crest Specific Deletion of Alpl (TNAP) via P0-Cre Causes Abnormal Chondrocyte Maturation and Deficient Cranial Base Growth. International Journal of Molecular Sciences. 2023. 24. 20. 15401-15401
Shoji Takenaka, Hiroshi Moro, Utako Shimizu, Takeshi Koizumi, Kei Nagano, Naoki Edanami, Naoto Ohkura, Hisanori Domon, Yutaka Terao, Yuichiro Noiri. Preparing of Point-of-Care Reagents for Risk Assessment in the Elderly at Home by a Home-Visit Nurse and Verification of Their Analytical Accuracy. Diagnistics. 2023. ahead of online. 14. 2407-2407
Naoki Edanami, Shouji Takenaka, Razi Saifullah, Ibn Belal, Kunihiko Yoshiba, Shintaro Takahara, Nagako Yoshiba, Naoto Ohkura, Yuichiro Noiri. In Vivo assessment of the Apatite-Forming Ability of New-Generation Hydraulic Calcium Silicate Cements Using a Rat Subcutaneous Implantation Model. Journal of Functional Biomaterials. 2023. 14. 213. ahead of online

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MISC (59)：

高原信太郎, 大倉直人, 吉羽邦彦, 吉羽永子, 竹中彰治, 枝並直樹, 庭野和明, 野杁由一郎. The comparison analyses of wound-healing mechanism according to the root development stage using the regeneration model rats. 日本歯科保存学会学術大会プログラムおよび講演抄録集(Web). 2023. 158th. 31-31
竹中彰治, 枝並直樹, 齋藤瑠郁, 大倉直人, 野杁由一郎. Development of Point of Care Testing to facilitate risk assessment for the elderly at home-Performance evaluation of a newly developed semi-quantitative rapid test for CRP level determination-. 日本歯科保存学会学術大会プログラムおよび講演抄録集(Web). 2023. 158th. 148-148
高原信太郎, 大倉直人, 吉羽永子, 竹中彰治, 枝並直樹, 吉羽邦彦, 野杁由一郎. The localization of various mesenchymal stem cell marker-positive cells in early healing stage after regenerative endodontic procedure. 日本歯科保存学会学術大会プログラムおよび講演抄録集(Web). 2023. 159th. 47-47
廣瀬陽菜, 藤政清志朗, 金丸慎吾, 松本典祥, 高原信太郎, 大倉直人, 枝並直樹, 野杁由一郎, 松崎英津子, 松崎英津子. Sphingosine-1-phosphate (S1P) receptor 1-mediated odontoblastic differentiation and mineralization of mouse apical papilla-derived stem cells. 日本歯科保存学会学術大会プログラムおよび講演抄録集(Web). 2023. 159th. 46-46
大倉直人, 大倉直人, 吉羽永子, 高原信太郎, GUTIERREZ Rosa Edith Baldeon, GOMEZ-KASIMOTO Susan, 井田貴子, 枝並直樹, 竹中彰治, 吉羽邦彦, et al. Impact of the tissue nonspecific alkaline phosphatase during the root formation. 日本歯科保存学会学術大会プログラムおよび講演抄録集(Web). 2023. 159th. 92-92

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Lectures and oral presentations (1)：

夢の虫歯治療〜削らないむし歯治療の現状〜
(日本歯科保存学会市民公開フォーラム 2019)

Education (4)：

2011 - 2014 Niigata University Graduate School of Medical and Dental Sciences Oral Life Science
2004 - 2008 Niigata University Faculty of Dentistry School of Dentistry
2002 - 2004 東北大学大学院薬学部博士前期2年の課程薬物送達学分野
1998 - 2002 富山医科薬科大学薬学部薬科学科

Professional career (2)：

歯科(博士) (新潟大学大学院)
薬学(修士) (東北大学大学院)

Work history (4)：

2016/09 - 現在 Niigata University Preventive and Conservative Dentistry, Medical and Dental Hospital
2020/03 - 2022/03 University of Michigan, School of Dentistry Department of Orthodontics and Pediatric Dentistry Research fellow
2012/04 - 2016/08 Niigata University Preventive and Conservative Dentistry, Medical and Dental Hospital
2011/04 - 2012/03 新潟県長岡市私立立川綜合病院歯科口腔外科医員

Awards (2)：

2018 - 日本歯科保存学会日本歯科保存学会奨励賞
2011 - 日本歯科保存学会デンツプライ賞

Association Membership(s) (6)：

日本歯科審美学会 , 日本歯内療法学会 , 歯科基礎医学会 , 日本接着歯学会 , 日本歯科保存学会 , 新潟歯学会

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